Gene Information

Name : nrdF (MS53_0399)
Accession : YP_278522.1
Strain : Mycoplasma synoviae 53
Genome accession: NC_007294
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 450378 - 451397 bp
Length : 1020 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGATCAGTAATAACAAATACTACAATCAATCACTAAGTCCGCTTGATTATGTAAAAAATAATCTGCAAGGAGTTATGAG
ATCGGTTAATTGAAATTTTGTAAACGATCCTAAAGACTTAGAAGTTTGAAATAGAGTTACTCAGAATTTTTGACTTCCTG
AAAAAATTCCTGTAAGTAACGATTTAAAGTCATGAAATGAAATGGATAAATCATGACAAGAACTTTTGGTTAGAACCTTC
ACCGGGCTTACCCTACTTGATACCATTCAAGCTACTTTAGGAGATATTGCTCAAATTCCAAACTCACTAACTGACCATGA
ACAAGTAATTTATGCCAACTTTGCTTTTATGGTTGGGGTGCACGCTAGAAGTTATGGAACTATTTTTTCAACACTAAGTA
ATAGCGATGATATTGAAAAGGCTCACGAGTGAGTTATTAATAATGAAAAGCTGCAAGCTAGAGCTAAATTTTTAGTTCCT
TACTATACATCTAAAGATCCGCTAAAATCTAAAATAGCGGCAGCTTTAATGCCAGGGTTTTTACTCTACGGCGGATTTTA
TTTACCATTTTATCTATCCGCTAGAGGTAAGCTTCCAAATACCAGCGATATTATCAGGCTAATTTTAAGAGATAAAGTTC
TACACAATTATTATTCAGGATATAAATACCGTCAAAAGGTTGAAAAGCTTCCTAAAGAAAAGCAAGCCGAATATAAAGAA
TTTACTTTTAAAATCATGTATGAATTAATCGAGCTGGAAAAGGATTTTTTAAGAGAACTATATGATGGTTTTGGTTTAGC
TGATGAAGCAATCGCATTTAGTTTATACAACGCTGGAAAATTTTTACAAAACTGTGGTTATGAATCGCCATTTACCCCAG
AAGAGACAAAAATTTCACCAGAAGTTTTTGCACAACTATCAGCTAGAGCTGATGAAAATCACGACTTTTTCTCAGGTAAT
GGTAGTTCATATGTGATGGGAGTTAGCGAAGAAACTCAAGACGAAGACTGGGAGTTTTAA

Protein sequence :
MISNNKYYNQSLSPLDYVKNNLQGVMRSVNWNFVNDPKDLEVWNRVTQNFWLPEKIPVSNDLKSWNEMDKSWQELLVRTF
TGLTLLDTIQATLGDIAQIPNSLTDHEQVIYANFAFMVGVHARSYGTIFSTLSNSDDIEKAHEWVINNEKLQARAKFLVP
YYTSKDPLKSKIAAALMPGFLLYGGFYLPFYLSARGKLPNTSDIIRLILRDKVLHNYYSGYKYRQKVEKLPKEKQAEYKE
FTFKIMYELIELEKDFLRELYDGFGLADEAIAFSLYNAGKFLQNCGYESPFTPEETKISPEVFAQLSARADENHDFFSGN
GSSYVMGVSEETQDEDWEF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 4e-67 48