Gene Information

Name : hsdM (M28_Spy1612)
Accession : YP_281077.1
Strain : Streptococcus pyogenes MGAS6180
Genome accession: NC_007296
Putative virulence/resistance : Unknown
Product : type I restriction-modification system methylation subunit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 1616056 - 1617636 bp
Length : 1581 bp
Strand : +
Note : -

DNA sequence :
ATGGCAGAGAAAACAACTTCACTACGGCAAGCACTATGGCATTCGGCCGATCAATTACGTGGCCAAATGGATGCCAATGA
CTATAAAAACTATCTTCTTGGACTCATCTTTTACAAACATTTATCTGATAAATTACTCTTTGCTGTTTGTGATAATTTAG
AAGAACACTTTAATACCTTTACAGATGCTCAAAAAATCTTTGAAAATGCCTATCAAGATGAAGGCCTAAAAGATGACCTC
ATTTCTGTTGTTACTGGTGATTTAGGTTACTTTATCGAACCTACACTGACCTTTGAAAAACTCATCCAAGATGTTTATCA
CAATACTTTCCAATTAGAATCATTAGCTCAAGGTTTTCGCGATATTGAACAAAGTGGTGAAGACTTTGAAAACTTATTTG
AAGATATTGACCTCTACTCTAAAAAATTAGGCTCTACTCCTCAAAAACAAAATCAAACCATTTCTAATGTCATGAAAACA
TTAAATGAAATTGACTTTGAGGCAGTAGATGGGGATACTTTAGGTGATGCTTATGAATACTTGATTGGTGAATTTGCCAG
TGAGTCAGGAAAAAAAGCAGGTGAGTTCTATACCCCACAAGCTGTCTCTCACTTGATGACTCAGATTGTCTTTTTAGGTT
GGGAAGATCAAAAAGGAATGACCCTTTATGACCCTGCTATGGGATCTGGATCACTCCTTTTAAATGCTAAGAAATATAGT
AACCAATCCGATACCGTCTCTTACTATGGTCAAGAAATCAATACTTCTACTTATAACTTGGCTCGTATGAACATGATGCT
TCATGGCGTTGCCATCGAAAACCAACACTTAAGTAACGCTGATACCTTGGATGCAGACTGGCCAACAGATGAACCAACAA
ACTTTGATGGAGTGTTAATGAACCCACCTTATTCTTTGAAATGGTCAGCGACTGCTGGTTTCTTAACAGATCCACGGTTT
TCAAGTTATGGTGTATTAGCACCAAAATCAAAAGCTGACTTTGCCTTTTTACTTCATGGTTTCTATCATTTAAAAAATAC
AGGAACTATGGCGATTGTCTTACCACACGGTGTCCTTTTCCGTGGTGCTGCAGAAGGCAAGATTCGCCAAAAACTACTCG
AACAAGGGGCTATCGATACCATTATCGGACTCCCATCAAATATCTTTTATAATACAAGCATCCCTACGACTATTATCATA
TTAAAGAAGAACAGAACCAACAAAGATGTCTTCTTTATCGATGCTTCAAAAGAGTTTGATAAAGGCAAAAATCAAAACAC
AATGACAGATAGCCATATCAAAAAGATCCTTGATGCTTATAAGAGTCGTGATAATTCTGATAAGTTTTCATATTTAGCCT
CATTTGATGAAATCATTGAAAATGACTATAACTTAAATATCCCACGCTATGTCGATACCTTTGAGGAAGTCCCCGTCAAA
CCACTGCCAGAATTAGCTAAACAGCTCAGTGACATTGATCAAGAAATTGCCAAAACAAATGCCAAACTAGATCAACTCAT
GAAACAACTAGTCGGAACAACCAAAGAAGCACAAGACGAATTGGATACTTTTAGAAACTAA

Protein sequence :
MAEKTTSLRQALWHSADQLRGQMDANDYKNYLLGLIFYKHLSDKLLFAVCDNLEEHFNTFTDAQKIFENAYQDEGLKDDL
ISVVTGDLGYFIEPTLTFEKLIQDVYHNTFQLESLAQGFRDIEQSGEDFENLFEDIDLYSKKLGSTPQKQNQTISNVMKT
LNEIDFEAVDGDTLGDAYEYLIGEFASESGKKAGEFYTPQAVSHLMTQIVFLGWEDQKGMTLYDPAMGSGSLLLNAKKYS
NQSDTVSYYGQEINTSTYNLARMNMMLHGVAIENQHLSNADTLDADWPTDEPTNFDGVLMNPPYSLKWSATAGFLTDPRF
SSYGVLAPKSKADFAFLLHGFYHLKNTGTMAIVLPHGVLFRGAAEGKIRQKLLEQGAIDTIIGLPSNIFYNTSIPTTIII
LKKNRTNKDVFFIDASKEFDKGKNQNTMTDSHIKKILDAYKSRDNSDKFSYLASFDEIIENDYNLNIPRYVDTFEEVPVK
PLPELAKQLSDIDQEIAKTNAKLDQLMKQLVGTTKEAQDELDTFRN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0053 YP_300143.1 type I restriction-modification system methyltransferase subunit Not tested SCC15305cap Protein 6e-112 50
SAMSHR1132_03780 YP_005324900.1 putative type I restriction enzyme modification protein Not tested vSa¥á Protein 2e-109 48
SAMSHR1132_16570 YP_005326167.1 restriction-modification system, M subunit Not tested vSa¥â Protein 3e-109 48
SA1626 NP_374915.1 hypothetical protein Not tested vSa¥â Protein 3e-109 47
hsdM NP_370955.1 type I site-specific deoxyribonuclease LldI chain Not tested vSa¥á Protein 9e-109 47
hsdM NP_373642.1 type I site-specific deoxyribonuclease LldI subunit HsdM Not tested vSa¥á Protein 2e-109 47
SAS0394 YP_042520.1 restriction enzyme modification protein Not tested vSa¥á Protein 4e-109 47
hsdM1 YP_185366.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 1e-109 47
hsdM NP_645209.1 type I site-specific deoxyribonuclease LldI chain hsdM Not tested vSa¥á Protein 3e-109 47
ORF6 BAC22943.1 - Not tested etd PI Protein 3e-109 47
hsdM2 YP_186690.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 1e-109 47
SAR0433 YP_039884.1 type I restriction enzyme modification protein Not tested vSa¥á Protein 3e-109 47
hsdM YP_001331432.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥á Protein 1e-109 47
SAS1732 YP_043848.1 type I restriction enzyme modification protein Not tested vSa¥â Protein 3e-109 47
hsdM YP_493119.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 1e-109 47
hsdM NP_646568.1 hypothetical protein Not tested vSa¥â Protein 3e-109 47
SAV1808 NP_372332.1 type I restriction enzyme EcoR124II M protein Not tested vSa¥â Protein 3e-109 47
SAR1899 YP_041281.1 type I restriction modification system modification protein Not tested vSa¥â Protein 2e-108 47
SAKOR_00415 YP_008490599.1 Type I restriction-modification system methylation subunit Not tested vSa¥á Protein 1e-109 47
SAKOR_01757 YP_008491945.1 Type I restriction-modification system methylation subunit Not tested vSa¥â Protein 1e-109 47
hsdM YP_001332734.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥â Protein 6e-110 47
hsdM YP_494443.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 6e-110 47