Gene Information

Name : M5005_Spy_1450 (M5005_Spy_1450)
Accession : YP_282813.1
Strain : Streptococcus pyogenes MGAS5005
Genome accession: NC_007297
Putative virulence/resistance : Unknown
Product : phage-encoded DNA polymerase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 1416408 - 1418330 bp
Length : 1923 bp
Strand : -
Note : -

DNA sequence :
ATGAGACATTTAAATATTGATATTGAAACCTATAGTTCGAATGACATCAAAAATGGGGTTTACAAGTACGCTGACGCTGA
AGATTTTGAGATTTTACTTTTCGCTTACTCTATAGATGGCGGAGAAGTAGAGTGCCTTGATTTGACAAGGCAGTCTCTAC
CTGAAGACATCAAAGATATGTTATTTGATGATAAAGTCCGAAAGCACGCCTTTAATGCCCAATTCGAAAGAGTTTGTCTC
AGTCGTTACCTCGGCCTACCTTACTATTTAGATCCCGCACAATGGCAGTGTACGATGGTACTTGCACAAGAGCTGGGTCT
GCCTGCAAGCCTGGAAAAATGTGCGCTGTATTTAAAATTAGCGCAAGAAAAAGACGCAGCAGGTAAAAATCTCATTAAAT
ATTTTTCGGTACCCTGCAAGCCTACAAAAGCCAACGGGGGAAGAACGAGGAACCTGCCCGAGCATGATCCTGGAAAATGG
CAAATGTTTATTAACTACTGTATGCAAGACGTTGTTGTTGAGATGGCAATTGCCGAAAAACTAGAGTCAGTTCCTGTGCA
CGACCGTGAGTGGGATTACTACGTCTGCGACCAGAGAATCAACGACAGAGGCGTGGCACTTGATAAAGAGTTAGTTGCTT
CGGCTTTGTATTGTAAAGATGTTAAGATGGAAAGTTTGTCTGGTGAACTAAAGGCTCTAACAGGACTTGATAATCCTAAT
AGCAGGGCGCAGCTGCTACCGTGGCTAAAAGAACACGGTTATTCGGCTAATGGGCTGACTAAAGCTGATGTTGAACAGGA
ACTTAAGAAGGCCGAAGGAGAGCTTAAGAGAGTTTTAGAACTTAAACTACAAACCGCGATGTCAAGTCTAAAAAAATATG
AAGCTATGGAAAGAGCTATGTGCTCAGACGGACGAGTTCATGGGCTACTTCAGTTTTACGGGGCTAGCCGGACAGGAAGA
TGGGCGGGCAGAGTTGTCCAAGTACAGAACTTAGCTAGGAATTATATAAAGGATCTAGATGATGCTAGAGAGTATGTTAA
AAAGCGTGATATTGATGCTGTGGAGATTTTATACGATAGCCTTAACGACACTTTAAAGCAGCTCGTGCGAACGGCACTCG
TGGCTAAAGATGGCTATACCTTCTATGTCTCTGACTTCTCGGCGATTGAGGCTAGGGTGATTGCATGGTTTGCTGGAGAG
CAGTGGAGGCTTGACGTGTTTTCTACGCACGGGAAAATCTACGAGGCGTCTGCCAGTCAGATGTTCGGAATTCCAATTGA
GGAGATTGACAAGGAACTACGCCAAAAGGGCAAAATTTCAGAGTTAGCACTTGGCTATCAAGGAGGTCCTGGAGCGCTTA
AGCAGATGGGGGCTCTAAATATGGGAGTCAAGGAAGAGGAGCTTCAAGGGTTAGTTGATGACTGGCGCAGGGCCAATAAG
AAAATCGTCCAATTTTGGAAAGACGTACAAAGAGCCGCCATCAAAGCCATCAAATCGAGAGCACCGATAAAACTTGGAAA
AATACGATTTAGATACCGGAAAGGTTTCCTCTTTATAACATTGCCTAGCGGTAGGAACTTAGCTTATGCAAGAGCCAAGG
TTGAGCCAGGCGACTATGGAGACAAAATCATCTATGAGGGCCAAGGAGATAGGGCCTATTTCACAGCGCAAGAGACGTAC
GGCGGTAAGCTTGTCGAAAATATCGTTCAGGCGACGGCCAGGGATATTCTAGCTGAAGCGCTTCTGAGGATTGAAGCTGC
AGGCTATGATGTTGTTTTCCACGTTCATGATGAGGCTATTATCGAAGGTTCAGGCCTGATAATCGAAGAGGTTAATGATT
TGATGGCTCAGGCTCCTGAATGGGCGGAGGGTCTTCCTTTAAATAGCGAAGGCTATGTAACAAAGTATTATATGAAGGAT
TAG

Protein sequence :
MRHLNIDIETYSSNDIKNGVYKYADAEDFEILLFAYSIDGGEVECLDLTRQSLPEDIKDMLFDDKVRKHAFNAQFERVCL
SRYLGLPYYLDPAQWQCTMVLAQELGLPASLEKCALYLKLAQEKDAAGKNLIKYFSVPCKPTKANGGRTRNLPEHDPGKW
QMFINYCMQDVVVEMAIAEKLESVPVHDREWDYYVCDQRINDRGVALDKELVASALYCKDVKMESLSGELKALTGLDNPN
SRAQLLPWLKEHGYSANGLTKADVEQELKKAEGELKRVLELKLQTAMSSLKKYEAMERAMCSDGRVHGLLQFYGASRTGR
WAGRVVQVQNLARNYIKDLDDAREYVKKRDIDAVEILYDSLNDTLKQLVRTALVAKDGYTFYVSDFSAIEARVIAWFAGE
QWRLDVFSTHGKIYEASASQMFGIPIEEIDKELRQKGKISELALGYQGGPGALKQMGALNMGVKEEELQGLVDDWRRANK
KIVQFWKDVQRAAIKAIKSRAPIKLGKIRFRYRKGFLFITLPSGRNLAYARAKVEPGDYGDKIIYEGQGDRAYFTAQETY
GGKLVENIVQATARDILAEALLRIEAAGYDVVFHVHDEAIIEGSGLIIEEVNDLMAQAPEWAEGLPLNSEGYVTKYYMKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SEQ_2073 YP_002747288.1 phage DNA polymerase Not tested ¥ÕSeq4 Protein 0.0 97
polA YP_494120.1 phage related DNA polymerase family A Not tested ¥ÕSa2 Protein 3e-158 55
MW1425 NP_646242.1 DNA polymerase Not tested ¥ÕSa2 Protein 3e-159 55