Gene Information

Name : lysS (MS53_0611)
Accession : YP_278729.1
Strain : Mycoplasma synoviae 53
Genome accession: NC_007294
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 717204 - 718685 bp
Length : 1482 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATTAAAATGAGCATTAAATTAACAGAACAAGAACAAATTAGATTATCTAAATTAGATACATATAAAAAATTAAATATCAA
TCCATTTGAAAAAATTGAAAAGAATTTAAACTACGTATATTCAAAAGATTTAAAAGAAAAATATTCTAGCTATTCTAAAG
AAGAGCTAGAAAGCATGGATCTTTATTTTGATTTATATGGAAGAATAACTTCACAAAGAGGACCTTTTATTGTTATAAAA
GACTACTTTGATAAAATCCAACTTTATTTCAATAAAAAAGAACACCTAGATTTAGCAGAGTTAGTTAGCAACTTAGATTT
AGGCGACATTATTCATGCACATGGAAAGCTATCAAAGACTAATACCGGAGAGCTTGTTGTTAAAATAAAAACTTTAAAAC
TTTTAACAAAAGTGCTAAAACCTCTTCCTGATAAATTTCACGGTCTTAGTGACATTGAAGAAATATATCGTCATAGATAT
TTAGATTTAATATCAAATGAACATTCAATGGAAGTATTTAAAAAACGTAGCAAAATAATTTCTTTAATAAGAAAGTATTT
TGATTCAAATATGTATCTTGAAGTTGAAACTCCATTTTTAAGTAACTATATTTCAGGAGCAGCCGCTAAACCTTTTAAAA
CTTTTCATAACGCTTTAAGCCAAGAATTTACTTTAAGAATAGCGACTGAAATTCCTCTTAAAAAACTTTTAATTGGAGGA
ATTGATAGAGTTTATGAAATGGGTAGAATCTTTAGAAACGAAGGAATAGATACAACCCATAATCCAGAATTTACTACTAT
AGAATTCTATGAAGCTTATTCTAATTTAGAAAAAATGATGCAACGCACTGAAGAGCTTTTTAAATTAATCGCCAAAGAAT
TAAATTTAAAAACTCTCCAAAATAAAGGCGAGGAAATAAATCTAGAAGAGCCATTTAAAAGAGTAGATATGATCGATGAA
GTTTCTAAAGCAACTGGAGTTGATTTTAGAAATGTAACACTAGAAAAAGCTCTTGAGCTAGCAAAAGAACACGGTGTAAA
ACTTAAAAAATATTACACCGTAGGACATATCGCTAATGAGCTTTTTGAAAAACTAATTGAAAAAACTTTAGTTCAACCAA
CTTTTGTAATGGGGCATCCTATCGAAATTTCTCCTCTAACATACGAAGCTAGTGATCCTAGATATGTTGAAAGAGCAGAG
CTATTTATCAACGGTAAAGAATATGCAAATATGTATACCGAGCTTAGTAGCCCAATTGAACAGCTTAAAAGATTTGAAGA
TCAATTAAATGAAAAAGCACAAGGTAACGATGAATCTAGTGACATTGATTGAGACTTTATAGAAGCTCTAAAATACGGAA
TGCCTCCAGCAGGAGGATGCGGTATTGGAATTGATCGTCTGGTAATGCTTTTTACTGAAAAAGAATCAATTCGTGACGTT
TTATTTTTCCCTACACTTAAAAACAAAAAAAGTCAAGGCTAA

Protein sequence :
MKMSIKLTEQEQIRLSKLDTYKKLNINPFEKIEKNLNYVYSKDLKEKYSSYSKEELESMDLYFDLYGRITSQRGPFIVIK
DYFDKIQLYFNKKEHLDLAELVSNLDLGDIIHAHGKLSKTNTGELVVKIKTLKLLTKVLKPLPDKFHGLSDIEEIYRHRY
LDLISNEHSMEVFKKRSKIISLIRKYFDSNMYLEVETPFLSNYISGAAAKPFKTFHNALSQEFTLRIATEIPLKKLLIGG
IDRVYEMGRIFRNEGIDTTHNPEFTTIEFYEAYSNLEKMMQRTEELFKLIAKELNLKTLQNKGEEINLEEPFKRVDMIDE
VSKATGVDFRNVTLEKALELAKEHGVKLKKYYTVGHIANELFEKLIEKTLVQPTFVMGHPIEISPLTYEASDPRYVERAE
LFINGKEYANMYTELSSPIEQLKRFEDQLNEKAQGNDESSDIDWDFIEALKYGMPPAGGCGIGIDRLVMLFTEKESIRDV
LFFPTLKNKKSQG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 5e-65 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_278729.1 lysyl-tRNA synthetase VFG1668 Protein 3e-65 42