Gene Information

Name : lysS (Psyc_1054)
Accession : YP_264340.1
Strain : Psychrobacter arcticus 273-4
Genome accession: NC_007204
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1250966 - 1252510 bp
Length : 1545 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCAAAGCCCAACAATCAAAATCAGCAAAATAACCAAGAGCAAATCCCAGAAGACGCCAACGAACTGATTGCTCAGCT
TCAAGCCAAGCTGGAGGATATCGTTGCTTCAGGCAAACAACCGTATCCGAATACGTTTAAACGTACGGATTATGCGCAAG
ACTTGCAGACGGCTTTTGAGGGTATCTCAAAACAAGAAATTGCTGATAATGATGCTAAAGGCGAAAAAACACAGGTGAAT
GTCGCCGGTCGCGTCATGCTCAACCGTGGTGCATTTATTGTCATCCAAGACATGACAGGTCGTATCCAATTATATGTGGC
ACGCAAAGAGCTAGATGAAGAGACGTTAGCCGACATCAAATCGCTAGATTTGGGTGATATCGTTGGCGTATCAGGTTACA
TCGGTCGCTCTGGTAAAGGTGATTTGTACGTACATATCGAAGAGATGCAATTATTGACCAAAGCATTACGCCCAATGCCA
AATAAGTTTCATGGTTTAGCAGATGTGGAAGCCCGCTATCGCAACCGTCATCTTGATTTGATGACCAATGAGACGACCCG
TGATACTTTTATGGTACGCAGCCAAGTCATCAGCGGTATTCGCAAATTTATGTTGAATGAGCGTTTTATGGAAGTGGAAA
CGCCTATGATGCATCCCATTCCAGGTGGTGCGGTGGCGCGTCCGTTTGTGACTCATCATAATGCGTTAGACATGCCATTA
TATCTGCGTATTGCTCCTGAGCTTTATCTTAAACGCTTAGTCGTTGGTGGCTTTGAGAAAGTATTTGAGATTAACCGCAG
CTTCCGTAATGAGGGCGTGTCAACCCGTCATAATCCTGAATTTACCATGATTGAGTTTTATCAGGCGTATGCTGATTATC
ATGATTTGATGGATTTGACTGAGCGCTTATTTAACGAATTGGCGACAGATATCTTGGGTACCACTGAGATTACCTATCAA
GAAGAAGATATCAGCCTAAAAGCGCCTTTCGAGCGTCTATCTATGTCTAATGCGATTGCCAAATATGCCGAAAACTTCGA
TATGGCACGTATCAATGATCGTGATTATCTCGCAGAGTACGCATCGACAACGCTTAAGCAGCAGGTAAAAGATGTCTTTG
GTGTGGGTAAATTGCAGACCATTATCTTTGAAGAAACCGCTGAGCATCAATTACGTCAGCCAACATTCATCACTGAATAC
CCTGCTGAAACCTCACCACTAGCACGCCGCAGTGATGACAATCCTGAGATTACTGACCGCTTCGAGCTGTTTGTTGGTGG
TCGTGAATTGGCGAATGGCTTTAGTGAGCTGAATGATCCTGCGGATCAGGCTGAGCGTTTCCTTGGTCAAGTGGCTGAAA
AAGACGCTGGCGATGATGAAGCGATGCACTTTGATGCAGAATATATCGAGGCATTGTCTTATGGCTTACCGCCGACTGCT
GGTGAAGGTATTGGTATTGATCGCTTGGTAATGCTATTGACAGACTCTGCCAGTATTCGTGATGTGATTTTATTCCCACA
TATGCGCCGTAAGCTTGAGGGTTAA

Protein sequence :
MSKPNNQNQQNNQEQIPEDANELIAQLQAKLEDIVASGKQPYPNTFKRTDYAQDLQTAFEGISKQEIADNDAKGEKTQVN
VAGRVMLNRGAFIVIQDMTGRIQLYVARKELDEETLADIKSLDLGDIVGVSGYIGRSGKGDLYVHIEEMQLLTKALRPMP
NKFHGLADVEARYRNRHLDLMTNETTRDTFMVRSQVISGIRKFMLNERFMEVETPMMHPIPGGAVARPFVTHHNALDMPL
YLRIAPELYLKRLVVGGFEKVFEINRSFRNEGVSTRHNPEFTMIEFYQAYADYHDLMDLTERLFNELATDILGTTEITYQ
EEDISLKAPFERLSMSNAIAKYAENFDMARINDRDYLAEYASTTLKQQVKDVFGVGKLQTIIFEETAEHQLRQPTFITEY
PAETSPLARRSDDNPEITDRFELFVGGRELANGFSELNDPADQAERFLGQVAEKDAGDDEAMHFDAEYIEALSYGLPPTA
GEGIGIDRLVMLLTDSASIRDVILFPHMRRKLEG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 1e-127 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_264340.1 lysyl-tRNA synthetase VFG1668 Protein 7e-128 53