Gene Information

Name : serS (SH0008)
Accession : YP_251923.1
Strain : Staphylococcus haemolyticus JCSC1435
Genome accession: NC_007168
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 11331 - 12617 bp
Length : 1287 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGACATTAAACTATTTAGAGAGCAAGCAGACACAGTTAAGAGCAAAATTGAACTACGTGGAGATGATCCTAAAGT
AGTTGACGAAGTATTAGAATTAGATAACGAACGTCGTCAATTAATCGGTAAAACTGAAGAAATGAAAGCACGTCGTAACA
AAGTAAGTGAAGAAATCGCTGAAAAGAAACGTAACAAAGAAAATGCAGACGACGTCATCAAAGAAATGCGTGAACTTGGT
GACGAAATCAAAGAAAACGACGCTAAACTTAACGAAGTGGATAATAAAGTTAGAGATATCTTAATTCGTATCCCTAACCT
AATTGCTGAAGATGTACCACAAGGGGATTCTGATGAAGAAAACGTTGAAGTTAAAAAATGGGGTACACCTCGTGAATTTG
ACTTTGAACCAAAAGCACACTGGGACTTAGTAGAAGAATTAAAAATGGCAGACTTTGAACGTGCTGCAAAAATTTCAGGT
GCGCGTTTCGTATACTTAACTAAAGATGGTGCATTATTAGAACGTGCATTAATGAACTACATGCTTACTAAACATACAAC
GCAACACGGTTATACTGAAATGATGACACCTCAATTAGTTAATGCAGATACAATGTTTGGTACTGGTCAATTACCTAAAT
TTGAAGAAGATTTATTCAAAGTTGAAAAAGAAGGTTTATACACAATTCCAACTGCAGAAGTTCCATTAACAAACTTCTAT
AGAGATGAAATCATCCAACCAGGCGTATTACCAGAAAAATTCACTGCTCAAACAGCTTGTTTTCGTAGTGAAGCAGGATC
AGCTGGTAGAGATACAAGAGGTTTAATCCGTTTACACCAATTCGACAAAGTTGAAATGGTTCGTATCGAAAAACCTGAAG
ATTCTTGGGACGCTTTAGAAGATATGACACAAAATGCTGAAGCAATTCTTGAAGAATTAGGTTTACCATATCGTCGTGTT
ATCTTATGTACTGGCGACATCGGTTTCAGTGCTAGTAAAACATACGACTTAGAAGTATGGTTACCAAGTTATGACAACTA
TAAAGAAATTAGTTCTTGCTCAAACTGTACTGATTTCCAAGCGCGTCGTGCTAACATCCGCTTTAAACGTGATGCCGCTT
CTAAACCAGAATTAGCACATACTTTAAATGGTAGTGGACTTGCTGTAGGTCGTACATTTGCAGCTATCGTTGAAAACTAT
CAAAATGCAGATGGTTCAATAACAATTCCAGAAGCATTAGTACCATTCATGGGTGGTAAAACTGAAATCCGTCCAGTAAA
CGACTAA

Protein sequence :
MLDIKLFREQADTVKSKIELRGDDPKVVDEVLELDNERRQLIGKTEEMKARRNKVSEEIAEKKRNKENADDVIKEMRELG
DEIKENDAKLNEVDNKVRDILIRIPNLIAEDVPQGDSDEENVEVKKWGTPREFDFEPKAHWDLVEELKMADFERAAKISG
ARFVYLTKDGALLERALMNYMLTKHTTQHGYTEMMTPQLVNADTMFGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFY
RDEIIQPGVLPEKFTAQTACFRSEAGSAGRDTRGLIRLHQFDKVEMVRIEKPEDSWDALEDMTQNAEAILEELGLPYRRV
ILCTGDIGFSASKTYDLEVWLPSYDNYKEISSCSNCTDFQARRANIRFKRDAASKPELAHTLNGSGLAVGRTFAAIVENY
QNADGSITIPEALVPFMGGKTEIRPVND

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-120 60