Gene Information

Name : metB (M28_Spy0144)
Accession : YP_279613.1
Strain : Streptococcus pyogenes MGAS6180
Genome accession: NC_007296
Putative virulence/resistance : Unknown
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.8
Position : 160951 - 162342 bp
Length : 1392 bp
Strand : +
Note : -

DNA sequence :
GTGTTGGCAGCTTGGTCAAAGATGATAAAAGGGCTTGCAAACTTAGCTAAAGGTTGTATAATAAACGTAATCGATCTAAA
AATGATATTGTTGGAAAAATTCATTATCCGTTTAAAAGGTGCCCACTACTTTTCTTATAGGTTAGCAGATCACGCTTTTT
TGAAGAGCTTTTTGGCTTGTGCAACCATTGGGGTGGGACCATTGTCTAAAAGAGAGTTCATTGGAGTCAACGCTATTGCG
GAGGTGCACGAAATGAAAGAAAACACTACTTTATTACATGGCTATACGGTTATTGACGAGTTTACAGGAGCAGCTTCAGT
TCCCATCTATCAGACTTCGACGTTCCACAATTCAGAACTGTATTGTCCTAGTCAAAAACATTTGTACACACGCTTTTCAA
ACCCAACGACTGAAGCTTTAGAAGACGGGTTAGCCTGTTTAGAAAAAGCGACTTATGCGGTGGCTTATGCATCTGGTATG
GCTGCTATTTCAACTGTTTTGATGCTCTTAAAAGCTGGAGATCATGTGATTTTCCCATTGGAGGTCTATGGAGGGACTTG
TCAATTTGCGACAGCTATTTTACCCAATTATCAGATTGAAACAAGCTTTGTAGATATGGCTGATTTAGCAACAGTAAAAG
CAAGTATCAGGCCTAATACGCGTATGATTTATCTAGAGACACCGTCAAATCCGCTCTTGAAAATTTGTGATATTTCAGAG
CTTGTGCAACTCGCCAAAGCTTATGGTGTGCTAACTGTGGCTGATAATACCTTTATGACAAGTTTGTATCAAGAACCCTT
AGCTATGGGTGTGGATATTGTGGTAGAAAGTGTGACCAAATTTATCAATGGTCATAGTGATGTGGTAGCTGGTTTAGCTG
CTACCAATAATGAGGCTATCTACAACCAGCTCAAGCTTTTTCAAAAAAACTTTGGAGCAATTGTTGGGGTCGAAGACGCT
TGGCTGATTCTTCGTGGCATGAAAACTATGGGGATCCGTATGGAACAAGCGGTAAAAAATGCTCAGCAGCTCGCTAACTA
TTTAGCGAAGCACCCCAAAGTTCTTAAGGTACATTACCCTGGCTTAGACAGTCATCCTAATCACGATACCCACCTGCAAC
AAGCTAAGAATGGTGGTGCTGTTTTATCCTTTGAGTTGGCTTCTAAGGAGGAGCTGATGACCTTTACCCATCGTATTCAG
TTGCCGATTTTAGCCGTTAGTCTAGGTGGAGTAGAATCCATTTTGTCACATCCAGCAACGATGTCTCATGCTTGTTTATC
ATCACAAGCGCGGTTGGAACAAGGGGTTGTTGATGGTTTGCTGCGCTTGTCTTGTGGTGTTGAAAATATCGAAGATTTAT
TGGCCGATTTTGAGCAAGCACTTGCTTTTTAA

Protein sequence :
MLAAWSKMIKGLANLAKGCIINVIDLKMILLEKFIIRLKGAHYFSYRLADHAFLKSFLACATIGVGPLSKREFIGVNAIA
EVHEMKENTTLLHGYTVIDEFTGAASVPIYQTSTFHNSELYCPSQKHLYTRFSNPTTEALEDGLACLEKATYAVAYASGM
AAISTVLMLLKAGDHVIFPLEVYGGTCQFATAILPNYQIETSFVDMADLATVKASIRPNTRMIYLETPSNPLLKICDISE
LVQLAKAYGVLTVADNTFMTSLYQEPLAMGVDIVVESVTKFINGHSDVVAGLAATNNEAIYNQLKLFQKNFGAIVGVEDA
WLILRGMKTMGIRMEQAVKNAQQLANYLAKHPKVLKVHYPGLDSHPNHDTHLQQAKNGGAVLSFELASKEELMTFTHRIQ
LPILAVSLGGVESILSHPATMSHACLSSQARLEQGVVDGLLRLSCGVENIEDLLADFEQALAF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 0.0 99
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-77 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-77 43