Gene Information

Name : serS (BPEN_395)
Accession : YP_277894.1
Strain : Candidatus Blochmannia pennsylvanicus BPEN
Genome accession: NC_007292
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 465241 - 466527 bp
Length : 1287 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATTGATCCCAATTTATTGCGCAGTAATCTTGATTTAGTTGCTAAAAAGCTTGCTCGCAGAAAGTTTATACTAAATAT
TAATAAATTTCGTCAGCAAGAGAGTTTGCGGAAAATTTTACAAAAGAAAACTGAAAGTTTACAGACTGAACGTAAAGCTA
AGGCTAAAATTATAGGAGTAGCTAAGTCTCGTGGAGAAAATGTAGAGTTTTTATGTCAAGAAGCATATGTTTTAGGAAAA
AAATTAACTTCTCTTAAACTTGAAAATAAAGAATTAAAAAACAGGATTAAACAATTTGAGTTATCTTTGCCGAATATTCC
AGATGATCAAGTGCCTTATGGATTTAGAGATCAAGATAATTTAGAAATTATGCGTTGGGGTAAGCCGGGTCAATATAATT
TTCCAATACGGGATCATGTAGCGTTGGGCGCATTAACTAATGGTTTAGATTTTTCTAATGCAACAAAATTAACTGGATCA
CGTTTTATCGTAATGAAAGGACAAATAGCGCATTTGCATCGCGCTTTGTCTCAATTTATGATAGATTTGCATGTTAAACG
TCATGGATATGAAGAGTATTATTTACCATATTTAGTAAATCAAGACTCTTTATATGGTGCAGGTCAATTACCAAAATTTT
ATGAAGACTTGTTTCATATTCAACACTTACAATCTGGAACTAATCCATACGCATTAATACCTACCGCTGAAGTACCTTTA
ATAAATTTAGTTCGTGATGTAATTCTTGATGAAGAAGAATTACCTATTAAGATGGTTGCTCATACTCCATGTTTCCGTTA
TGAAGCAGGATCATATGGTCATCATACTCGTGGATTAATTAGGATGCATCAATTTGATAAAGTTGAAATGGTTCAAGTAG
TACATCCAGATAAATCCATGCAGATCTTAGAAGAAATAACTAGTCACGCGGAACAAGTATTGCAACTACTTAAATTACCA
TATAGGAAAATATTATTATGCACAGGAAATATTGGATTTTCTTCTTGCAAAACATATGATTTGGAAGTATGGCTTCCAGC
ATATAATGCTTATTGCGAGGTTTCTTCTTGTTCAAATGTTGGAGATTTTCAGGCGCGTCGTATAAGAGCGCGATATAAAG
GAAGAATGAATAGAAAAGCGAGATTATTGCATACTTTAAATGCTTCCGGAGTAGCAATAGGTCGAGCATTGGCAGCGGTG
CTTGAAAATTATCAATTAGAAGATGGACGTGTGGCGATTCCTTCGGTACTATCTCCTTATATGAGTGATATAACACATAT
TAATTGA

Protein sequence :
MIDPNLLRSNLDLVAKKLARRKFILNINKFRQQESLRKILQKKTESLQTERKAKAKIIGVAKSRGENVEFLCQEAYVLGK
KLTSLKLENKELKNRIKQFELSLPNIPDDQVPYGFRDQDNLEIMRWGKPGQYNFPIRDHVALGALTNGLDFSNATKLTGS
RFIVMKGQIAHLHRALSQFMIDLHVKRHGYEEYYLPYLVNQDSLYGAGQLPKFYEDLFHIQHLQSGTNPYALIPTAEVPL
INLVRDVILDEEELPIKMVAHTPCFRYEAGSYGHHTRGLIRMHQFDKVEMVQVVHPDKSMQILEEITSHAEQVLQLLKLP
YRKILLCTGNIGFSSCKTYDLEVWLPAYNAYCEVSSCSNVGDFQARRIRARYKGRMNRKARLLHTLNASGVAIGRALAAV
LENYQLEDGRVAIPSVLSPYMSDITHIN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 6e-89 47