Gene Information

Name : speA2 (M5005_Spy_0996)
Accession : YP_282359.1
Strain : Streptococcus pyogenes MGAS5005
Genome accession: NC_007297
Putative virulence/resistance : Virulence
Product : enterotoxin
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 984332 - 985087 bp
Length : 756 bp
Strand : +
Note : -

DNA sequence :
ATGGAAAACAATAAAAAAGTATTGAAGAAAATGGTATTTTTTGTTTTAGTGACATTTCTTGGACTAACAATCTCGCAAGA
GGTATTTGCTCAACAAGACCCCGATCCAAGCCAACTTCACAGATCTAGTTTAGTTAAAAACCTTCAAAATATATATTTTC
TTTATGAGGGTGACCCTGTTACTCACGAGAATGTGAAATCTGTTGATCAACTTTTATCTCACGATTTAATATATAATGTT
TCAGGGCCAAATTATGATAAATTAAAAACTGAACTTAAGAACCAAGAGATGGCAACTTTATTTAAGGATAAAAACGTTGA
TATTTATAGTGTAGAATATTACCATCTCTGTTATTTATGTGAAAATGCAGAAAGGAGTGCATGTATCTACGGAGGGGTAA
CAAATCATGAAGGGAATCATTTAGAAATTCCTAAAAAGATAGTCGTTAAAGTATCAATCGATGGTATCCAAAGCCTATCA
TTTGATATTGAAACAAATAAAAAAATGGTAACTGCTCAAGAATTAGACTATAAAGTTAGAAAATATCTTACAGATAATAA
GCAACTATATACTAATGGACCTTCTAAATATGAAACTGGATATATAAAGTTCATACCTAAGAATAAAGAAAGTTTTTGGT
TTGATTTTTTCCCTGAACCAGAATTTACTCAATCTAAATATCTTATGATATATAAAGATAATGAAACGCTTGACTCAAAC
ACAAGCCAAATTGAAGTCTACCTAACAACCAAGTAA

Protein sequence :
MENNKKVLKKMVFFVLVTFLGLTISQEVFAQQDPDPSQLHRSSLVKNLQNIYFLYEGDPVTHENVKSVDQLLSHDLIYNV
SGPNYDKLKTELKNQEMATLFKDKNVDIYSVEYYHLCYLCENAERSACIYGGVTNHEGNHLEIPKKIVVKVSIDGIQSLS
FDIETNKKMVTAQELDYKVRKYLTDNKQLYTNGPSKYETGYIKFIPKNKESFWFDFFPEPEFTQSKYLMIYKDNETLDSN
TSQIEVYLTTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
seb YP_185778.1 enterotoxin B Virulence vSa1 Protein 4e-47 49
seb AAL04126.1 Seb Virulence SaPI3 Protein 3e-47 49
sec4 NP_645576.1 enterotoxin type C precursor Virulence vSa3 Protein 7e-47 47
sec3 NP_372533.1 enterotoxin typeC3 Virulence vSa4 Protein 6e-47 47
sec3 NP_375118.1 enterotoxin C Virulence vSa4 Protein 6e-47 47
sec-bov AAG29599.1 staphylococcal enterotoxin C-bovine Virulence SaPIbov Protein 1e-46 47
sec-bov YP_415865.1 enterotoxin C-bovine Not tested SaPIbov Protein 1e-46 47
sec-ov YP_005735946.1 staphylococcal enterotoxin C-ovine Virulence SaPI1 Protein 4e-45 46
seg NP_372348.1 extracellular enterotoxin type G Virulence vSa¥â Protein 3e-38 45
seg NP_374931.1 extracellular enterotoxin type G Virulence vSa¥â Protein 3e-38 45
unnamed AAL26674.1 enterotoxin-like protein Virulence SCCcap1 Protein 3e-46 45
SAMSHR1132_16710 YP_005326179.1 enterotoxin Virulence vSa¥â Protein 8e-38 44
SAMSHR1132_16730 YP_005326181.1 enterotoxin Virulence vSa¥â Protein 9e-43 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
speA2 YP_282359.1 enterotoxin VFG0951 Protein 4e-105 99
speA2 YP_282359.1 enterotoxin VFG1802 Protein 2e-47 49
speA2 YP_282359.1 enterotoxin VFG1804 Protein 2e-47 47
speA2 YP_282359.1 enterotoxin VFG1805 Protein 2e-46 47
speA2 YP_282359.1 enterotoxin VFG0954 Protein 4e-38 46