Gene Information

Name : Tfu_1179 (Tfu_1179)
Accession : YP_289240.1
Strain : Thermobifida fusca YX
Genome accession: NC_007333
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1374085 - 1375515 bp
Length : 1431 bp
Strand : +
Note : -

DNA sequence :
GTGTTACACGTGACACGTCGAGCAAAGATTGTCGCGACCCTTGGACCGGCTACCTCGAGCCCTGAAGTCCTCCGCAAGCT
CGTCGACGCCGGCCTGGACGTAGCGCGACTCAACCTCAGCCACGGTACCCACGACGACCACCAAACCATGTATCGCAACG
TCCGCGCCGCAGCGGAGGCCAGCGGACGTAATGTCGGTATTCTCGCCGACCTGCAAGGGCCGAAGATCCGTCTCGGGACG
TTCGTCGACGGATCCGTGACCCTCAGCCCCGGTGACGAGTTCACCATCACCATCGACGATGTACCCGGGGACCGCCACCG
GGTCTCCACCACATATAAAGGACTCCCTGGTGATGTCCGTCCTGGCGACCGCGTCCTCATCGACGACGGTCGCGTTGTTT
TGGAATGCGTCAAAAGCACCAGCACGGATGTCCACACCCGCGTCATCGTCGGCGGCCCGGTATCCAACCACAAAGGGCTC
AACCTGCCCGGGGTGTCGGTTGCGGTCCCCGCGCTGACCGAAAAAGACGAACGGGACCTGCGCTGGGCCCTGGAGCAGGG
CGTCGACATGGTGGCGCTCTCTTTTGTGCGCAGCCCCGCCGACGCGGAAGACGTCCACCGGGTCATGGACGAGATGGGCG
TGCACGTCCCCCTCATCGCCAAGATCGAAAAACCTCAGGCGGTGGAGCGGCTTCAGGACATCATCGAGGCTTTCGACGGC
GTCATGGTCGCCCGCGGCGACCTCGGTGTCGAACTCCCCCTCGAAAATGTGCCCATGGTGCAGAAACGCGCCATTGAACG
GTGCCGGGACAAAGCCAAACCGGTCATCGTCGCCACGCAGATGCTCGAATCCATGATCCACAACCCGCGCCCCACGCGGG
CTGAGGCTTCTGACGTGGCTAACGCCGTCCTCGACGGCGCGGACGCAGTCATGCTCTCCGGCGAGACCAGCGTCGGAAAG
TACCCCGTGGAGACCGTGCAGACCATGGCGCGGATCATCGCCGCCGCCGAACAGGAGTCCCTGCGCGCCTCCCACATCCT
CCACCGGGTCCCGGAGACCGTGGGCGGGTCGATCGCCCGAGCCGCTGCCGAAGTCGGAGCCACCGTGGGCGCCAAGGCCC
TTGTCGCCTTCACCAGCAGCGGGGAGACTGCACGCCGGCTCGCCCGCTACCGTTCCCCCATTCCGCTGCTGGCGTTCACC
ACCGAGCCTGCCACCCGCGCCCAGCTCTCCCTCACCTGGGGTGTGGAAACCCACCTCGTGCCGTGGGTGGACAACACCGA
CGACATGGTCCGCCAGGTCGAGAACGAACTCCTGGACATGGACTACCAGAAGGGCGACAAAGTCGTCATCGTCGCGGGAA
GCCCGCCTGGCACCCGAGGGTCGACCAACATGTTGCGCGTGCACCGTATGGGTGACGCCATCTCAAACTGA

Protein sequence :
MLHVTRRAKIVATLGPATSSPEVLRKLVDAGLDVARLNLSHGTHDDHQTMYRNVRAAAEASGRNVGILADLQGPKIRLGT
FVDGSVTLSPGDEFTITIDDVPGDRHRVSTTYKGLPGDVRPGDRVLIDDGRVVLECVKSTSTDVHTRVIVGGPVSNHKGL
NLPGVSVAVPALTEKDERDLRWALEQGVDMVALSFVRSPADAEDVHRVMDEMGVHVPLIAKIEKPQAVERLQDIIEAFDG
VMVARGDLGVELPLENVPMVQKRAIERCRDKAKPVIVATQMLESMIHNPRPTRAEASDVANAVLDGADAVMLSGETSVGK
YPVETVQTMARIIAAAEQESLRASHILHRVPETVGGSIARAAAEVGATVGAKALVAFTSSGETARRLARYRSPIPLLAFT
TEPATRAQLSLTWGVETHLVPWVDNTDDMVRQVENELLDMDYQKGDKVVIVAGSPPGTRGSTNMLRVHRMGDAISN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-80 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-80 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 8e-80 43
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 4e-66 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-79 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tfu_1179 YP_289240.1 pyruvate kinase VFG0479 Protein 2e-80 43