Gene Information

Name : nrdF (MHP7448_0223)
Accession : YP_287620.1
Strain : Mycoplasma hyopneumoniae 7448
Genome accession: NC_007332
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 263409 - 264428 bp
Length : 1020 bp
Strand : -
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
TTAAAAATAAAAAACGACTACTACCATCAATCAGTTTCGCCACTCGAATATGCGCTTAATAATTTTTCAGGAAAAATGCG
ATCAATCAACTGAAATATCATAAATGATCCAAAAGATCTTGAAGTTTGAACCCGAATAGTGCAAAATTTCTGAATTCCAG
AAAAAATTCCGCTTTCAAATGATCTTGAATCCTGAAGAACTTTATCACCTACCTGAAAAAAAGTAGTTACTCGCACTTTT
ACCGGACTTACTTTACTTGATACAATTCAGGCAACAATCGGTGATGTAGCCCAAATTAAACACTCTTTAACCGATCATGA
ACAGGTAATTTATACAAATTTCGCTTTTATGGTTGGGGTTCATGCTCGTTCTTATGGTTCAATTTTTTCTACCCTTTGCT
CAAGTGAAGAAATAGAAGAGGCGCATAACTGGGTAATCAATAACGAAAAATTGCAAAAAAGGGCCAGAATTCTTATACCT
TTTTATGTAGGTGAAGATCCTTTAAAATCAAAAGTTGCTGCTGCTTTAATGCCAGGTTTTCTCTTATATGGTGGTTTTTA
TCTTCCTTTTTATCTTTCAGCGCGTTCAAAACTGCCAAATACATCCGATATTATTCGACTGATTTTACGCGATAAAGTGA
TTCATAATTATTATTCAGGTTATAAATTTCAAAAAAAAGTGGAAAAATTAAGCCCGGAAAAACAAGACGAAATTAAAAAA
TTTACCTTTGATTTATTATATAAACTAATTGAATTAGAAAAAGATTATCTCTATGATTTATATTCTGAAGTTGGACTTGC
TGAATCAGCAATAAAATTTAGCATTTATAATGCCGGGAAATTCTTGCAAAATCTAGGATATGATTCACCTTTTTCAAAAG
AGGAAACCGAAATTGAACCTGAAATTTTTAGTCAATTATCGGCTCGAGCTGATGAAAATCATGACTTTTTTTCAGGAAAT
GGCTCTTCTTATGTAATGGCGCTTGCTGAAGAAACCGAAGATGAAGATTGGGAGTTTTAA

Protein sequence :
MKIKNDYYHQSVSPLEYALNNFSGKMRSINWNIINDPKDLEVWTRIVQNFWIPEKIPLSNDLESWRTLSPTWKKVVTRTF
TGLTLLDTIQATIGDVAQIKHSLTDHEQVIYTNFAFMVGVHARSYGSIFSTLCSSEEIEEAHNWVINNEKLQKRARILIP
FYVGEDPLKSKVAAALMPGFLLYGGFYLPFYLSARSKLPNTSDIIRLILRDKVIHNYYSGYKFQKKVEKLSPEKQDEIKK
FTFDLLYKLIELEKDYLYDLYSEVGLAESAIKFSIYNAGKFLQNLGYDSPFSKEETEIEPEIFSQLSARADENHDFFSGN
GSSYVMALAEETEDEDWEF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 1e-70 51