Gene Information

Name : nadE (M28_Spy1398)
Accession : YP_280863.1
Strain : Streptococcus pyogenes MGAS6180
Genome accession: NC_007296
Putative virulence/resistance : Unknown
Product : NAD synthetase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0171
EC number : 6.3.1.5
Position : 1395966 - 1396832 bp
Length : 867 bp
Strand : -
Note : catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli

DNA sequence :
TTGATAACATTCGTAAAGATACTCATGGAAAGAGTGAATGACATGACATTACAAGAAGAGATCATTCGACAATTAGGCGT
CAAGGCTAGCATTGATCCACAAGAAGAAATTCGAAAAACCGTTGATTTTTTAAAAGCTTATTTGCGAAAGCACTCATTTT
TAAAAACTTATGTCTTAGGCATTTCTGGAGGTCAGGATTCTACCCTCGCAGGAAAGCTAGCCCAGATGGCCATTGCAGAG
TTACGGGAGGAAACAAGTGATCAAGCTTACCAATTTATAGCTGTTCGCTTGCCTTACGGGGTTCAGGCTGATGAAGCAGA
TGCGCAAAAAGCCTTGGCTTTTATTGCACCAGATCAGACCCTTACCATTAATATCAAGGCAGCTGTGGACGGTCAAGTAG
AGGCTCTACAAGCAGCAGGCGTTGAGATTTCTGATTTTAACAAAGGTAATATTAAAGCACGTCAGCGAATGATAAGTCAA
TATGCCATTGCTGGCCAAATGGCTGGTGCTGTTATTGGAACGGATCATGCGGCAGAAAACATCACTGGTTTCTTTACTAA
ATTTGGTGATGGTGGAGCAGATATTCTTCCCCTCTTTAGGCTTAACAAACGTCAAGGAAAGGCTCTTTTGAAAGTTTTAG
GAGCAGATGCTGCTTTGTATGAAAAAGTTCCAACTGCTGATTTAGAAGATCAAAAACCAGGCTTGGCTGATGAGGTTGCC
CTAGGGGTGACCTATCAAGACATCGACGACTATTTGGAAGGGAAGCTGATTTCCAAAGCAGCTCAAGCAACTATTGAAAA
ATGGTGGCATAAAGGACAACACAAGCGTCACCTGCCAATCACCATTTTTGATGATTTTTGGAAATAA

Protein sequence :
MITFVKILMERVNDMTLQEEIIRQLGVKASIDPQEEIRKTVDFLKAYLRKHSFLKTYVLGISGGQDSTLAGKLAQMAIAE
LREETSDQAYQFIAVRLPYGVQADEADAQKALAFIAPDQTLTINIKAAVDGQVEALQAAGVEISDFNKGNIKARQRMISQ
YAIAGQMAGAVIGTDHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLGADAALYEKVPTADLEDQKPGLADEVA
LGVTYQDIDDYLEGKLISKAAQATIEKWWHKGQHKRHLPITIFDDFWK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nadE YP_001800880.1 NAD synthetase Not tested Not named Protein 2e-62 54