Gene Information

Name : lysS (Daro_2848)
Accession : YP_286048.1
Strain : Dechloromonas aromatica RCB
Genome accession: NC_007298
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 3065073 - 3066578 bp
Length : 1506 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCCAACGCCGAACAGCAAGCCCCGGTCCAGCAAGACGAAAACCAACTCATCGCAGAGCGCCGTGCCAAACTGGCCGA
GTGGCGCAAGACCGGGAAGGCTTTCCCGAATGATTTCCAGCGTGAGAACACCGCTGCCAAGGTCCTCGAAGGCTATGGCG
AGAAAACGGCGGAAGAGCTTGAAGGCCTGCCGATTGAAGTCAAGGTTGCCGGCCGCCTGATGCTCAAGCGCGTCATGGGC
AAGGCTTCCTTTGCCACCATTCAGGATCTGTCGGGCCGTATCCAGATCTACATCACCCGGGACCGCGTTGGTGAAGAGGT
CTATGCCGACTTCAAGACCTGGGACTTGGGCGACATCATTGGCGTCACCGGTAGCCTGATGAAGACCAAGACCGGCGAGC
TGTCGATTCAGGCCGCCGAAATCCGCCTGCTGACCAAGTCGCTGCGCCCGCTGCCGGACAAGTTCCACGGCCTGGCCGAT
CAGGAAATGAAGTATCGCCAGCGCTATGTCGACCTGATCATGAACGAGGAAACGCGCTTCACCTTCCGCGCCCGTTCGGC
CATCGTTGCCTCTATCCGCAACTACATGACCGGCCATGGCTTCATGGAAGTCGAAACGCCGATGATGCACCCGATCCCGG
GCGGTGCCTCGGCCAAGCCGTTTGTCACGCACCACAACGCGCTCGACATGCAGCAGTTCCTGCGCATCGCGCCGGAGCTG
TACCTGAAGCGCCTGGTCGTCGGCGGTTTCGAGAAGGTTTTCGAAATCAACCGCAATTTCCGCAATGAAGGTCTCTCGCC
GCGCCACAACCCCGAATTCACGATGATGGAGTTCTACGAGGCCTACGCGAACTACCACACGCTGATGGACTTCACCGAAG
GCCTGCTCCGCCACGCCGCCCGCGAGGCACTGGGCAAGGAAGTCTTCGTCTATCAGGGCCGCGAACTGGACCTCTCCAAG
CCTTTCCATCGCCTTACCATCAACCAGGCCATCCAGCGCCAGCATCCGGAATTTAGTGATGCCGAGCTGGCCGATCCGGA
ATTCCTGAAAGCCAAGATCAAACACTTCGGTGAGCCGCTCAAGCCGGGCGGTCTGGGCAGCCTGCAACTGCAACTGTTCG
AAGCCTGCGCCGAAGCCCACTGCTGGGAGCCGACTTTCATCATCGACTACCCGGTCGAAGTGTCCCCGCTGGCCCGTGCC
TCGGACACCAACCCGGAAATCACCGAGCGTTTTGAGCTGTTCATCGTTGGGCGTGAAATCGCCAACGGGTTCTCGGAGTT
GAATGATGCCGAAGATCAGGCAGCGCGCTTCCAGGAACAGATGAAAGCGAAGGATGCCGGCGACGAGGAAGCGATGTATT
ACGACGCCGATTTCATTCGCGCGCTGGAATATGGCCTGCCGCCGACCGGTGGCTGTGGCATCGGCATTGATCGCCTGATC
ATGCTGCTGACCGACGCCGCCGCGATTCGGGATGTCATCCTATTCCCCTCCATGCGCCCCGAATGA

Protein sequence :
MSNAEQQAPVQQDENQLIAERRAKLAEWRKTGKAFPNDFQRENTAAKVLEGYGEKTAEELEGLPIEVKVAGRLMLKRVMG
KASFATIQDLSGRIQIYITRDRVGEEVYADFKTWDLGDIIGVTGSLMKTKTGELSIQAAEIRLLTKSLRPLPDKFHGLAD
QEMKYRQRYVDLIMNEETRFTFRARSAIVASIRNYMTGHGFMEVETPMMHPIPGGASAKPFVTHHNALDMQQFLRIAPEL
YLKRLVVGGFEKVFEINRNFRNEGLSPRHNPEFTMMEFYEAYANYHTLMDFTEGLLRHAAREALGKEVFVYQGRELDLSK
PFHRLTINQAIQRQHPEFSDAELADPEFLKAKIKHFGEPLKPGGLGSLQLQLFEACAEAHCWEPTFIIDYPVEVSPLARA
SDTNPEITERFELFIVGREIANGFSELNDAEDQAARFQEQMKAKDAGDEEAMYYDADFIRALEYGLPPTGGCGIGIDRLI
MLLTDAAAIRDVILFPSMRPE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 4e-136 59

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_286048.1 lysyl-tRNA synthetase VFG1668 Protein 2e-136 59