Gene Information

Name : slo (M28_Spy0139)
Accession : YP_279608.1
Strain : Streptococcus pyogenes MGAS6180
Genome accession: NC_007296
Putative virulence/resistance : Virulence
Product : streptolysin O
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 156783 - 158507 bp
Length : 1725 bp
Strand : +
Note : -

DNA sequence :
ATGAAGGACATGTCTAATAAAAAAACATTTAAAAAATACAGTCGCGTCGCTGGGCTACTAACGGCAGCTCTTATCATTGG
TAATCTTGTTACTGCTAATGCTGAATCGAACAAACAAAACACTGCTAGTACAGAAACCACAACGACAAATGAGCAACCAA
AACCAGAAAGTAGTGAGCTAACTATCGAAAAAGCAGGTCAGAAAATGGATGATATGCTTAACTCTAACGATATGATTAAG
CTTGCTCCCAAAGAAATGCCACTAGAATCTGCAGAAAAAGAAGAAAAAAAGTCAGAAGACAAAAAAAAGAGCGAAGAAGA
TCACACTGAAGAAATCAATGACAAGATTTATTCACTAAATTATAATGAGCTTGAAGTACTTGCTAAAAATGGTGAAACCA
TTGAAAATTTTGTTCCTAAAGAAGGCGTTAAGAAAGCTGATAAATTTATTGTCATTGAAAGAAAGAAAAAAAATATCAAC
ACTACACCAGTCGATATTTCCATTATTGACTCTGTCACTGATATGACCTATCCAGCAGCCCTTCAGCTGGCTGATAAAGG
TTTTACCGAAAACAAACCAGACGCGGTGGTCACCAAGCGAAACCCACAAAAAATCCATATTGATTTACCAGGTATGGGAG
ACAAAGCAACGGTTGAGGTCAATGACCCTACCTATGCCAATGTTTCAACAGCTATTGATAATCTTGTTAACCAATGGCAT
GATAATTATTCTGGTGGTAATACGCTTCCTGCCAGAACACAATATACTGAATCAATGGTATATTCTAAGTCACAGATTGA
AGCAGCTCTAAATGTTAATAGCAAAATCTTAGATGGTACTTTAGGCATTGATTTCAAGTCGATTTCAAAAGGTGAAAAGA
AGGTGATGATTGCAGCATACAAGCAAATCTTTTACACCGTATCAGCAAACCTTCCTAATAATCCTGCGGATGTGTTTGAT
AAATCAGTGACCTTTAAAGAGTTGCAACGAAAAGGTGTCAGCAATGAAGCTCCGCCACTCTTTGTGAGTAACGTAGCCTA
TGGTCGAACTGTTTTTGTCAAACTAGAAACAAGTTCTAAAAGTAATGATGTTGAAGCGGCCTTTAGTGCAGCTCTAAAAG
GAACAGATGTTAAAACGAATGGAAAATACTCTGATATCTTAGAAAATAGTTCATTTACAGCTGTCGTTTTAGGAGGAGAT
GCTGCAGAGCACAATAAGGTGGTCACAAAAGACTTTGATGTTATTAGAAACGTTATCAAAGACAATGCTACCTTCAGTAG
AAAAAACCCAGCTTATCCTATTTCATACACCAGTGTTTTCCTTAAAAATAATAAAATTGCGGGTGTCAATAACAGAACTG
AATACGTTGAAACAACATCTACCGAGTACACTAGTGGAAAAATTAACCTGTCTCATCGAGGTGCGTATGTTGCTCAATAT
GAAATCCTTTGGGATGAAATCAATTATGATGACAAAGGAAAAGAAGTGATTACAAAACGACGTTGGGACAACAACTGGTA
TAGTAAGACATCACCATTTAGCACAGTTATCCCACTAGGAGCTAATTCACGAAATATCCGTATCATGGCCAGAGAGTGCA
CCGGCTTAGCTTGGGAATGGTGGCGAAAAGTGATCGACGAAAGAGATGTGAAACTGTCTAAAGAAATCAATGTCAACATC
TCAGGATCAACCCTGAGCCCATATGGTTCGATTACTTATAAGTAG

Protein sequence :
MKDMSNKKTFKKYSRVAGLLTAALIIGNLVTANAESNKQNTASTETTTTNEQPKPESSELTIEKAGQKMDDMLNSNDMIK
LAPKEMPLESAEKEEKKSEDKKKSEEDHTEEINDKIYSLNYNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNIN
TTPVDISIIDSVTDMTYPAALQLADKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVNDPTYANVSTAIDNLVNQWH
DNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDGTLGIDFKSISKGEKKVMIAAYKQIFYTVSANLPNNPADVFD
KSVTFKELQRKGVSNEAPPLFVSNVAYGRTVFVKLETSSKSNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAVVLGGD
AAEHNKVVTKDFDVIRNVIKDNATFSRKNPAYPISYTSVFLKNNKIAGVNNRTEYVETTSTEYTSGKINLSHRGAYVAQY
EILWDEINYDDKGKEVITKRRWDNNWYSKTSPFSTVIPLGANSRNIRIMARECTGLAWEWWRKVIDERDVKLSKEINVNI
SGSTLSPYGSITYK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
slo YP_281505.1 streptolysin O Virulence Not named Protein 0.0 99
hly AAA69525.1 listeriolysin O Virulence LIPI-1 Protein 1e-93 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
slo YP_279608.1 streptolysin O VFG0976 Protein 0.0 99
slo YP_279608.1 streptolysin O VFG2275 Protein 2e-149 67
slo YP_279608.1 streptolysin O VFG1363 Protein 8e-91 43
slo YP_279608.1 streptolysin O VFG0074 Protein 8e-94 42