Gene Information

Name : lysS (Tfu_2881)
Accession : YP_290937.1
Strain : Thermobifida fusca YX
Genome accession: NC_007333
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 3394865 - 3396355 bp
Length : 1491 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
GTGAGTGAAGTACTGGATGATCTGCCGGAACAGATGCGGGTTCGCCGCGAGAAGCTGGACCGACTGCGTCGGGAGGGTGT
CGACCCCTACCCGGTGACCTTCCCGCGCACGACGACGATCGCAGAGGTCCGGGCGAAACACGGCGATCTCGCTCCGGACG
TCTACACCGGGGAACGCGTGGCCCTGACCGGGCGGGTCATGCTGTATCGGACCGGCGGCAAACTCTGCTTCGCCACGATC
CGGGACGCGTCCGGGGACATCCAGGTCATGCTCTCCCTGGACAGGGTGGGCGCCGAGCGTTTGGCGGCGTGGAAGAGCGA
CGTCGACCTGGGCGACCACATCGGTGTCGAAGGGGAAGTGATCACTTCTCGGCGAGGCGAGTTGTCGATCCTCGCGGACA
CCTGGACGCTGACCTCCAAGTGCCTGCGCCCGCTGCCGGACAAGCACAAGGGGCTGACCGACCCTGAGGCACGGGTGCGC
CAGCGCTACGTGGACCTTATCGTCAACCCCGAGTCGCGGGAGATGGTGATGCGCCGCGCCCGCACGGTGCGTGCGCTGCG
CGACGGGCTGCACAACCGCGGCTACATCGAGGTTGAGACGCCGATGCTGCAGCAGGTGCACGGCGGGGCGACGGCACGCC
CCTTCGTCACCCACATCAACGCCTACGACCTCGACCTCTACCTGCGCATCGCCCCCGAACTGTACTTGAAGCGGATGGTG
GTCGGCGGGGTTGAGAAGGTCTTCGAAATCAACCGGAACTTCCGGAACGAGGGCGCGGACTCCACGCACAACCCCGAGTT
CACGATGCTGGAGTTCTACCAGGCCTACGCGGACTACAACGTGATGGCCGACATCACCCGCGAACTCATCCAGGAAGCCG
CCGTCGCAGTGTTCGGCAGCACGGTGGTCCAGCGGGGCGACACAGAGGTCGACTTGGGCGGCGAGTGGCCGCAGATCACC
TTGTACGGCGCGGTCTCTGAAGCGCTGGGCGAAGAAGTCACTCCGCGGACCCCGGTGGAGACGCTGCGGAAGCTGGCGGA
TGCGCGCGGTGTCGAATGGAACCCGGAGTGGGGTCCGGGCAAGCTCGTCGAGCACCTTTTCGAGGAGTTGGTCCAAGACA
GCCTGGTGCAGCCGACTTTTGTCCGGGACTACCCGCTTGAAACCAGCCCGCTGACCCGCCAGCACCGTGAAGACCCGCTG
CTCACCGAGAAGTGGGATCTCATCGGATTCGGTATGGAGTTGGGCACCGGATATTCCGAGTTGATTGATCCGGTGGAGCA
GCGCCGCCGCTTGACTGAGCAGTCTCTGCTGGCTGCCGGGGGCGATCCCGAGGCAATGCAGTTGGACGAGGATTTTCTGC
GCGCCTTGGAGTACGCCATGCCGCCTACCGGCGGTGTCGGTGTGGGCGTCGACCGGCTGTTGATGGCCTTTACCGGAAAG
AACATTCGCGAGACGATCCTGTTCCCATTGGTCCGACAGGAACAGAGATAA

Protein sequence :
MSEVLDDLPEQMRVRREKLDRLRREGVDPYPVTFPRTTTIAEVRAKHGDLAPDVYTGERVALTGRVMLYRTGGKLCFATI
RDASGDIQVMLSLDRVGAERLAAWKSDVDLGDHIGVEGEVITSRRGELSILADTWTLTSKCLRPLPDKHKGLTDPEARVR
QRYVDLIVNPESREMVMRRARTVRALRDGLHNRGYIEVETPMLQQVHGGATARPFVTHINAYDLDLYLRIAPELYLKRMV
VGGVEKVFEINRNFRNEGADSTHNPEFTMLEFYQAYADYNVMADITRELIQEAAVAVFGSTVVQRGDTEVDLGGEWPQIT
LYGAVSEALGEEVTPRTPVETLRKLADARGVEWNPEWGPGKLVEHLFEELVQDSLVQPTFVRDYPLETSPLTRQHREDPL
LTEKWDLIGFGMELGTGYSELIDPVEQRRRLTEQSLLAAGGDPEAMQLDEDFLRALEYAMPPTGGVGVGVDRLLMAFTGK
NIRETILFPLVRQEQR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 1e-122 54
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 6e-87 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_290937.1 lysyl-tRNA synthetase VFG1668 Protein 3e-87 44