Gene Information

Name : smpB (SAR11_1061)
Accession : YP_266470.1
Strain : Candidatus Pelagibacter ubique HTCC1062
Genome accession: NC_007205
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 1028146 - 1028616 bp
Length : 471 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGAACAAGAAAGCCAATCCTGGTTTAAAAATTATTTGCTTAAATAGAAAAGCAAGTTTTAATTTTTTTTTTGAAGACTT
AATTGAAGCTGGGATAGTTCTTAAAGGGTCTGAGATTAAATCAATTAGAGATGGAAAAGTTAATATTGCAGACTCTTATG
CTGTAGAGAAAGACGGTGAAATAGTTTTAATTAACTCTCATATCGCTGCATTTAAGCAAGCCAGTTATTCAAATCACAAT
CCAACAGATGAACGAAAATTATTATTAAACAAAAAGGAAATTAACAAATTAATTGGTAAAATGCAGAGGGATGGCTTTAC
ACTTGTTCCAACAAAGATGTATTTTAAAAAAGGAAAAGCTAAAATAGAAATAGCAGTAGCAAAAGGTAAAAAACAATTTG
ATAAAAGAGCTACTAAAAAAAATAGAGACTGGAATCGTGAAAAAGCAAGACATATTAGAAAATCAAGTTAA

Protein sequence :
MNKKANPGLKIICLNRKASFNFFFEDLIEAGIVLKGSEIKSIRDGKVNIADSYAVEKDGEIVLINSHIAAFKQASYSNHN
PTDERKLLLNKKEINKLIGKMQRDGFTLVPTKMYFKKGKAKIEIAVAKGKKQFDKRATKKNRDWNREKARHIRKSS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 8e-20 49
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 4e-20 44
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 8e-18 41