Gene Information

Name : metB (M5005_Spy_0146)
Accession : YP_281510.1
Strain : Streptococcus pyogenes MGAS5005
Genome accession: NC_007297
Putative virulence/resistance : Unknown
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.8
Position : 156335 - 157525 bp
Length : 1191 bp
Strand : +
Note : -

DNA sequence :
TTGTCTAAAAGAGAGTTCATTGGAGTTAACGCTATTGCGGAGGTGCACGAAATGAGAGAAAATACGACCTTATTACATGG
CTATACGGTTATTGACGAGTTTACAGGAGCAGCTTCAGTTCCCATCTATCAGACTTCGACGTTCCACAATTCAGAACTGT
ATTGTCCTAGTCAAAAACATTTGTACACACGCTTTTCAAACCCAACGACTGAAGCTTTAGAAGACGGGTTAGCCTGTTTA
GAAAAAGCGACTTATGCGGTGGCTTATGCATCTGGTATGGCTGCTATTTCAACTGTTTTGATGCTCTTAAAAGCTGGAGA
TCATGTGATTTTCCCATTGGAGGTCTATGGAGGGACTTGTCAATTTGCGACAGCTATTTTACCCAATTATCAGATTGAAA
CAAGCTTTGTAGATATGGCTGATTTAGCAACAGTAAAAGCAAGTATCAGGCCTAATACGCGTATGATTTATCTAGAGACA
CCGTCAAATCCGCTCTTGAAAATTTGTGATATTTCAGAGCTTGCGCAACTCGCCAAAGCTTATGGTGTGCTAACTGTGGC
TGATAATACCTTTATGACCAGTTTGTATCAAGAACCCTTAGCTATGGGTGTGGATATTGTAGTAGAAAGTGTGACCAAAT
TTATCAATGGTCATAGTGATGTGGTAGCTGGTTTAGCTGCTACCAATAATGAGGCTATCTACAACCAGCTCAAGCTTTTT
CAAAAAAACTTTGGAGCAATTGTTGGGGTCGAAGACGCTTGGCTGATTCTTCGTGGCATGAAAACTATGGGGATCCGTAT
GGAACAAGCGGTAAAAAATGCTCAGCAGCTCGCTAACTATTTAGCGAAGCACCCCAAAGTTCTTAAGGTACATTACCCTG
GCTTAGACAGTCATCCTAATCACGATACCCACCTGCAACAAGCTAAGAATGGTGGTGCTGTTTTATCCTTTGAGTTGGCT
TCTAAGGAGGAGCTGATGTCCTTTACCCATCGTATTCAGTTGCCGATTTTAGCCGTTAGTCTAGGTGGAGTAGAGTCCAT
TTTGTCACATCCAGCAACGATGTCTCATGCTTGTTTATCGTCACAAGCGCGGTTGGAACAAGGGGTTGTTGATGGTTTGC
TGCGCTTGTCTTGTGGTGTTGAAAATATCGAAGACTTATTGGCCGATTTTGAGCAAGCACTTGCTTTTTAA

Protein sequence :
MSKREFIGVNAIAEVHEMRENTTLLHGYTVIDEFTGAASVPIYQTSTFHNSELYCPSQKHLYTRFSNPTTEALEDGLACL
EKATYAVAYASGMAAISTVLMLLKAGDHVIFPLEVYGGTCQFATAILPNYQIETSFVDMADLATVKASIRPNTRMIYLET
PSNPLLKICDISELAQLAKAYGVLTVADNTFMTSLYQEPLAMGVDIVVESVTKFINGHSDVVAGLAATNNEAIYNQLKLF
QKNFGAIVGVEDAWLILRGMKTMGIRMEQAVKNAQQLANYLAKHPKVLKVHYPGLDSHPNHDTHLQQAKNGGAVLSFELA
SKEELMSFTHRIQLPILAVSLGGVESILSHPATMSHACLSSQARLEQGVVDGLLRLSCGVENIEDLLADFEQALAF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 0.0 100
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-77 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-77 43