Gene Information

Name : leuS (Tfu_2156)
Accession : YP_290212.1
Strain : Thermobifida fusca YX
Genome accession: NC_007333
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 2526315 - 2528807 bp
Length : 2493 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGACAGCGGTTAGCGGCGATCAGACGACGAGTGGCTCCTACGACGTCCGGGCACTCCAGGAGAAGTGGCAGGCCCGGTG
GGCAAAGGAGAACCCCTTCACGGCTAGCGAAGACCCGGCCGACCCCCGTCCGCGACGCTATGTGCTCGACATGTTCCCCT
ACCCCTCAGGTGACCTCCACATGGGGCACGCTGAGGCGTTCGCGATCGGCGACGTCATCGCGCGCTACCACTTCGCGCGC
GGGGAGAACGTGCTGCACCCGATCGGCTGGGACTCTTTCGGCCTGCCCGCGGAGAACGCCGCCATCAAACACAACTTCCA
CCCGGCCGAGTGGACCTACACCAACATTGAGACCCAGGCCGAGTCGTTCCGGCGCTACGCCATCTCTTTGGACTGGTCCC
GTCGTCTGCACACCAGCGACCCCGAGTACTACCGCTGGAACCAGTGGTTCTTCCTCCGGTTCTTCGAACGCGGTCTGGCC
TACCGCAAGGACGGCCTGGTCAACTGGTGCCCCAAGGATCAGACCGTGCTCGCCAATGAGCAGGTCATCCAGGGCAAGTG
CGAGCGCTGCGGCACCGAGGTCGAGCGGCGGGCGCTCAACCAGTGGTACTTCAAGATCACGGACTACGCCCAGCGGCTGC
TGGACGACATGGAGCAGCTCGAGGGCAAGTGGCCCGAGCGCGTGCTGACCATGCAGCGCAACTGGATCGGCCGTTCGGAA
GGCGCTGACGTCCAGTTCACTATCGAAGGCCGCGAGGAACCGGTCACCGTCTTCACTACGCGACCCGACACCCTGTACGG
GGCGACGTTCTTCGTGGTCGCCCCCGACTCGCCGCTGGCCGACGAACTGTGCGCGCCTGAACAGCGGGAAGCGTTCGAGG
CCTACCGCACCCAGGTCAGCAAGCTGAGTGACATCGAACGCCAGTCGACCGAGCGGGAGAAGACCGGCGTCTTCCTGGGC
CGCTACGCGATCAACCCGGTCAACGGGGAGCGCATCCCGGTCTGGGCGGCCGACTACGTACTGGCCGACTACGGCCACGG
CGCGATCATGGCGGTGCCCGCACACGACCAGCGCGACCTGGACTTCGCCCGCAAGTTCAACCTGCCGGTCCGTGTTGTCG
TGGACACGGGCGAGCCCGACCCCGCTGAGACGGGGATCGCCACCCCCGGGGAGGGCACGCTCATCAACTCCGGTCCGCTG
AACGGCCTCAGCAAGAGCGAAGCGATCCCCCGCATCATCGAGATCCTCACCGAACGCGGCACCGGCAAGGCCGCCGTCAA
CTACCGGCTGCGCGACTGGCTGGTGTCCCGCCAGCGGTTCTGGGGCACTCCCATTCCGATCATCCACTGCCCGGAGTGCG
GCGAAGTTCCGGTCCCCGACGAAGAACTGCCGGTGCGCCTGCCCGACCTGCGCGGGGCTGCCCTAGCCCCCAAGGGGGTC
TCCCCGCTGGCCGCCGCCACCGACTGGGTCAACGTGTCCTGCCCCCGCTGCGGCGGGCCCGCCAAACGGGACACGGACAC
GATGGACACCTTCGTCGACTCCTCCTGGTACTTCTTGCGCTACTGCTCGCCCAACCTGGACACCGCGCCGTTCGACCAGG
