Gene Information

Name : leuS (PMN2A_0321)
Accession : YP_291516.1
Strain : Prochlorococcus marinus NATL2A
Genome accession: NC_007335
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 860178 - 862766 bp
Length : 2589 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
TTGAATAATACTACTTCAGATATTAATGACCAGCGATACGAGCCTCGGGAAGTAGAAGCTTATTGGCAAAAAGAATGGGC
TAGTGATGACCTTTATAGGACAAATACTGAAGTAAATAAAGAAAATACTTTCTATGCCTTGTCCATGTTTCCATACCCAT
CAGGTTCTTTACATATGGGTCACGTCAGGAATTATGTAATTACAGACGTGCTCGCTAGATATAAAAGGATGAAAGGTTTT
AACGTCCTACATCCAATGGGTTGGGATTCCTTCGGTTTACCTGCTGAAAATGCAGCAATAGAGAGAGAAATAAGTCCATC
GACATGGACAGATAAAAATATTTCACAAATGAAAGATCAATTAGATCGTCTAGGACTATCAATAGATTGGTCTAAAGAAG
TTACTACTTGCAAAGAAGAATATTATAAATGGACTCAATATATATTTAATCAATTACATAAAAATAATCTTGCCTATCAA
AAAAAAGCAACAGTTAATTGGGATCCAATTGATCAAACTGTTCTTGCTAATGAGCAAGTAGACGCTGAAGGTAAATCATG
GAGATCTGGAGCTAAAGTTGAGAAAAAAGAATTAAATCAGTGGTTTTTACGAATTACTAGTTTCGCCGAAGATCTTAATA
AGGATTTAATTAAGCTTAATGACTGGCCAGATAGAGTAAGAGTTATGCAAAAAAATTGGATTGGTAAATCCATCGGAGCA
GAAATAACATTTGAAATCAAAAATAGCGACCAAAAAATAACAGCATTCACAACAAGAATAGATACCGTTTATGGAGTGAG
TTATCTGGTATTAGCATCGAATCATCCATTAATTGATCAATTAATAAGTTCTAATGATATAGATAAATTAAATGACTTTA
GACAAACTCAAGAAAAGTTAAGTGATCTTGAACGTAATTCAGATACTAGACAAAAACTTGGAATGTACTTAGGAGTAGAT
GCAATTAATCCAGCAAATAATAAAGAGATACCGATTTGGATAGGAGACTATGTGATTATGGAATATGGAACTGGTGCTGT
GATGGGTGTTCCAGCTCACGATAGTAGAGATTATCAGTTTGCAAAATCATATGATTTACCAATTCAATATGTAATAAAAC
CCAATATTGATGAAGATGAAAGTTATTTAAATGCTGAATTTGTTGATAAAGGAATCATGATCAATTCAGATAAATTTAAT
GGTATTGAATCTGATATTGCAAAAACACAAATACTTGAATTTGGTTCAAATTCAAATTGGGCAAAACCAAAGATCACATA
CAAATTAAGAGATTGGCTTATATCTAGACAACGATATTGGGGCTGCCCAATTCCGATTATTAATTGTAAGAAGTGTGGCC
AAGTAAGAGTCCCTGACAATGATCTTCCAGTTGTACTACCAATTGATATTAAATTAACTGGTAAAGGTAAGAGTCCTTTA
ACAACCAAAACCGAATGGATAAATACTTGTTGCCCAAAATGTGGAACTGAAGCAAAAAGAGAAACTGATACAATGGACAC
TTTTATGTGTTCATCTTGGTACTTTTTAAGATATATAAATCCTGATAATTGTGAAAAGCCTTTTCTGAAAAGCGAAATAG
