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Name : clpC (M5005_Spy_1763) Accession : YP_283126.1 Strain : Streptococcus pyogenes MGAS5005 Genome accession: NC_007297 Putative virulence/resistance : Virulence Product : negative regulator of genetic competence Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0542 EC number : - Position : 1723060 - 1725504 bp Length : 2445 bp Strand : - Note : - DNA sequence : ATGATTATGTATTCAACGAAGATGCAAGACATTTTTAGACAGGCGCAGTTCCAAGCTGCTCGCTTTGATAGCCATTGCCT GGAAACTTGGCATGTTTTGTTAGCTATGGTAGCTGTAGATAATTCTTTAGCAAATATGATTTTAAGTGAATATGATGCCC AAGTCGCCATAGAAGAATATGAAGCTGCAGCTATTTTAGCCATGGGCAAAACCCCTAAAGAACAGTTGTCTCGTGTAGAC TTCAGACCTCAATCTAAAACTTTGACTAACTTGTTAGCTTTTGCGCAGGCTATTAGCCAAATCACTAGGGATCAAGAAGT CGGCTCTGAGCATGTCTTATTTGCTATTTTATTGAATCCAGATATTATGGCGAGTCGTTTGTTAGAAATAGCTGGCTATC AGATAAAAGATAACGGCAATGGGCAGCCGCGATTAGCTGACTTGCGAAAAGCAATAGAACGTCATGCAGGTTACAGTAAG GAAATGATCAAGGCTATTCACGAACTACGTAAGCCTAAAAAAACGAAAACACAAGGGACCTTTTCAGATATGATGAAGCC ACCAAGTACAGCTGGTGAGTTGAGTGATTTCACAAGAGATTTGACTGAAATGGCAAGACAAGGTTTGTTAGAATCGGTGA TTGGACGTGACCAAGAAGTATCTCGTATGATTCAGGTACTAAGTCGTAAAACGAAAAACAATCCTGTCTTGGTAGGTGAT GCAGGTGTTGGTAAAACTGCGCTTGCTTATGGCCTTGCTCAACGGATTGCAAATGGCGCTATTCCTTATGAACTTAAGGA GATGCGTGTCCTAGAATTAGACATGATGAGTGTGGTAGCAGGAACCCGTTTTCGTGGGGATTTTGAAGAGCGCATGAATC AAATCATTGATGATATTGAAGCTGATGGTCAGATTATTCTTTTTGTTGATGAACTACATACTATTATGGGTTCTGGCAGT GGTATTGACAGTACACTTGATGCGGCTAACATTTTAAAACCAGCATTATCGCGCGGCACTCTTCATATGGTTGGAGCAAC AACTCAAGAAGAATACCAAAAACATATTGAAAAAGATGCAGCTCTTTCGCGTCGTTTTGCTAAAATATTAATTGAAGAAC CTAATACAGAAGATGCTTATCAGATTTTGATGGGCCTAAAATTATCTTATGAGACCTACCATAATGTCTCGATATCAAAT GAGGCAGTTAAAACAGCTGTAAAAATGGCACACCGTTATTTAACCAGTAAAAATCTCCCTGATTCAGCTATCGATTTACT AGATGAAGCTAGTGCTGCTGTGCAAAACATGGTGAAAAAATCAGCACCTGAGACTTTAACACCAATAGACCAAGCTCTTA TCAATGGTGATATGAAAAAAGTATCTCGCCTCTTAGCTAAAGAAGCAAAAGGTCAGATGAGAAAACCAACACCGGTGACA GAAGATGATATTTTGGCAACCTTGAGTAAGTTATCGGGAATTCCACTTGAAAAACTGACGCAAGCTGATAGTAAAAAATA CCTCAATTTAGAAAAAGAACTGCATAAGCGTGTGATTGGTCAGGATGCTGCTGTTACGGCTATTTCAAGAGCCATTCGTC GTAATCAGTCAGGTATTCGAACAGGAAAACGTCCTATTGGATCATTTATGTTTCTTGGCCCAACAGGAGTAGGTAAGACA GAACTAGCAAAGGCCCTTGCAGAAGTTCTCTTTGATGATGAAGCAGCGCTTATTCGTTTTGATATGTCTGAGTACATGGA AAAATTCGCAGCGTCTAGGCTTAATGGAGCACCTCCTGGTTATGTCGGCTATGATGAAGGAGGTGAACTGACACAGAAAG TTAGAAATAAACCTTATTCAGTCTTGCTTTTTGATGAAGTGGAAAAAGCACATCCTGATATTTTTAACGTTCTCCTTCAA GTATTAGATGATGGTATATTGACTGATAGTCGTGGGCGTAAGGTCGATTTTTCAAATACTATTATTATCATGACCAGCAA TCTTGGCGCAACAGCCCTGCGCGATGATAAAACGGTCGGTTTTGGGGTCAAAGACATTCACCAAGACCATCAAGCTATGG AGAAACGTATTTTAGAAGAATTAAGAAAAACTTACCGCCCAGAATTTATCAATCGTATTGATGAAAAAGTGGTCTTTCAT AGTCTGACCCAAGATAACATGCGCGATGTGGTTAAAATCATGGTACAGCCCCTGATTACTACATTGGCAGAAAAAGGTAT TACCCTTAAAATTCAGCCTTTGGCCTTGAAACATTTGTCCGAGGTCGGCTATGATGAGCATATGGGGGCAAGACCATTAC GTCGAACGCTGCAAACTGAGATAGAAGATAAGCTATCAGAGCTTATTCTTTCTCGAGAATTGACAAGTGGGCATACGCTA AAAATTGGATTATCACATGGCAAATTAACGTTTCACATAGCTTAA Protein sequence : MIMYSTKMQDIFRQAQFQAARFDSHCLETWHVLLAMVAVDNSLANMILSEYDAQVAIEEYEAAAILAMGKTPKEQLSRVD FRPQSKTLTNLLAFAQAISQITRDQEVGSEHVLFAILLNPDIMASRLLEIAGYQIKDNGNGQPRLADLRKAIERHAGYSK EMIKAIHELRKPKKTKTQGTFSDMMKPPSTAGELSDFTRDLTEMARQGLLESVIGRDQEVSRMIQVLSRKTKNNPVLVGD AGVGKTALAYGLAQRIANGAIPYELKEMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIEADGQIILFVDELHTIMGSGS GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNTEDAYQILMGLKLSYETYHNVSISN EAVKTAVKMAHRYLTSKNLPDSAIDLLDEASAAVQNMVKKSAPETLTPIDQALINGDMKKVSRLLAKEAKGQMRKPTPVT EDDILATLSKLSGIPLEKLTQADSKKYLNLEKELHKRVIGQDAAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKT ELAKALAEVLFDDEAALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTQKVRNKPYSVLLFDEVEKAHPDIFNVLLQ VLDDGILTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGVKDIHQDHQAMEKRILEELRKTYRPEFINRIDEKVVFH SLTQDNMRDVVKIMVQPLITTLAEKGITLKIQPLALKHLSEVGYDEHMGARPLRRTLQTEIEDKLSELILSRELTSGHTL KIGLSHGKLTFHIA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| clpC | YP_005163377.1 | ATP-dependent Clp protease ATP-binding subunit | Not tested | Not named | Protein | 3e-151 | 47 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| clpC | YP_283126.1 | negative regulator of genetic competence | VFG0079 | Protein | 8e-169 | 44 |
| clpC | YP_283126.1 | negative regulator of genetic competence | VFG0080 | Protein | 2e-135 | 42 |
