Gene Information

Name : nrdE (MS53_0401)
Accession : YP_278524.1
Strain : Mycoplasma synoviae 53
Genome accession: NC_007294
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 451869 - 454043 bp
Length : 2175 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
ATGAAAGACAACACTAACCAATTCAAAGCTGCTAACGAATACTTAGCATACAACGCAATGAGCAAACTAAGTGAAGGAAA
AGACTCTCACGATAACGATCAAAAAGCAATAGGCGCTTACATGAGAGTTGAAATTCTTCCAAAAATGATGCAATGAGAAA
ACATTCACCAAAGAATGCAGTATCTTGTAGAAAATCAATACTACGAAGAAGAAGTAGTTAATAACGTAACAAAAGCTCAA
CTCGAAGAGCTATATCAATTAATTGAAAAATATAATCATAGATTTCCATCTTTTATGGGTGTTGTTAAATTTTTCAATTC
ATATTGCCTTAAAAGCTTTGATGGATCAAAATTTTTAGAAAGCTATTCTGAAAGAGCATTAATGAATGCGCTATTTTTAG
GTGGAAAAGATTTTGAAAGTGTTAAAAACATTTTAGTTGAAATTCTTTCAGGAAGATTTCAACCAGCTACTCCTACTTTT
TTAAACGCTGGAAAAAAACAAAGAGGAGAATATGTATCTTGTTATCTTTTAAGAGTTGAAGATAACATGGAATCTATTGC
AAGAGCGGTTACCACTTCGCTACAGCTTTCAAAAAGAGGTGGAGGAGTAGCGCTTAGCCTAACTAACCTTAGAGAATTCG
GTGCTCCTATTAAGCAAATTCAAGGGCAAGCTACCGGAGTTATTCCGGTTATGAAAATTCTAGAAGATAGCTTTTCATAT
GCTAACCAACTTGGTCAAAGACAAGGTGCAGGAGCTGTGTATCTTCACGCTCACCATCCTGACATTATGACTTTTTTAGA
TTCTAAAAGAGAAAATGCTGATGAAAAAATTAGAATTAAATCACTTTCGCTAGGAATTGTGGTTCCTAACATTACTTTTG
AACTCGCTAAAAATAATGAAGATATGGCGCTATTTTCACCATATGATGTTGAAAAGGTTTATGGCGTTCCATTTTCTGAT
ATTAAAGTAACTGAAGAATACTACAACATGCTTAACAATCCTAAAATTAGAAAAACTTTTGTTAAAGCTAGAAAATTCTT
CCAAACAGTAGCAGAGCTTCACTTTGAATCTGGATATCCATACTTACTTTTTGACGATACCGTTAACGATAGAAATCCAA
ATGCTGGAAGAATTGTTATGTCGAATTTATGTTCTGAAATTGTGCAGTCTTCTAGCCTTACTGAATACGATACTGATTTA
ACTGTTAAAAAATTAGGTGAAGATATTTCATGTAATTTAGGATCAATGAATGTTGATAAATTAATGAATGCCGGAAGCGA
TTTTGGTAAGTCAGTGTTTTACGCTATTAAGTCTTTAGATCACGTTTCTAGAGGTTGTGATTTATCTTGCGCGCCTTCAA
TTAACCATGGAAATAGAAACAACAGAGCCCTAGGACTTGGAGCGATGAATTTACATGGATTTTTTGCAGTTAATGAAGTT
TATTATGATTCTCCTGAAGCGCTAGAGTTTACTAATTTATTTTTCTATGCACTGGCGTATCACGCTTATAAAGCTTCTAA
TCTTTTAGCTAAAGAAAGAAATGAAACTTATAAAAACTTTAAATCATCAAAATATGCAACTGGTGAATATTTTGATAAAT
ACACCAAATGCAAAAGTGATTTATATACAGCTAAACTTCCTAAAGTAATTGAATTATTTAAAAAACATAACGTAACACTG
CCAACTCAAATTGACTGAAGTGAATTAGTTGAAAGCATTAAAAAATATGGACTAGCTAACTCTCATGTTTTAGCGGTAGC
TCCTACTGGTTCAATTTCTTATCTTTCATCATGTACTCCTTCGCTTCAACCAGTGGTATCTCCTGTTGAAGTTAGAAAAG
AAGGAAAACTTGGAAGAGTATATTCGCTAGCTTATAAGCTTGATGAAAATAATTACAAATACTATAAAGATGGAGCCTAC
GAGCTTGGGCCTAATCCAATTATTGATATCGTAGCTCAGGCACAAAAACACGTTGACCAAGCAATATCGCTAACCTTATT
TATGAACGATAAAGCTACAACTCGTGATTTAAACAAAGCCTACATTAGAGCTTTTAAAGCCAAATGTTCATCGATATACT
ACGTTAGAATTCGCCAGGAAGTTTTAGAAGATTCAGAACACATCGACTGAGAAAAAGATGGTCAAAGTTTTGAATGTTCA
AGCTGCACCATCTAG

Protein sequence :
MKDNTNQFKAANEYLAYNAMSKLSEGKDSHDNDQKAIGAYMRVEILPKMMQWENIHQRMQYLVENQYYEEEVVNNVTKAQ
LEELYQLIEKYNHRFPSFMGVVKFFNSYCLKSFDGSKFLESYSERALMNALFLGGKDFESVKNILVEILSGRFQPATPTF
LNAGKKQRGEYVSCYLLRVEDNMESIARAVTTSLQLSKRGGGVALSLTNLREFGAPIKQIQGQATGVIPVMKILEDSFSY
ANQLGQRQGAGAVYLHAHHPDIMTFLDSKRENADEKIRIKSLSLGIVVPNITFELAKNNEDMALFSPYDVEKVYGVPFSD
IKVTEEYYNMLNNPKIRKTFVKARKFFQTVAELHFESGYPYLLFDDTVNDRNPNAGRIVMSNLCSEIVQSSSLTEYDTDL
TVKKLGEDISCNLGSMNVDKLMNAGSDFGKSVFYAIKSLDHVSRGCDLSCAPSINHGNRNNRALGLGAMNLHGFFAVNEV
YYDSPEALEFTNLFFYALAYHAYKASNLLAKERNETYKNFKSSKYATGEYFDKYTKCKSDLYTAKLPKVIELFKKHNVTL
PTQIDWSELVESIKKYGLANSHVLAVAPTGSISYLSSCTPSLQPVVSPVEVRKEGKLGRVYSLAYKLDENNYKYYKDGAY
ELGPNPIIDIVAQAQKHVDQAISLTLFMNDKATTRDLNKAYIRAFKAKCSSIYYVRIRQEVLEDSEHIDWEKDGQSFECS
SCTI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 2e-166 56