Gene Information

Name : lysS (SSP2239)
Accession : YP_302329.1
Strain : Staphylococcus saprophyticus ATCC 15305
Genome accession: NC_007350
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 2312975 - 2314462 bp
Length : 1488 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCAGAAGAAATGAATGACCAAATGCAGGTCCGTCGCCAAAAATTACAAGAACTATATGATTTAGGAATAGATCCATT
TGGTCAAAAATTTGATCGTACTTCAATGGCAACCCCATTACATGAAGACTGGGATCAATTTAGCAAAGAAGAATTACATG
AAAAAGAAGAAGAAAGTCATGTAAGTATTGCTGGACGTTTAATGACGAAACGCGGAAAAGGTAAAGCGGGCTTTGCACAC
GTTCAAGATTTAAGTGGTCAAATACAGATTTATGTAAGAAAAGACCAAGTAGGTGAAGATCAATTTGCTATTTGGAATTC
TGCAGATCTTGGAGATATAGTAGGCGTGGAAGGCGTAATGTTTAAAACTAACACTGGTGAACTATCAGTTAAAGCACAGT
CATTCACTTTATTAACAAAAGCCTTACGTCCACTCCCAGATAAGTTCCATGGCTTACAAGATATAGAACAACGTTATCGT
CAGCGTTATTTAGACCTAATTACTAACCAAGATAGTACACAAACATTCATTAAACGTAGTAAAATATTGCAAGAGATGCG
TAACTATTTAAATCAACAAGGATTTTTAGAAGTAGAAACACCTATGATGCATCAAATCGCAGGTGGAGCAGCTGCACGTC
CTTTCGTTACACATCATAATGCGTTAGACGCTACTTTATATATGAGAATTGCGATTGAATTACATTTGAAACGTTTAATT
GTTGGTGGATTAGAAAAAGTTTATGAAATAGGTCGTGTATTTAGAAATGAAGGTGTGTCTACAAGACATAATCCGGAATT
TACTATGATTGAATTATATGAAGCTTACGCTGATTATCATGATATTATGGATATTACAGAAAATATGATTAGACATATAT
CTGAAAAAGTATTAGGTACTGCGAAAGTAACGTATGGAGAAGAAACAATAGATTTAGAATCTAAATGGAAACGAATCCAT
ATGGCCGATGCCGTTAAAGAAGAAACAGGTGTCGACTTCTTCAACATTCAAAGTGACGAAGATGCGAAAATAGCTGCTAA
AGAACACGGCATAGAAATTACAGATAATATGAAATATGGTCATATATTAAATGAGTTCTTTGAACAAAAAGTTGAAGAAA
CACTCATTCAACCAACATTTGTATATGGTCACCCAATTGAAATCTCTCCATTAGCTAAGAAAAATGCGGAAGATCCAAGA
TTTACAGATCGTTTTGAGTTGTTTATTGTTGGAAGAGAACACGGTAATGCATTTACTGAATTAAATGATCCAATCGATCA
AAGAGCAAGATTTGAAGCGCAATTAGTAGAAAAAGAACAAGGCAACGATGAAGCACATGAAATGGATGAAGACTTTATCG
AGGCGTTAGAATATGGTATGCCTCCTACAGGTGGATTAGGGATCGGAATTGACAGATTGGTTATGTTACTTACAGATTCT
GCCTCTATTAGAGACGTATTACTGTTCCCTTATATGAGACAAAAATAA

Protein sequence :
MSEEMNDQMQVRRQKLQELYDLGIDPFGQKFDRTSMATPLHEDWDQFSKEELHEKEEESHVSIAGRLMTKRGKGKAGFAH
VQDLSGQIQIYVRKDQVGEDQFAIWNSADLGDIVGVEGVMFKTNTGELSVKAQSFTLLTKALRPLPDKFHGLQDIEQRYR
QRYLDLITNQDSTQTFIKRSKILQEMRNYLNQQGFLEVETPMMHQIAGGAAARPFVTHHNALDATLYMRIAIELHLKRLI
VGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYHDIMDITENMIRHISEKVLGTAKVTYGEETIDLESKWKRIH
MADAVKEETGVDFFNIQSDEDAKIAAKEHGIEITDNMKYGHILNEFFEQKVEETLIQPTFVYGHPIEISPLAKKNAEDPR
FTDRFELFIVGREHGNAFTELNDPIDQRARFEAQLVEKEQGNDEAHEMDEDFIEALEYGMPPTGGLGIGIDRLVMLLTDS
ASIRDVLLFPYMRQK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-118 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_302329.1 lysyl-tRNA synthetase VFG1668 Protein 9e-119 50