AGAAAGTCGCCAAGTGGGGACCGATCGACCAGTACGTCGGCGGTGTCGAGCACGCGATCCTGCACCTGCTCTACAGCAGG
TTCTTCACCAAGGTCCTCTACGACATGGGCATGGTGCCGTTCACCGAGCCCTTCGTCCGGCTGCTCAACCAGGGCCAGGT
CATCAACCAGGGCAAGGCCATGTCCAAGTCGCTGGGCAACGGTGTGGACCTGGGGCAGGAGATCGACCGCTACGGGGTTG
ACGCCGTCCGGCTGACCATGGTGTTTGCCGGGCCGCCGGAGGAAGACATCGACTGGGCAGACGTGTCCCCGGGGGCATCG
GTGAAGTTCCTCAACCGTGCCTACCGGGTGATGGCGGAGGCCGCAGCCGCCTCTGCACCGGGGGTGGACCCGGCCACCGG
CGACCTGGCGCTGCGGCGGATGACCCACCAGACCCTGGCGAAGGTTACCGAGGCCGTGGAAGCCCAGCGGTTCAACGTCG
CCATCGCGCGGATCATGGAACTCGTCACCGCTGCTCGCCGGGCGATCGACTCGGGCCCTGGCGCCGCCGACCCCGCGGTG
CGTGAAGCCGCTGAGGTGATTGCGATCACCTTGGGTCTGTTCGCTCCCTACGTCGCCGAGGAAGGCTGGGAGATGCTCGG
CCACACCGGATCGGTGTCGGTGGGCACCTGGCGGGAGCCCGACCCTGCGCTCCTGGTCCAGGAGAGCGTGACGTGCGTGG
TCCAGGTGGCCAGCAAGGTCCGCGACAAGCTGCAGGTCTCCCCGGACATTTCCGCGGAAGAGCTGGAGCGGCTGGCCCTC
GCCTCGGAGAAGGTCCAGAATCACATCGCCGGACGTGAGATCCGCAGGATCGTGGTCCGTGAGCCCAAACTGGTCAACAT
CGTGGTCGCCTAA

Protein sequence :
MTAVSGDQTTSGSYDVRALQEKWQARWAKENPFTASEDPADPRPRRYVLDMFPYPSGDLHMGHAEAFAIGDVIARYHFAR
GENVLHPIGWDSFGLPAENAAIKHNFHPAEWTYTNIETQAESFRRYAISLDWSRRLHTSDPEYYRWNQWFFLRFFERGLA
YRKDGLVNWCPKDQTVLANEQVIQGKCERCGTEVERRALNQWYFKITDYAQRLLDDMEQLEGKWPERVLTMQRNWIGRSE
GADVQFTIEGREEPVTVFTTRPDTLYGATFFVVAPDSPLADELCAPEQREAFEAYRTQVSKLSDIERQSTEREKTGVFLG
RYAINPVNGERIPVWAADYVLADYGHGAIMAVPAHDQRDLDFARKFNLPVRVVVDTGEPDPAETGIATPGEGTLINSGPL
NGLSKSEAIPRIIEILTERGTGKAAVNYRLRDWLVSRQRFWGTPIPIIHCPECGEVPVPDEELPVRLPDLRGAALAPKGV
SPLAAATDWVNVSCPRCGGPAKRDTDTMDTFVDSSWYFLRYCSPNLDTAPFDQEKVAKWGPIDQYVGGVEHAILHLLYSR
FFTKVLYDMGMVPFTEPFVRLLNQGQVINQGKAMSKSLGNGVDLGQEIDRYGVDAVRLTMVFAGPPEEDIDWADVSPGAS
VKFLNRAYRVMAEAAAASAPGVDPATGDLALRRMTHQTLAKVTEAVEAQRFNVAIARIMELVTAARRAIDSGPGAADPAV
REAAEVIAITLGLFAPYVAEEGWEMLGHTGSVSVGTWREPDPALLVQESVTCVVQVASKVRDKLQVSPDISAEELERLAL
ASEKVQNHIAGREIRRIVVREPKLVNIVVA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 3e-163 44