Gene Information

Name : ulaA (M28_Spy1650)
Accession : YP_281115.1
Strain : Streptococcus pyogenes MGAS6180
Genome accession: NC_007296
Putative virulence/resistance : Virulence
Product : PTS system ascorbate-specific transporter subunit IIC
Function : -
COG functional category : S : Function unknown
COG ID : COG3037
EC number : -
Position : 1648473 - 1649852 bp
Length : 1380 bp
Strand : -
Note : membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr

DNA sequence :
ATGGAAGCATTATTATCATTTATTCGAGATATTTTAAAAGAACCTGCATTTTTAATGGGCTTGATTGCCTTTGCAGGGTT
GGTGGCTTTGAAAACACCTGCTCATAAGGTGTTGACAGGAACCTTGGGGCCGATTTTGGGATACCTTATGCTTGCTGCAG
GGGCGGGTGTTATTGTGACCAATCTGGACCCTCTTGCCAAACTCATTGAGCACGGTTTTAGCATCACTGGCGTAGTGCCA
AATAATGAAGCCGTCACTTCTGTCGCTCAAAAGATTCTGGGTGTGGAAACTATGTCCATCTTGGTGGTTGGGTTATTGCT
TAATTTGGCTTTTGCTCGTTTTACCCGCTTCAAATACATTTTCTTAACAGGACATCACAGCTTCTTTATGGCTTGTCTCT
TGTCCGCCGTGCTTGGAGCTGTTGATTTCAAAGGAAGTCTTTTGATTATCTTAGGTGGGTTCCTCTTGGGAGCTTGGTCA
GCTATTTCGCCAGCCATTGGTCAACAGTATACTCTGAAAGTGACTGACGGAGATGAAATCGCCATGGGACACTTTGGTAG
TTTGGGCTATTACCTTTCTGCCTGGGTTGGTAGCAAGGTTGGCAAAGACAGTAAAGATACCGAGGACCTTCAGATTTCTG
AAAAATGGAGTTTCTTACGCAACACCACCATTTCAACAGGACTTATCATGGTGCTTTTCTACTTGGTGGCAACAGTGGCT
TCTGTTTTGAGGAATACTTCAGTAACAGAAGAATTAGCAGCAGGTCAAAACCCATTTATCTTTGCTATTAAGAGTGGTCT
TACCTTTGCGGTTGGTGTGGCAATTGTCTACGCCGGTGTTCGCATGATTTTGGCTGACTTGATTCCAGCCTTCCAAGGTA
TTGCTAACAAATTAATTCCAAATGCTATTCCAGCCGTGGATTGTGCGGTATTCTTCCCTTATGCGCCAACCGCTGTTATC
ATCGGTTTTGCGTCAAGTTTCGTTGGTGGCTTACTTGGGATGTTGATTTTAGGAGTTGCAGGTGGTGTCCTGATTATCCC
AGGTATGGTGCCTCATTTCTTCTGCGGTGCAACAGCAGGGATTTTTGGAAATTCAACAGGTGGTCGTCGCGGTGCAATGA
TTGGTGCTTTCGCTAATGGCTTATTACTCGCCTTCTTGCCAGCCATGCTTCTACCTGTACTTGGTAAACTTGGTTTTTCA
AACACGACCTTTGGAGATGTGGATTTCGGTGTTTTAGGGATTTTACTGGGCCGCTTAGGAACGTCGATTGGTCAAATCGG
TATTTACTTGGTGGTTGCTGTGCTTGCTATTGTATTGGTGCTTCCAAACTTTCTGTCAAAATCTCAAGAAGCCATCAATA
ATGTTTCAGAAGAAATCTAA

Protein sequence :
MEALLSFIRDILKEPAFLMGLIAFAGLVALKTPAHKVLTGTLGPILGYLMLAAGAGVIVTNLDPLAKLIEHGFSITGVVP
NNEAVTSVAQKILGVETMSILVVGLLLNLAFARFTRFKYIFLTGHHSFFMACLLSAVLGAVDFKGSLLIILGGFLLGAWS
AISPAIGQQYTLKVTDGDEIAMGHFGSLGYYLSAWVGSKVGKDSKDTEDLQISEKWSFLRNTTISTGLIMVLFYLVATVA
SVLRNTSVTEELAAGQNPFIFAIKSGLTFAVGVAIVYAGVRMILADLIPAFQGIANKLIPNAIPAVDCAVFFPYAPTAVI
IGFASSFVGGLLGMLILGVAGGVLIIPGMVPHFFCGATAGIFGNSTGGRRGAMIGAFANGLLLAFLPAMLLPVLGKLGFS
NTTFGDVDFGVLGILLGRLGTSIGQIGIYLVVAVLAIVLVLPNFLSKSQEAINNVSEEI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAC39291.1 hypothetical protein Not tested LPA Protein 4e-75 50
vpeC ADD91725.1 putative PTS system-specific IIC component VpeC Virulence PAI-I AL862 Protein 4e-75 50
ORF8 AAK27335.1 unknown Not tested PAI-I AL862 Protein 4e-75 49