Gene Information

Name : Daro_2257 (Daro_2257)
Accession : YP_285464.1
Strain : Dechloromonas aromatica RCB
Genome accession: NC_007298
Putative virulence/resistance : Resistance
Product : ATPase, E1-E2 type:heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase:heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 2442707 - 2444938 bp
Length : 2232 bp
Strand : +
Note : -

DNA sequence :
ATGTCCGTTCGCCCAGAAGAAATTGCGCCCAAGCGTGACGCATGTGACCACGATCATGGCCGGAAGTGCTGTGCAGGTGA
TTCGTCGCAAGCGACGCCCGCTGATGAAGTCAGCCTGGTTACCAGTGACATCCCGATGGGATCGACGCTGACCCGCCTCC
GCATTGCTCAGATGGATTGTCCGACCGAGGAGGCTTTGATTCGCAAAAAGCTTGGCGGCATGGCTGCCGTGCAAGGACTG
GAGTTCAATTTGATGCAGCGAGTGTTGTCTGTGGTGCATGACAACGACGCTTTAGCCGCTGTTGAAGCGGCCATCCGGGA
ATTAGGGATGTCCTCCGAGCCCATGCAGGTGGCAGCTTCGGCGACACCGACTGAGCAGATCGACAAGCCTTGGTGGCCGT
TGGCGCTGGCAGGCGTGGCTGCACTATCAGCGGAAATAGTGCATTGGGTCAGTATGCCGGAATGGGTATCGGCGCTGCTG
GCGCTCATCGCCATCGCCATCGGTGGGATCGGCACTTACCAAAAGGGGTGGATTGCGTTGCGCCACGGCAATCTCAATAT
CAATGCCCTGATGAGCATCGCTGTCACTGGTGCGGTACTGCTGAGGCAATGGCCGGAAGCGGCAATGGTCATGGTCTTGT
TCTCACTTGCCGAATTGATCGAAGCAAAGTCGCTGGATCGGGCACGTAACGCCATTCGCAGCCTGGTACAACTCACGCCT
GAACAGGCGACCGTTCAACAGACAAATGGCGATTGGATGGATATGTCGGCCAAAGCTGTTGCTATAGGCCAAATTGTCCG
AGTCAAACCGGGGGAACGAATCGCACTTGATGGCGTGCTGACAACCGGCCGGTCGACCGTCAATCAAGCGCCGATTACCG
GAGAAAGCATGCCGGTCGAGAAAGCGATCGGTGACAGTGTGTTCGCTGGAACGATCAACGAGTCCGGTTCGTTCGAATAC
CGGGTCACCGCCGAGTCTACACAATCAACCCTGGCGCGCATCATTCATGCTGTTGAGGAAGCCCAAGGCGCACGGGCTCC
GACCCAGCGCTTTGTTGATCAGTTCGCCAAAATCTACACACCGGCAGTGTTCGCTTTCGCATTGGCGGTGGCCCTTGTGC
CACCATTGATGCTTGATGGCAGTTGGCACGATTGGATCTACCGTGCGCTGGTGTTGCTGGTTATCGCTTGTCCATGCGCC
CTGGTCATTTCGACACCTGTCACCATCGTCAGCGGCCTGGCTGCCGCAGCGCGCCACGGCATTCTGATCAAGGGCGGGGT
ATATCTCGAAGAAGGTCACAAACTCGCGTGGCTGGCATTCGACAAGACCGGCACCATCACGCACGGCAAACCTGCGTTAA
CCGATACCGTCCTGTTGGATCAGCCGGCCGGACTAGAGGCCGTTCGAATTGCCACCAGCCTTGCCGCACGCTCTGACCAT
CCCGTTTCTCGCGCCATTGCGTTAGCCGGGGAGCAGAACAATACCAACCTGCTTGAGGTGGCAGACTTCTCCGCCATTCC
AGGACGAGGCGTTCGTGGAACCGTTGGCGGGGTCAATTATCAGCTTGGCAACCATCGCTTAATCCATGAGCTTGGCGTAT
GTACCCCAACGCTGGAGGCACAACTCGGCGAACTGGAAGAGCAAGGGAAGACGGTCATTCTCCTTACTGATAGCGAGCGG
GTGCTGGTGCTGTTCGCCGTGGCCGATACGGTGAAAGAGAGCAGCCTTTCAGCGATCAAAGCGCTGCACGAGTTGGGTAT
CAAGACGGTCATGCTGACCGGTGATAACGCGCATACGGCACGGGCCATTGCGACGCAAGTACAAATCGACGAAGCCTTGG
GCGACCAATTGCCGGAGGACAAACTGCGCGCTATTGAGCGATACGCCCTGCGCGGTAAAGTGGGCATGGTGGGTGACGGC
ATCAATGACGCTCCCGCTTTAGCGCGAGCCGACATAGGCTTTGCCATGGGGGCTGCCGGCACCGATACCGCCATCGAAAC
CGCTGACGTGGCGCTGATGGACGATGACCTCAATAAAATTGCGCGGTTCGTTCGCCTGTCTCGTACCACCCGAACAGTGC
TGGTTCAGAACATCACGCTGGCATTGAGCATCAAGGCAATCTTTTTGGTACTCACGATGTTGGGTATGGGCACCATGTGG
ATGGCGGTTTTTGCGGATATGGGTGCGAGTCTGTTGGTCGTGGCTAATGGACTAAGGCTTGTCCGTCAGTAG

Protein sequence :
MSVRPEEIAPKRDACDHDHGRKCCAGDSSQATPADEVSLVTSDIPMGSTLTRLRIAQMDCPTEEALIRKKLGGMAAVQGL
EFNLMQRVLSVVHDNDALAAVEAAIRELGMSSEPMQVAASATPTEQIDKPWWPLALAGVAALSAEIVHWVSMPEWVSALL
ALIAIAIGGIGTYQKGWIALRHGNLNINALMSIAVTGAVLLRQWPEAAMVMVLFSLAELIEAKSLDRARNAIRSLVQLTP
EQATVQQTNGDWMDMSAKAVAIGQIVRVKPGERIALDGVLTTGRSTVNQAPITGESMPVEKAIGDSVFAGTINESGSFEY
RVTAESTQSTLARIIHAVEEAQGARAPTQRFVDQFAKIYTPAVFAFALAVALVPPLMLDGSWHDWIYRALVLLVIACPCA
LVISTPVTIVSGLAAAARHGILIKGGVYLEEGHKLAWLAFDKTGTITHGKPALTDTVLLDQPAGLEAVRIATSLAARSDH
PVSRAIALAGEQNNTNLLEVADFSAIPGRGVRGTVGGVNYQLGNHRLIHELGVCTPTLEAQLGELEEQGKTVILLTDSER
VLVLFAVADTVKESSLSAIKALHELGIKTVMLTGDNAHTARAIATQVQIDEALGDQLPEDKLRAIERYALRGKVGMVGDG
INDAPALARADIGFAMGAAGTDTAIETADVALMDDDLNKIARFVRLSRTTRTVLVQNITLALSIKAIFLVLTMLGMGTMW
MAVFADMGASLLVVANGLRLVRQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 0.0 66
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 6e-112 49
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 7e-112 49
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 7e-109 48

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Daro_2257 YP_285464.1 ATPase, E1-E2 type:heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase:heavy metal translocating P-type ATPase BAC0298 Protein 0.0 69
Daro_2257 YP_285464.1 ATPase, E1-E2 type:heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase:heavy metal translocating P-type ATPase BAC0455 Protein 1e-87 41