Gene Information

Name : thyA (MS53_0398)
Accession : YP_278521.1
Strain : Mycoplasma synoviae 53
Genome accession: NC_007294
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 449201 - 450070 bp
Length : 870 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAGCAGTATTTACATCTTTTAGAGCATATAAAAACTAGTGGAACTTTTAAAAAAGATCGAACCAATATCGGTACTAT
TTCGCTTTTTGGACTTCAAGCTAGATATAATCTAAAAGAAGGCTTTCCGTTGCTAACTACCAAGAAAATGGCCTGAAAGG
CAATTTGCCATGAACTTTTATGATTTTTAAAAGGTGATACCAACATCAAATATTTAGTTGATAACAACGTAAATATTTGA
AATGAATGGCCTTACGAAATTTTTAAAAAATCTAATGACTATCAAGGCGAATCGTTAAAAGAATTTTCACAAAAAATCAA
AGAAGATAGCTCTTTTGCGCAAAAATATGGTGAGCTAGGCCCTGTATATGGAAAACAATGAAGAGATTTTTTTGGAGTTG
ATCAAATTTCGCAAGTAATTAACGACATTAAAAATAATCCAACATCAAGAAGGCTAATTGTTAGCGCTTGAAATGTAGCC
CAAATTGACAAAATGGCCCTGCCTCCTTGTCATGCTTTTTTCCAATTTTACGTTAATGATAATAATGAACTTTCGCTTCA
TTTATACCAAAGAAGCGGTGATATGTTTTTAGGAGTTCCTTTTAACATTGCATCATATTCGCTGCTTCTTTCAATGGTTG
CGCAAGTTACTAATTTAAAGGTAGGCGAATTTATTCACACCATAGGAGATGCGCATATTTATTCTAATCACATTGACCAA
GTAAATACGCAACTAGAGCGCGCTCCTTATAAACTTCCAAAATTAATTCTTAATAAAAATATTAAAAATATCTTCGATTT
TACATTCGAAGATATTGAGCTTGAAAATTATATTTCACATGAAACTATTAAAGCAAAGGTGGCTGTTTAA

Protein sequence :
MKQYLHLLEHIKTSGTFKKDRTNIGTISLFGLQARYNLKEGFPLLTTKKMAWKAICHELLWFLKGDTNIKYLVDNNVNIW
NEWPYEIFKKSNDYQGESLKEFSQKIKEDSSFAQKYGELGPVYGKQWRDFFGVDQISQVINDIKNNPTSRRLIVSAWNVA
QIDKMALPPCHAFFQFYVNDNNELSLHLYQRSGDMFLGVPFNIASYSLLLSMVAQVTNLKVGEFIHTIGDAHIYSNHIDQ
VNTQLERAPYKLPKLILNKNIKNIFDFTFEDIELENYISHETIKAKVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 7e-68 54
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 9e-56 50