Gene Information

Name : pykA (BPEN_465)
Accession : YP_277960.1
Strain : Candidatus Blochmannia pennsylvanicus BPEN
Genome accession: NC_007292
Putative virulence/resistance : Virulence
Product : pyruvate kinase A
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 553587 - 555035 bp
Length : 1449 bp
Strand : +
Note : ortholog to Escherichia coli bnum: b1854; MultiFun: Metabolism 1.1.1.23, 1.3.1, 1.3.5, 1.3.7

DNA sequence :
ATGTCCCAACAATTGAGAAGAACTAAAATTATCGCTACTTTAGGCCCTGCTACAGATAAAGGTAACAATCTTGAAAAAAT
AATTATCTCAGGAGCAAATATCGTACGACTAAATTTTTCTCATGGAAAAACACAAGAACATTTTGTCCGAGCAGAAAAAG
TACGCGAAATCGCTTCCAAACTAAGTACATATATTGCTATTCTTGGTGATTTACAAGGCCCTAAAATCCGTATCTCAACT
TTTCAGGGAAACGAAATACATTTAAAATCTGGAGATAACTTTTTAATTGATACCATGATGACAAACAATAATAAAAGTAA
TCACAAATGCGTAGGTGTTGATTACGAAGAACTCGCACAAGACGTATACCCAGAAGATTTACTTCTATTAGATGATGGGA
GAATTCAATTAAAAGTTATAACAATCCATAATACTAAAATATATACTAAAGTAATTATTGGAGGTACATTATACAACAAT
AAAGGCTTAAACAAATTAGGAGGAGGGCTTTCAGCGAAAGTCTTAACAAACAAGGACAAAATTGATATTATCACCGCGGC
TCAAATTGGAGTTGACTACCTAGCAATATCATTTCCTCGTAGCAGTATAGATTTAAATTGTGCACGAAAATTAATTGCCG
ATGCTGGTAGTCATGCAAAAATTATTTCTAAAATAGAACGCGCAGAAGTAGTTGCATCCGACGAAACAATAGATGACATC
ATTCATGCATCAGACGCAGTTATGGTAGCCCGAGGAGATTTAGGAGTAGAAATTGGAGAACCAGAACTAGTGGGTGTACA
AAAAAAAATAATACAAAGAGCACGCGCTCTTAATCGCGCAGTCATTACTGCAACTCAAATGATGGAATCTATGGTTCATA
ATTCTATGCCTACTCGCGCAGAAGTAATGGACGTAGCCAATGCAGTATTGGATGGTACTGACGCGGTTATGTTATCCGCT
GAAACTGCTACAGGTCAATATCCATCTGAAACTGTAGCAGCTATGGCTAATGTATGTTTGGGTGCCGAAAAAATTTCAAA
CATCAATTTTTTATCAGACATCAATCAAAAAAAAAAAATTGATGATATCGAAGAAGCTATCGCTATATCGGCAATGTACA
CTGCCAATCATCTAGCAGGAGTAAGTGCAATTATCGTTTTGACTGAATTTGAGAGTACTACGTTATTAATGTCTCGTATC
AATTCAAAATTACCTATTTTTGCGCTATCCCAACACAAACACACCTTAAATATAGTTACTCTTTACAAAGGAGTTATTCC
TATTTATTTTAATAGAACAGGGAATAACGTGATAGATGCCAAATATGCTAGTAATTTATTACGTGACAAAGGACTTCTTC
TATCTGGTGAATTAGTAGTTGTGATACAAAATGATATATACAATAAATGTGATGTAATTAATATTAGTCACATTTTACAA
GTAGAATAA

Protein sequence :
MSQQLRRTKIIATLGPATDKGNNLEKIIISGANIVRLNFSHGKTQEHFVRAEKVREIASKLSTYIAILGDLQGPKIRIST
FQGNEIHLKSGDNFLIDTMMTNNNKSNHKCVGVDYEELAQDVYPEDLLLLDDGRIQLKVITIHNTKIYTKVIIGGTLYNN
KGLNKLGGGLSAKVLTNKDKIDIITAAQIGVDYLAISFPRSSIDLNCARKLIADAGSHAKIISKIERAEVVASDETIDDI
IHASDAVMVARGDLGVEIGEPELVGVQKKIIQRARALNRAVITATQMMESMVHNSMPTRAEVMDVANAVLDGTDAVMLSA
ETATGQYPSETVAAMANVCLGAEKISNINFLSDINQKKKIDDIEEAIAISAMYTANHLAGVSAIIVLTEFESTTLLMSRI
NSKLPIFALSQHKHTLNIVTLYKGVIPIYFNRTGNNVIDAKYASNLLRDKGLLLSGELVVVIQNDIYNKCDVINISHILQ
VE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-50 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-50 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-50 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-50 43
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 1e-67 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykA YP_277960.1 pyruvate kinase A VFG0479 Protein 4e-51 43