Gene Information

Name : thyA (Daro_0593)
Accession : YP_283820.1
Strain : Dechloromonas aromatica RCB
Genome accession: NC_007298
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 663441 - 664235 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCAGCCCTACCTCGACCTGATGCGCCACGTGCTGGACAACGGCAATGACAAATCCGACCGTACCGGCACTGGCACGCG
CTCCGTCTTCGGCTGGCAGATGCGCTTTGACCTGAGCCAGGGCTTCCCGGTGATGACGACCAAGAAGCTGCACCTGAAAT
CGATCATCCACGAACTGCTGTGGTTCATCCAGGGCGACACCAACATCAAGTACCTGCAGGAAAACGGCGTCAAGATCTGG
GACGAATGGGCCGATGAAAACGGCGATCTCGGCCCGGTCTACGGCAAGCAGTGGCGCCGCTGGGAAACGCCGGACGGCCG
CGTCATCGACCAGATCACGCAACTGGTCAACAGCCTGAAGAACAATCCGGATTCCCGCCGCCACATCGTCTCCGCCTGGA
ACCCCGGCGATGTGGACAACATGGCCCTGCCACCCTGCCACTGCCTTTTCCAGTTTTACGTCGCAAACGGCAAGCTGTCC
TGCCAGCTCTACCAGCGCAGCGCCGACATTTTCCTCGGCGTGCCATTCAACATCGCCTCCTATGCCCTGTTCACGATGAT
GCTGGCGCAGGTTTGCGGCTACCAGCCAGGCGAATTCGTCCATACCTTTGGCGACGCTCATCTTTACTCGAACCACTTCG
AGCAGGCAAAACTACAGCTTTCCCGCGACACCCGCCCCCTGCCAACCATGTGGATCAATCCGGAAGTGAAGGACCTGTTC
GCCTTCCGCTTCGAGGATTTCCGCCTCGAAGGCTACGACCCGCACCCGCACATCCCGGCCCCGGTGGCCGTTTAA

Protein sequence :
MQPYLDLMRHVLDNGNDKSDRTGTGTRSVFGWQMRFDLSQGFPVMTTKKLHLKSIIHELLWFIQGDTNIKYLQENGVKIW
DEWADENGDLGPVYGKQWRRWETPDGRVIDQITQLVNSLKNNPDSRRHIVSAWNPGDVDNMALPPCHCLFQFYVANGKLS
CQLYQRSADIFLGVPFNIASYALFTMMLAQVCGYQPGEFVHTFGDAHLYSNHFEQAKLQLSRDTRPLPTMWINPEVKDLF
AFRFEDFRLEGYDPHPHIPAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 6e-79 63