ACAAATGGCTTCCAGTTAAGCAGTATGTTGGTGGTATCGAGCACGCTATTTTACATTTACTATATTCTAGATTTTTAACC
AAGGCTCTCAAGAAATGTGGATTAATAAATATCGATGAACCTTTTAAGAAACTGCTAACTCAAGGGATGGTTCAAGCCGT
TACTTTTAAAAATCCCAATACAAATAAATATTTTTCAAAGGATCAAATTAAAGATATTGATAATCCTAAAGATCCACTTA
CAGGAGAGAATATTGAAATCATCTATGAAAAGATGTCGAAGTCAAAATACAATGGTGTAGATCCATCTGTAGTGATAGAT
AAATATGGAGCTGACACAGCAAGAATGTTTATTCTTTTTAAAGCTCCACCAGAGAAAGATTTAGAGTGGGATGACTCCGA
TGTCGAAGGGCAATACCGATTTATACAGAGACTCTGGAAATTTGTTATTAATACTTTTAAACTAACAAATAATAATTCAA
GATCTAATATAGAAAAAGAAAAGTCTAAAGACGAAGAGGCTTTACGCCTAATTAATATTGCTATTAAGGAAATTACTGAT
GATTTGGATAATCTTCAATTTAATACAGCAATATCTGAACTTATGAAGGTTGTAAATGGCCTAAGTTTAATAGTTAATTA
CTGTAGTAATGAAACTCTAAATAAAGTTATTTCAATATTAGTTAAAATAACTTCTCCATTTTCTCCTCATATTGCAGAGG
AGCTTTGGAAGACAATCGGAAATACTCAAAGTATTCATCTTCAGTCATGGCCAGAATTTGATGCAGGTGCAATTGAACAA
GATACTTTTAAACTTATGATTCAAATAAATGGAAAAGTTAGAGGATCAATTAATGCTAGTAAAAATCTATCTAAAGAAAA
TTTAGAGGACTTAGCTATTAAAACTGAGGCTGCTATAAAATGGATGGATGGAAAGGAACCAAAACGAATAATTGTTGTCC
CGAATAAATTAGTAAATATAGTTATTTAG

Protein sequence :
MNNTTSDINDQRYEPREVEAYWQKEWASDDLYRTNTEVNKENTFYALSMFPYPSGSLHMGHVRNYVITDVLARYKRMKGF
NVLHPMGWDSFGLPAENAAIEREISPSTWTDKNISQMKDQLDRLGLSIDWSKEVTTCKEEYYKWTQYIFNQLHKNNLAYQ
KKATVNWDPIDQTVLANEQVDAEGKSWRSGAKVEKKELNQWFLRITSFAEDLNKDLIKLNDWPDRVRVMQKNWIGKSIGA
EITFEIKNSDQKITAFTTRIDTVYGVSYLVLASNHPLIDQLISSNDIDKLNDFRQTQEKLSDLERNSDTRQKLGMYLGVD
AINPANNKEIPIWIGDYVIMEYGTGAVMGVPAHDSRDYQFAKSYDLPIQYVIKPNIDEDESYLNAEFVDKGIMINSDKFN
GIESDIAKTQILEFGSNSNWAKPKITYKLRDWLISRQRYWGCPIPIINCKKCGQVRVPDNDLPVVLPIDIKLTGKGKSPL
TTKTEWINTCCPKCGTEAKRETDTMDTFMCSSWYFLRYINPDNCEKPFLKSEIDKWLPVKQYVGGIEHAILHLLYSRFLT
KALKKCGLINIDEPFKKLLTQGMVQAVTFKNPNTNKYFSKDQIKDIDNPKDPLTGENIEIIYEKMSKSKYNGVDPSVVID
KYGADTARMFILFKAPPEKDLEWDDSDVEGQYRFIQRLWKFVINTFKLTNNNSRSNIEKEKSKDEEALRLINIAIKEITD
DLDNLQFNTAISELMKVVNGLSLIVNYCSNETLNKVISILVKITSPFSPHIAEELWKTIGNTQSIHLQSWPEFDAGAIEQ
DTFKLMIQINGKVRGSINASKNLSKENLEDLAIKTEAAIKWMDGKEPKRIIVVPNKLVNIVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 2e-165 41