Gene Information

Name : thyA (Psyc_2011)
Accession : YP_265292.1
Strain : Psychrobacter arcticus 273-4
Genome accession: NC_007204
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 2477380 - 2478282 bp
Length : 903 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGACCATGAGCAATTCTATTATTAAAAATGACCCTAGTAAAAATAAGCCGATTAAAAACGAGCAAGCCTATTTAGACCT
GTTACGTCTTGTCCTAAGTGAAGGCACTGAAAAAGGTGACCGCACTGGAACCGGTACGGTCAGTCATTTTGGCGCGCAGC
TACGTTTTGACCTAGCCGATGGTTTTCCTTTATTAACCACCAAAAAAGTCCACTTTAAATCCATCATCTATGAACTATTA
TGGTTTTTAAGTGGTAGTACCCACGTTGATTATCTACAACAAAACGGTGTGCGCATCTGGAACGAATGGGCAACCGCAGA
GCAGACCGCACGCTTTAAGCGTCTTGCTGGCGACTTAGGTCCTATTTATGGTCACCAATGGCGTAATTATGGTGCCACTA
AAGTTGAGGACGGCAGCTATGATAACGATGGCTTCGATCAAATCAGTCAAGTTATCGAGCAAATAAAGACCAATCCCAAT
TCACGACGTTTAATTGTGTCTGGTTGGAATCCCGGTGAAGCAGAGCAAGTTGCTTTGCCACCTTGTCATACGATGTTTCA
GTTTTTTGTCGCGGACAACAAACTGTCGTGCCAACTTTATCAGCGCTCAGCGGATTTATTCCTAGGTGTGCCGTTTAATA
TCGCGAGCTACGCGCTCTTGACCCATATGGTAGCGCAAGTTTGCGACTTAGAAGTCGGTGAATTTATTTGGACCGGTGGC
GATTGCCATATTTATCAAAACCATCGCGAGCAAGTTGAATTACAGCTAACGCGTGAGCTTTATACGCTGCCAACCTTGAC
TCTTAACCCTGATGTGCAAGATATTTTTGCTTTTAACTACGACGATATCAGCGTCAATGGCTATGAGTCACATCCAGCGA
TTAAAGCACAAGTTGCAGTATAG

Protein sequence :
MTMSNSIIKNDPSKNKPIKNEQAYLDLLRLVLSEGTEKGDRTGTGTVSHFGAQLRFDLADGFPLLTTKKVHFKSIIYELL
WFLSGSTHVDYLQQNGVRIWNEWATAEQTARFKRLAGDLGPIYGHQWRNYGATKVEDGSYDNDGFDQISQVIEQIKTNPN
SRRLIVSGWNPGEAEQVALPPCHTMFQFFVADNKLSCQLYQRSADLFLGVPFNIASYALLTHMVAQVCDLEVGEFIWTGG
DCHIYQNHREQVELQLTRELYTLPTLTLNPDVQDIFAFNYDDISVNGYESHPAIKAQVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 5e-79 61
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 2e-52 44