Gene Information

Name : aldA (SAR11_0756)
Accession : YP_266177.1
Strain : Candidatus Pelagibacter ubique HTCC1062
Genome accession: NC_007205
Putative virulence/resistance : Virulence
Product : acetaldehyde dehydrogenase II
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 735368 - 736918 bp
Length : 1551 bp
Strand : +
Note : -

DNA sequence :
ATGAGCACAGAAACAGTAAAAGGTGGACGATCTCCGTTACTAGATACGTCTCACTTAAATGTCAAATTTCCATTTAAAGA
AAAATATGGAAATTTTATAGGAGGAAAATTCGTTGAACCAAAATCAGGTAAATATTTTGACAACGTAAGTCCAATCAATA
ATGAAGTTATATGTTCCGTTCCAAGGTCAGATGCAAAAGATGTTGAGGCTGCATTAGATGCTGCACATGCTGCTTTTCCT
ACTTGGGGAGTTACATCAATAACTGAAAGATCTAACATGCTACTTAAAATAGCTGATGTTATTGAAAAAAATCTAGAACT
ATTAGCTACTGCTGAATGTTTAGATAATGGAAAACCAATTAGAGAGTGTATGGCAGCTGACTTACCATTAGTTGTTGATC
ATTGGAGATATTTTGCTGGAGTAATCAGGGCAGAAGAAGGTTCGGTTTCAGAGATAAGTAATAGTGAATATTCTTATCAT
ATACCTGAACCACTTGGTGTAGTTGGACAGATTATACCATGGAACTTTCCATTATTAATGGCAACATGGAAACTTGCACC
AGCACTTGCTGCAGGTAACTGTGTAGTTTTAAAACCAGCTGAACAAACACCAGCATCAATCTTACTATTAATGGAACTTA
TTGGAGACTTATTGCCTCCAGGAGTTGTTAATGTTGTAAGTGGTTTTGGTCTTGAAGCAGGTAAACCATTAGCTTCTTCT
AAAAGAATTAGAAAGATTGCTTTTACAGGTGAGACTACAACTGGACGTTTGATCATGCAATATGCATCACAAAACTTAAT
TCCAATAACTTTAGAATTAGGTGGAAAATCTCCAAATGTTTTCTTTGAAGATGTTATGGATCAAGATGATGATTTCTTTG
ATAAATGTCTTGAAGGTTTTGCAATGTTTACTCTTAATCAGGGTGAAGTTTGTACTTGTCCTAGTAGAGTGTTAATCCAA
GAATCTATCTATGATAAGTTCATGGAAAGAGCAGTTGCTAGAACGAAAGCAGTCAAGCAGGACAATCCTCTAAAAATGGA
AACTATGATTGGTGCTCAAGTATCATTAGAACAAATGGAAAAAATAAAATCTTACTTAGATTTAGGTAAGAAAGAAGGTG
CCAAAGTTCTATGTGGTGGTGAAGTTGCTAACTTAAACAGTGGTTTGGAAAAAGGAAATTATATCCAACCTACTATTTTT
GAAGGCAATAACTCTATGAGAGTTTTCCAAGAAGAAATTTTTGGACCAGTTGTATCTGTTACTAAATTTAAAGATGAAGC
TCATGCATTAGAAATAGCTAATGATACTCTTTATGGTTTAGGAGCAGGTGTTTGGACTAGAAATGGGAATATTGCTTATA
GAATGGGAAGAGGAATCCAGGCTGGTAGAGTTTGGACTAACTGTTACCATGCTTATCCAGCTCATGCTGCTTTTGGAGGA
TACAAACAATCTGGAATCGGTAGAGAAACACATAAAATGATGCTTAATCATTATAGACAGGTGAAAAACTTACACGTGTC
TTACAGTGAGAAAAAATTAGGCTTCTTTTAA

Protein sequence :
MSTETVKGGRSPLLDTSHLNVKFPFKEKYGNFIGGKFVEPKSGKYFDNVSPINNEVICSVPRSDAKDVEAALDAAHAAFP
TWGVTSITERSNMLLKIADVIEKNLELLATAECLDNGKPIRECMAADLPLVVDHWRYFAGVIRAEEGSVSEISNSEYSYH
IPEPLGVVGQIIPWNFPLLMATWKLAPALAAGNCVVLKPAEQTPASILLLMELIGDLLPPGVVNVVSGFGLEAGKPLASS
KRIRKIAFTGETTTGRLIMQYASQNLIPITLELGGKSPNVFFEDVMDQDDDFFDKCLEGFAMFTLNQGEVCTCPSRVLIQ
ESIYDKFMERAVARTKAVKQDNPLKMETMIGAQVSLEQMEKIKSYLDLGKKEGAKVLCGGEVANLNSGLEKGNYIQPTIF
EGNNSMRVFQEEIFGPVVSVTKFKDEAHALEIANDTLYGLGAGVWTRNGNIAYRMGRGIQAGRVWTNCYHAYPAHAAFGG
YKQSGIGRETHKMMLNHYRQVKNLHVSYSEKKLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-130 63
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 7e-135 63
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 7e-135 63
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 7e-135 63
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-134 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldA YP_266177.1 acetaldehyde dehydrogenase II VFG0082 Protein 7e-131 63