Gene Information

Name : guaA (Psyc_0009)
Accession : YP_263317.1
Strain : Psychrobacter arcticus 273-4
Genome accession: NC_007204
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 11806 - 13416 bp
Length : 1611 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGACACTTTGTTTATGACCACTGTAACTGCCACCCCCGCAATCAAAGAAGATCGCATCTTAATTCTCGATTTTGGCTC
GCAGTACAGCCAGCTTATCGCCCGCCGTGTACGCGATTCAGGCGTATTCTGTGAGATGTTCCCTTACGATATCGACACCC
AGCGCATCACTGATTTTGGCGCAAAAGGCATCATCTTATCTGGCGGTCCTGAGAGCGTTCACGCGGAAAACAGCCCACGC
ATTAACGATGCCGTATTTGAGCTAGGCGTACCCGTACTTGGTATCTGCTACGGTATGCAAGCAATGGCAGAGCGCTTCGG
TGGTAAAGTTCACGCCAGTGATATCCATGAATTTGGCGCAGCGACCATTAATATCGATGGTAAATCGACGCTGACTAATG
GCATCGAAGACGCAGCAGCGAAGCTCAATGTCTGGATGAGTCATGGTGATAAAGTGGTCGACGCCCCACAAGGCTTCGAT
ATCGTTGCCAGTACGCCAAGCTGCCCGATTGCTATCATGGCTGACGATTCGCGCCACTATTATGGTCTTCAGTTCCACCC
AGAAGTCACTCATACCGCCCAAGGTCAGGCATTGCTAGGACGTTTTGTCCATGAAATCTGTGACTGTGCGGGTAGCTGGA
CGCCCGATAACATCATCGATATGCGTATTGAACAGCTGAAAAAGCAAATCGGTGATAAGCAAGTATTGCTCGGTCTTTCA
GGTGGTGTTGATAGTTCAGTCGTCGCGGCACTTTTGCATAAAGCCATTGGCGACCAATTAACGTGTGTGTTTGTTGATAC
TGGTCTGTTGCGTCTACACGAAGGCGACCAAGTGATGCAAATTTTCGCAGAAAACATGGGCGTAAAAGTCATTCGTGTTG
ATGCTGAAGAGTTATTCCTAACGGCATTGGCTGGCGAGTCTGACCCTGAAGCCAAGCGCAAAATTATTGGTAAAACCTTT
ATCGACGTCTTTGCCAATAGCGCCCGCGAAATCAGTGAGCAAAGCGATGGTAAAGTCATCGAATTCTTAGCGCAAGGGAC
GATTTATCCAGATGTGATTGAATCAGCGAAGTCGCATCAAGGTAAAGCGCACGTGATTAAGAGCCATCATAATGTTGGTG
GTTTGCCAGATGATTTGGCATTTGAATTGGTTGAGCCGTTACGTGATTTGTTTAAAGATGAAGTGCGTAAATTAGGTATC
ACTCTTGGTTTACCTGCGAAGATGATTAACCGTCATCCGTTCCCAGGACCGGGTTTGGGTGTGCGTATCCTAGGCGAAGT
GACCAAAGAATTCGCTGATATCCTGCGTTCTGCTGATGCTATCTTTATGGAAGAGTTAGAAAAATCAGGCTGGTATGAGA
AGACCGCGCAAGCGTTTGCGGTATTCCAACCAATTAAATCGGTCGGCGTGGTCGGTGATGGTCGTCGTTATGCGTGGGTG
ATTGCGCTACGTGCGGTTGAGACCGTGGACTTTATGACCGCGCGTTTTGCTCATCTACCGTATGATTTGATTGAGACGGT
ATCGAATCGCATTATGAATGAGATCGCTGAAGTATCACGCGTGACTTATGATGTGTCGAGCAAGCCACCGGCTACTATTG
AGTGGGAGTAA

Protein sequence :
MDTLFMTTVTATPAIKEDRILILDFGSQYSQLIARRVRDSGVFCEMFPYDIDTQRITDFGAKGIILSGGPESVHAENSPR
INDAVFELGVPVLGICYGMQAMAERFGGKVHASDIHEFGAATINIDGKSTLTNGIEDAAAKLNVWMSHGDKVVDAPQGFD
IVASTPSCPIAIMADDSRHYYGLQFHPEVTHTAQGQALLGRFVHEICDCAGSWTPDNIIDMRIEQLKKQIGDKQVLLGLS
GGVDSSVVAALLHKAIGDQLTCVFVDTGLLRLHEGDQVMQIFAENMGVKVIRVDAEELFLTALAGESDPEAKRKIIGKTF
IDVFANSAREISEQSDGKVIEFLAQGTIYPDVIESAKSHQGKAHVIKSHHNVGGLPDDLAFELVEPLRDLFKDEVRKLGI
TLGLPAKMINRHPFPGPGLGVRILGEVTKEFADILRSADAIFMEELEKSGWYEKTAQAFAVFQPIKSVGVVGDGRRYAWV
IALRAVETVDFMTARFAHLPYDLIETVSNRIMNEIAEVSRVTYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-133 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-133 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-133 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-117 48