Gene Information

Name : apbA (M28_Spy0640)
Accession : YP_280109.1
Strain : Streptococcus pyogenes MGAS6180
Genome accession: NC_007296
Putative virulence/resistance : Unknown
Product : 2-dehydropantoate 2-reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1893
EC number : 1.1.1.169
Position : 662741 - 663664 bp
Length : 924 bp
Strand : +
Note : ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis

DNA sequence :
ATGTTAGTTTATATTGCTGGCTCAGGAGCCATGGGGTGCCGTTTTGGTTACCAAATTTCAAAAACAAATAACGATGTGAT
TTTGTTAGATAACTGGGAAGATCATATCAATGCCATTAAAGAAAACGGTTTAGTGGTGACAGGGGATGTGGAAGAAACAG
TTAAGCTTCCTATTATGAAACCGACTGAAGCCACTCAAGAAGCCGATTTGATTATCTTGTTTACAAAAGCAATGCAGTTG
CCACAAATGCTTCAAGACATTAAAGGCATTATTGGAAAAGAAACCAAAGTGCTTTGCCTTTTAAATGGTCTTGGACACGA
AGACGTTATTCGTCAGTACATTCCAGAGCACAACATTTTGATGGGGGTCACTGTCTGGACTGCTGGTCTAGAAGGACCAG
GTCGTGCTCATCTTCAAGGAGTTGGTGCTCTTAACTTACAAAGTATGGATCCAAACAATCAAGATGCGGGACATCAAGTA
GCTGACTTGTTAAATAAAGCTAACTTAAATGCGACTTATGATGAGAATGTTGTGCCAAACATCTGGCGAAAAGCTTGCGT
GAATGGTACCATGAATTCGACTTGTGCTCTTTTAGATTGTACGATTGGCGAATTATTTGCCAGTGAAGATGGTCTCAAAA
TGGTAAAAGAAATCATCCATGAGTTTGTTATCGTTGGTCAAGCAGAAGGTGTCGAACTAAACGAAGAAGAAATCACACAA
TATGTAATGGATACATCTGTTAAAGCTGCTCACCATTACCCATCAATGCACCAAGACCTTGTGCAAAATCACCGATTGAC
TGAAATTGATTTTATCAATGGTGCAGTCAATACCAAAGGTGAAAAGCTTGGTATCAATACTCCATACTGCCGTATGATTA
CAGAACTAGTTCACGCTAAAGAAGCAGTGTTGAACATCCAATAA

Protein sequence :
MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEDHINAIKENGLVVTGDVEETVKLPIMKPTEATQEADLIILFTKAMQL
PQMLQDIKGIIGKETKVLCLLNGLGHEDVIRQYIPEHNILMGVTVWTAGLEGPGRAHLQGVGALNLQSMDPNNQDAGHQV
ADLLNKANLNATYDENVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLKMVKEIIHEFVIVGQAEGVELNEEEITQ
YVMDTSVKAAHHYPSMHQDLVQNHRLTEIDFINGAVNTKGEKLGINTPYCRMITELVHAKEAVLNIQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ef0037 AAM75243.1 EF0037 Not tested Not named Protein 3e-72 50
EF0517 NP_814296.1 2-dehydropantoate 2-reductase Not tested Not named Protein 4e-72 50