Gene Information

Name : leuS (SSP1006)
Accession : YP_301096.1
Strain : Staphylococcus saprophyticus ATCC 15305
Genome accession: NC_007350
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1036870 - 1039284 bp
Length : 2415 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGAATTACAGTCATAATGAAATTGAAAAGAAATGGCAGGACTATTGGGAAGCAAATAAAACTTTTAAAACGAGCGACAA
TTTAGGGCAAAAGAAATTTTATGCTTTAGATATGTTCCCTTATCCATCAGGAGCAGGCCTGCATGTTGGTCACCCAGAAG
GGTATACTGCTACAGATATCATCTCTCGTTATAAACGTATGTTAGGTTATAACGTATTACACCCAATGGGTTGGGATGCA
TTTGGCTTACCAGCTGAACAATATGCATTAGATACAGGTAATGATCCACGAGAGTTCACTAAAGAAAATATTCAGACCTT
TAAGCGTCAGATAAAAGAACTTGGTTTCAGTTATGACTGGGATAGAGAAGTGAATACGACAGATCCTGAATACTACAAAT
GGACACAATGGATTTTCATACAATTATATAATAAAGGTTTAGCTTATGTAGATGAAGTGGCTGTGAATTGGTGTCCAGCA
TTAGGTACGGTATTATCGAATGAAGAAGTTATTGATGGCGTATCAGAACGTGGCGGCCATCCTGTATATAGACGTCCAAT
GAAGCAATGGGTTCTTAAAATTACCGAATATGCAGACAGATTGTTAGAAGATTTAGATGAATTAGACTGGCCAGAGTCAT
TGAAAGATATGCAACGTAACTGGATTGGCCGTTCTGAAGGTGCATCAGTGGCATTTGATGTGAAAGATTATAATGAGCAA
ATTGAAGTATTTACTACTAGACCTGATACAATATACGGTGCGTCATTTTTAGTGCTTAGCCCAGAACACGAGCTTGTAGA
TTTGATTACTACGGAAGATAATAAAGATGATGTAGAAGCTTATCAAAAAGAAGCGGCTAAGAAATCTGATTTAGAACGTA
CTGGCTTATCAAAAGAAAAGTCTGGTGTATTCACTGGTGCATATGCTGTTAATCCATTATCAGGGCAACAAGTACCAATA
TGGATTGCAGATTACGTACTATCCACTTACGGTACTGGTGCGGTCATGGCTGTACCTAGTGGTGATCAGCGTGATTATGA
ATTCGCTAAAACATTTGACTTACCAATTATAGAAGTCATCGAAGGCGGAGATATGAGCAAGGAAGCCTACACTGGCGACG
GACCGCATATTAATTCTGGTGAACTAAACGGATTATACAATGAAGCAGCTATAGAAAAAGCGATTGAATTGTTAGAAAAT
AAAAATGCCGGTACGCGTAAAGTAAACTACAAACTTAGAGATTGGTTGTTCAGTAGACAAAGATATTGGGGCGAACCTAT
TCCAGTTATTCACTGGGAAGATGGCTCAATGACGACAGTACCTGAAGATGAACTACCATTACTTTTACCAGAAACTGATG
AAATAAAACCGTCAGGGACAGGTGAATCACCGTTAGCGAATATTGATGAATTTGTAAACGTTGTCGATGAAGCCACAGGT
ATGAAAGGCCGCCGTGAAACAAATACGATGCCACAATGGGCAGGTAGCTGTTGGTATTATCTAAGATATATTGATCCAGA
CAATGAGCAAATGTTAGCAGATCCTGAAAAATTAAAACATTGGTTGCCTGTAGATTTGTATATTGGTGGCGTAGAACATG
CTGTATTACATTTATTGTATGCACGATTTTGGCACAAAGTATTATTTGATTTAGGTGTGGTACCAACAAAAGAACCATTC
CAAAAGTTATTCAACCAAGGTATGATTTTGGGTGAAGGTAACGAAAAAATGAGTAAATCTAAAGGTAATGTAATTAATCC
AGATGATATTGTAAAATCTCATGGTGCGGATACGTTACGTTTATATGAGATGTTTATGGGACCGCTTGATGCCGCTATCG
CTTGGAGCGAAAATGGTTTAGATGGTTCGAGACGTTTCTTAGATAGGATTTGGCGTTTATTAATTACAGAAGATGGTTCA
ATTTCTAATAAAGTGGTAAACAATCATAGTAAGGCTTTAGATAAGAGTTATCACCAAACAGTGAAAAAAGTTACAGAAGA
TTACAATTCGCTTAACTTTAACACAGCGATTAGTCAACTTATGGTATTTATTAATGATTGTTATAAAGCGGAAGAAATTT
ATAAACCATATATCGAAGGCTTTATTAAAATGCTGGCGCCGATTGCACCTCATATATCTGAAGAATTGTGGTCACGTTTA
GGCCATGATGAAACAATCACTTATCAACCATGGCCATCCTACGATGAAGCGTTACTTGTTGATGACGAAATTGAGATTGT
CGTACAAGTAAATGGTAAAGTGCGTGCTAAAATTAATGTATCGAAAGATATTGCGAAAGAAGAAATGGAGCAAATCGCAC
TAGATAATGAACATGTTAAATCTGAAATAGAAGGTAAAGATATTAAAAAAGTTATTGCAGTTCCTAAAAAACTTGTTAAT
ATCGTCGCTAAATAA

Protein sequence :
MNYSHNEIEKKWQDYWEANKTFKTSDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIISRYKRMLGYNVLHPMGWDA
FGLPAEQYALDTGNDPREFTKENIQTFKRQIKELGFSYDWDREVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPA
LGTVLSNEEVIDGVSERGGHPVYRRPMKQWVLKITEYADRLLEDLDELDWPESLKDMQRNWIGRSEGASVAFDVKDYNEQ
IEVFTTRPDTIYGASFLVLSPEHELVDLITTEDNKDDVEAYQKEAAKKSDLERTGLSKEKSGVFTGAYAVNPLSGQQVPI
WIADYVLSTYGTGAVMAVPSGDQRDYEFAKTFDLPIIEVIEGGDMSKEAYTGDGPHINSGELNGLYNEAAIEKAIELLEN
KNAGTRKVNYKLRDWLFSRQRYWGEPIPVIHWEDGSMTTVPEDELPLLLPETDEIKPSGTGESPLANIDEFVNVVDEATG
MKGRRETNTMPQWAGSCWYYLRYIDPDNEQMLADPEKLKHWLPVDLYIGGVEHAVLHLLYARFWHKVLFDLGVVPTKEPF
QKLFNQGMILGEGNEKMSKSKGNVINPDDIVKSHGADTLRLYEMFMGPLDAAIAWSENGLDGSRRFLDRIWRLLITEDGS
ISNKVVNNHSKALDKSYHQTVKKVTEDYNSLNFNTAISQLMVFINDCYKAEEIYKPYIEGFIKMLAPIAPHISEELWSRL
GHDETITYQPWPSYDEALLVDDEIEIVVQVNGKVRAKINVSKDIAKEEMEQIALDNEHVKSEIEGKDIKKVIAVPKKLVN
IVAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 64