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Name : tkt (M5005_Spy_1375) Accession : YP_282738.1 Strain : Streptococcus pyogenes MGAS5005 Genome accession: NC_007297 Putative virulence/resistance : Unknown Product : transketolase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0021 EC number : 2.2.1.1 Position : 1344931 - 1346916 bp Length : 1986 bp Strand : - Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo DNA sequence : ATGACATTTGATGCAATTGACCAGTTGGCAGTAAACACTGTCCGCACCCTATCAATGGATGCCATTCAAGCGGCAAATTC TGGACACCCAGGACTTCCAATGGGGGCAGCACCTATGGCCTATGTTCTTTGGAATCACTTCATGAACATCAATCCCAAAA CAAGCCGTAATTGGTCAAACAGAGACCGTTTTATCCTATCAGCAGGTCATGGAAGTGCCATGCTTTATAGCTTGTTACAC TTAGCTGGTTATGATTTATCTGTAGAAGATTTAAAGAACTTCCGTCAATGGGGTTCTAAAACACCAGGTCACCCAGAAGT GAACCACACAGACGGTGTCGAAGCAACCACAGGACCTCTTGGTCAAGGGATCGCAAATGCCGTTGGGATGGCCATGGCAG AAGCTCATCTAGCAGCTAAATTTAACAAACCAGGCTTTGACATCGTTGATCACTACACATTTGCTTTGAATGGTGACGGT GACCTTATGGAAGGGGTCAGCCAAGAAGCAGCAAGTATGGCAGGACATTTAAAACTTGGGAAATTGGTCTTGCTATATGA TTCAAACGACATCTCTCTTGATGGTCCAACCTCTATGGCTTTCACAGAAGATGTGAAAGGACGTTTCGAAGCTTATGGTT GGCAACATATCCTTGTGAAAGATGGAAATGATTTAGAAGAAATTGCAGCTGCTATTGAAGCAGCTAAAGCTGAAACTGAG AAACCAACCATCATCGAAGTCAAAACCATTATTGGTTTTGGTGCCGAAAAACAAGGAACTTCAGCTGTTCACGGCGCTCC TCTTGGAGCAGAAGGCATTGCTTTTGCCAAAAAAGCTTACCAATGGACTCATCAAGATTTTGAAGTGCCTGCTGAAGTAA CAGAGCGCTTTGCTCAAGGTCTTCAAGCGCGTGGTGAAAAAGCAGAACAAGCCTGGAATGACTTGTTTGCAGCTTATGAA GCAGAATATCCAGAATTAGCAGCAGAATACCAAAAAGCCTTTACTAACGAAGCTGCTCAAGTAGAACTTGAAGCGCACGA ACTTGGTAGTTCAATGGCGAGTCGTGTATCCAGTCAACAAGCCATCCAACAAATTTCAGAACAAGTAGCCTCTTTCTGGG GTGGGTCAGCAGACCTTTCAGCTTCAAACAATACTATGGTTAAGGCTGAAACAGATTTCCAACCAGGTCACTACGAAGGC CGTAACATCTGGTTTGGCGTTCGTGAATTTGCCATGGCTGCAGCCATGAACGGTATTGCCCTTCACGGCGGGACACGCGT TTACGGCGGAACCTTCTTTGTCTTCTCAAACTATCTTCTTCCAGCTGTTCGTATGGCAGCGCTCCAAAACTTGCCAACAG TTTATGTCATGACACATGATTCTATCGCTGTCGGTGAAGATGGGCCAACGCACGAACCAATTGAACAATTGGCAAGTGTT CGCTCAATGCCTAACTTGAACGTTATTCGTCCAGCAGACGGTAACGAAACAAATGCTGCTTGGAAACGTGCCATTGCTGA AACAGATCGCCCAACCATGCTTGTATTGACGCGTCAAAACCTTCCAGTGCTTGAGGGCACAAAAGAATTGGCAGAAGATG GTCTTAGCAAAGGAGCTTATATCTTGTCAGAAGCCAAAGGCGACCTTGATGGTATCTTGATTGCAACAGGTTCAGAAGTG AAACTGGCAATGGATACTCAAGAAGCTCTTGAAGCAGAAGGCATTCATGTGCGTGTCGTATCTATGCCATCACAAAATAT CTTTGACGAACAGTCAGCAGAGTATAAAGAAAGCATCCTACCAGCAGCTGTGACTAAACGTCTCGCTATCGAAGCAGGTT CAAGCTTTGGCTGGGCAAAATATGTCGGCCTATCAGGAAAAACATTGACCATTGACACTTGGGGTGCTTCAGCTCCAGGA AATCGTATCTTCGAAGAATATGGTTTCACTGTGGCAAATGCAACTGAGTTATACAAATCACTCTAA Protein sequence : MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLWNHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLH LAGYDLSVEDLKNFRQWGSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDG DLMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHILVKDGNDLEEIAAAIEAAKAETE KPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFAKKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAAYE AEYPELAAEYQKAFTNEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETDFQPGHYEG RNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQNLPTVYVMTHDSIAVGEDGPTHEPIEQLASV RSMPNLNVIRPADGNETNAAWKRAIAETDRPTMLVLTRQNLPVLEGTKELAEDGLSKGAYILSEAKGDLDGILIATGSEV KLAMDTQEALEAEGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGLSGKTLTIDTWGASAPG NRIFEEYGFTVANATELYKSL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| tktA | AAO17218.1 | TktA | Not tested | tcd island | Protein | 1e-127 | 51 |
| APECO1_2641 | YP_859417.1 | transketolase | Not tested | Not named | Protein | 1e-125 | 49 |
