Gene Information

Name : nadC (M28_Spy0168)
Accession : YP_279637.1
Strain : Streptococcus pyogenes MGAS6180
Genome accession: NC_007296
Putative virulence/resistance : Unknown
Product : nicotinate-nucleotide pyrophosphorylase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0157
EC number : 2.4.2.19
Position : 186371 - 187270 bp
Length : 900 bp
Strand : +
Note : catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide

DNA sequence :
GTGATATTAAAAATAGAGGACTTAGTGATGTCAATCATTTCAACTGATTTAACCCCTTTTCAAATAGATGATACATTGAA
AGCAGCCTTGCGAGAAGATGTTCATTCCGAAGATTACAGTACCAATGCCATTTTTGATCATCATGGCCAAGCCAAGGTGT
CGCTTTTTGCCAAGGAAGCTGGTGTTTTAGCGGGGCTAACCGTTTTTCAAAGGGTTTTTACCCTATTTGATGCCGAGGTG
ACCTTCCAGAATCCTCATCAATTTAAGGATGGAGATCGTTTGGCTAGTGGCGATTTGGTTTTAGAAATCATAGGCTCGGT
GAGAAGCCTCTTAACATGTGAACGCGTTGCCTTGAATTTTTTACAACATTTATCAGGGATTGCTTCGATGACAGCTGCTT
ATGTAGAAGCCTTAGGCGATGATCGCATTAAGGTATTTGATACTCGAAAAACCACTCCTAATTTACGTCTTTTTGAGAAA
TATGCCGTGAGAGTTGGCGGTGGCTATAATCATCGCTTTAATTTATCAGATGCTATCATGCTAAAAGACAATCACATTGC
GGCAGTAGGTAGTGTTCAAAAGGCGATTGCTCAAGCGCGTGCCTATGCCCCTTTTGTGAAAATGGTCGAGGTGGAAGTGG
AAAGTCTTGCTGCTGCCGAAGAAGCTGCGGCGGCGGGTGTTGATATTATCATGTTGGATAATATGTCATTGGAACAGATT
GAACAGGCCATTACTCTAATTGCAGGACGTTCTCGGATTGAATGTTCTGGAAATATTGATATGACCACTATTAGCCGTTT
TCGTGGTTTAGCGATTGATTACGTCTCCAGTGGTAGTTTAACCCATAGTGCTAAGAGTCTCGATTTTTCCATGAAGGGTT
TAACCTACCTTGATGTCTAA

Protein sequence :
MILKIEDLVMSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKVSLFAKEAGVLAGLTVFQRVFTLFDAEV
TFQNPHQFKDGDRLASGDLVLEIIGSVRSLLTCERVALNFLQHLSGIASMTAAYVEALGDDRIKVFDTRKTTPNLRLFEK
YAVRVGGGYNHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGVDIIMLDNMSLEQI
EQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAKSLDFSMKGLTYLDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nadC YP_281534.1 nicotinate-nucleotide pyrophosphorylase Not tested Not named Protein 8e-124 99