Gene Information

Name : ulaA (M5005_Spy_1662)
Accession : YP_283025.1
Strain : Streptococcus pyogenes MGAS5005
Genome accession: NC_007297
Putative virulence/resistance : Virulence
Product : PTS system ascorbate-specific transporter subunit IIC
Function : -
COG functional category : S : Function unknown
COG ID : COG3037
EC number : -
Position : 1618587 - 1619822 bp
Length : 1236 bp
Strand : -
Note : membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr

DNA sequence :
ATGGAAGCATTATTATCATTTATTCGAGATATTTTAAAAGAACCTGCATTTTTAATGGGCTTGATTGCCTTTGCAGGGTT
GGTGGCTTTGAAAACACCTGCTCATAAGGTGTTGACAGGAACCTTGGGGCCGATTTTGGGATACCTTATGCTTGTTGCAG
GGGCGGGTGTTATTGTGACCAATTTGGACCCTCTTGCCAAACTCATTGAGCACGGTTTTAGCATCACTGGCGTAGTGCCA
AATAACGAAGCCGTCACTTCTGTCGCTCAAAAGATTCTGGGTGTGGAAACTATGTCCATCTTGGTGGTTGGGTTATTGCT
CAATTTGGCTTTTGCTCGTTTTACCCGCTTCAAATACATTTTCTTAACAGGACATCACAGCTTCTTTATGGCTTGTCTCT
TGTCCGCCGTGCTTGGAGCTGTTGGTTTCAAAGGAAGTCTTTTGATTATCTTAGATGGGTTCCTCTTGGGAGCTTGGTCA
GCTATTTCGCCAGCCATTGGTCAACAGTATACTCTGAAAGTGACTGACGGAGATGAAATCGCTATGGGACACTTTGGTAG
TTTGGGCTATTACCTTTCTGCCTGGGTTGGTAGCAAGGTTGGCAAAGACAGTAAAGATACCGAAGACCTTCAGATTTCTG
AAAAATGGAGTTTCTTGCGCAACACCACCATTTCAACAGGACTTATCATGGTGATTTTCTACTTGGTGGCAACAGTGGCT
TCTGTTTTGAGGAATGCTTCAGTAGCAGAAGAATTAGCAGCAGGTCAAAACCCATTTATTTTTGCCATTAAGAGTGGTCT
TACCTTTGCGGTTGGTGTGGCAATTGTCTACGCCGGTGTTCGCATGATTTTGGCTGACTTGATTCCAGCCTTCCAAGGTA
TTGCTAACAAATTAATTCCAAATGCTATTCCAGCCGTGGATTGTGCGGTATTCTTCCCTTATGCGCCAACCGCTGTTATC
ATCGGTTTTGCGTCAAGTTTCGTTGGTGGCTTACTTGGGATGTTGATTTTAGGAGTTGCAGGTGGTGTCCTGATTATCCC
AGGTATGGTGCCTCATTTCTTCTGCGGTGCAACAGCAGAGATTTTTGGAAATTCAACAGGTGGTCGTCGCGGTGCGATGA
TTGGTGCTTCGCTAATGGCTTATTACTCGCCTTCTTGCCAGCCATGCTTCTACCTGTACTTGGTAAACTTGGTTTTTCAA
ACACGACCTTTGGAGATGTGGATTTCGGTGTTTTAG

Protein sequence :
MEALLSFIRDILKEPAFLMGLIAFAGLVALKTPAHKVLTGTLGPILGYLMLVAGAGVIVTNLDPLAKLIEHGFSITGVVP
NNEAVTSVAQKILGVETMSILVVGLLLNLAFARFTRFKYIFLTGHHSFFMACLLSAVLGAVGFKGSLLIILDGFLLGAWS
AISPAIGQQYTLKVTDGDEIAMGHFGSLGYYLSAWVGSKVGKDSKDTEDLQISEKWSFLRNTTISTGLIMVIFYLVATVA
SVLRNASVAEELAAGQNPFIFAIKSGLTFAVGVAIVYAGVRMILADLIPAFQGIANKLIPNAIPAVDCAVFFPYAPTAVI
IGFASSFVGGLLGMLILGVAGGVLIIPGMVPHFFCGATAEIFGNSTGGRRGAMIGASLMAYYSPSCQPCFYLYLVNLVFQ
TRPLEMWISVF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF8 AAK27335.1 unknown Not tested PAI-I AL862 Protein 7e-73 47
unnamed CAC39291.1 hypothetical protein Not tested LPA Protein 6e-73 47
vpeC ADD91725.1 putative PTS system-specific IIC component VpeC Virulence PAI-I AL862 Protein 6e-73 47