Gene Information

Name : lysS (PMN2A_1195)
Accession : YP_292388.1
Strain : Prochlorococcus marinus NATL2A
Genome accession: NC_007335
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1683417 - 1684958 bp
Length : 1542 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
TTGCCGTATGTACCCATTGCCTTGTCTGAATTAAGAGATACGCGCCTCGAGAAGGCAAAAGCACTAAAAACCCTTGGGAA
AGGTCCCTATGGTTTGAATTTTCGACCTACTGACTCTGCCGCTGTTTTGCAGGGAAAATATAAAGACTTACCAAATGGCG
AAGAAAAAAAAGACGAAGTATCTATCGCAGGGCGAGTAACTTCTAGAAGAGTGATGGGAAAACTTGCTTTTTTTACTCTT
TCCGATGAAACAGGCATAATTCAACTCTTTTTGGAAAAGGCGACCTTAAATCGGAATGAAGATAGTGAGAATCCAAAGAA
TAATTTTGAGAACATTACCTCTTTGGTTGACTCTGGTGATTGGATAGGAGTCAGTGGAATATTAAGGAGAACTGATAGAG
GTGAACTTTCTATAAAGGTTTTCGAATGGTCAATGCTATCAAAATCTTTACAACCCCTACCAGATAAATGGCATGGACTT
GCCGATGTAGAAAAGCGCTATAGACAAAGATATTTAGATTTAATTGTAAATCCACAGTCAAGAAAAACTTTTCGAACTAG
GGCTTTATTAGTTAGTTCAATTCGACGTTGGTTAGATGAAAAAGACTTTCTTGAAATCGAGACTCCAGTTTTACAATCAG
AAGCTGGAGGAGCGGATGCAAGGCCTTTCATAACTCATCACAACACGCTCGATTTACCTTTGTATCTGAGGATTGCAACA
GAATTGCATCTTAAAAGACTTGTGGTGGGTGGATTTCAAAGGGTCTATGAACTTGGAAGAATTTTTAGAAATGAAGGAAT
TAGCACAAGGCATAATCCTGAATTTACTTCTGTTGAAATTTATGAGGCCTTTGCAGATTATTTCGACATGATGGATTTAA
CAGAAAAATTACTTTCTTCAGTTTGCGAAAAGATTTGTGGATCGACCAAAATTAATTATCAAGAGCAAGAAATAGATTTG
CAACCTCCTTGGAGAAGGGCCACGATGCATGATTTAGTTAAGGAATTTACTGGAATTGATTTTGAATTATTTGGAGACAA
TGTTGATGATGCTAAGGCTGAAATGAGTCGAGAGGGGCTTCAAGTGCCTGATAAGGCTGATACTGTTGGAAGCCTATTAA
ATGAAGCTTTTGAGCAAGCAGTAGAGCCTGAACTGATTCAGCCTACATTTGTCATGGATTATCCAATTGAGATTTCTCCA
TTGGCTAGAAAACATAGAACTAAAAAAGGTTTAGTGGAAAGATTTGAACTTTTTATTGTTGGTAGAGAAACTGCCAATGC
TTTTAGCGAATTAATTGACCCTATTGATCAAAGAGAACGTTTACTTTTACAGCAAGCGAAAAAAGAAGCAGGTGATCTTG
AGGCTCAAAGCCTGGATGAGGATTTTATCAATGCTCTTGAGGTCGGAATGCCTCCCACAGGAGGTCTTGGAATAGGAATA
GATAGGTTTGTAATGTTGTTAACAGATAGTCCTTCCATAAGAGATGTAATAGCTTTTCCACTTTTACGACCAGAAGCAAA
TTTAAAACAAACTGCAAAGTGA

Protein sequence :
MPYVPIALSELRDTRLEKAKALKTLGKGPYGLNFRPTDSAAVLQGKYKDLPNGEEKKDEVSIAGRVTSRRVMGKLAFFTL
SDETGIIQLFLEKATLNRNEDSENPKNNFENITSLVDSGDWIGVSGILRRTDRGELSIKVFEWSMLSKSLQPLPDKWHGL
ADVEKRYRQRYLDLIVNPQSRKTFRTRALLVSSIRRWLDEKDFLEIETPVLQSEAGGADARPFITHHNTLDLPLYLRIAT
ELHLKRLVVGGFQRVYELGRIFRNEGISTRHNPEFTSVEIYEAFADYFDMMDLTEKLLSSVCEKICGSTKINYQEQEIDL
QPPWRRATMHDLVKEFTGIDFELFGDNVDDAKAEMSREGLQVPDKADTVGSLLNEAFEQAVEPELIQPTFVMDYPIEISP
LARKHRTKKGLVERFELFIVGRETANAFSELIDPIDQRERLLLQQAKKEAGDLEAQSLDEDFINALEVGMPPTGGLGIGI
DRFVMLLTDSPSIRDVIAFPLLRPEANLKQTAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-103 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_292388.1 lysyl-tRNA synthetase VFG1668 Protein 1e-103 47