Gene Information

Name : hsdM (SH0064)
Accession : YP_251979.1
Strain : Staphylococcus haemolyticus JCSC1435
Genome accession: NC_007168
Putative virulence/resistance : Unknown
Product : type I restriction-modification system DNA methylase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 72766 - 74280 bp
Length : 1515 bp
Strand : -
Note : -

DNA sequence :
ATGGCAACTATAGGTTTTGAAGAAAAATTATGGCAAGCTGCCGATAAATTGAGAGGAAGCATGGATGCTGCTGAGTATAA
AAATGTAGCATTAGGTTTAATCTTTTTAAAATATGTATCAGATTCTTTTGAAGAAAAATATAAAGAATTGAAGCAAGATC
CTTATGCTGACGAAGAGGATCAAGATGAATATTTAGCAGAAAATATTTTCTGGGTTCCAAAAGAAGCAAGATGGCAATAT
ATCAATGATAATGCTAAGAAACCTGAAATTGGACAATTGATTGATAAAGCAATGATTGCGATTGAAAAAGAAAATGAATC
ATTAAAAGGTGTGTTACCTAAAGAATATGCGCGTCCTGCGTTAGATAAAGAAAAATTAGGCGATATTATTGATTTATTTA
CATTTAAGCTTGGAGATACTGAAAGTCGCAAGCAAGATGTGTTAGGTCGTGTGTATGAGTACTTTATTGCTAAGTTTGCA
AGTGCTGAAGGGAAAAATGCAGGAGAATTCTATACTCCATCATCAATTGTAAAGTTATTAGTTGAGATGATTGAACCTTA
TAAAGGCCGTATCTACGATCCATGTTGTGGTTCAGGAGGAATGTTTGTACAAAGTGAACGTTTTGTTGAAAAACATCAAG
GTCGATTAGACGATATTGCAATTTACGGACAAGAGTCTAATCCTACGACTTGGAAATTAGCTAAAATGAATTTAGCCATT
CGTGGAATTGATAATGATTTAGGAGAACGTAATGCCGATACATTCCATAATGACTTACATAAAGGATTAAAAGCAGACTA
CATATTGGCTAACCCACCTTTTAATGCCAGTGATTGGGGACAAGAACGATTACTTGATGACTACCGTTGGCAATTTGGTG
TTCCTCCAAAAGGTAATGCCAACTATGCGTGGATTGAACATATGATTTCAAAATTAGCACCTAACGGAACAGCAGGATTT
GTATTAGCGAATGGGTCGATGTCTACAAGTGGAAAAGATGAATTAGAAATTCGTAAAAATCTTATTGAACAAGATTTAGT
GGAATGTATTGTTACTTTACCTGGTCAACTCTTTTATTCTACACAAATTCCAGTATGCCTTTGGTTCATTAGCAATAATA
AAGGTCAAAATGGTAAAAAAGAACGTAAAAATGAAATTTTATTTATTGATGCTCGTGAAATTGGTCATATGGTATCTAGA
ACATTAAAAGAATTTTCTGATGAAGATATTCAAAAAGTAGCACAAACGTATCATTCTTGGAGAGGCACAAACGATAAATA
TTATGAAGATATAGCTGGTTTTTGTAAAGTAGTTAACCTTGAAGAAGTTAAAAATAATGAATACATTTTAACACCTGGAC
GATACGTTGGTTTGGCTGACGTTGAAGAAGATGAAGAACCTTTTGAACAAAAAATGAAACGTATTACTTCTGAATTAAGT
GAACAATTTGCGAAATCAAAAGAACTTGAAGACCAAATCCGTAAATCACTGGAGGGGTTAGGTTATGGAGTATAA

Protein sequence :
MATIGFEEKLWQAADKLRGSMDAAEYKNVALGLIFLKYVSDSFEEKYKELKQDPYADEEDQDEYLAENIFWVPKEARWQY
INDNAKKPEIGQLIDKAMIAIEKENESLKGVLPKEYARPALDKEKLGDIIDLFTFKLGDTESRKQDVLGRVYEYFIAKFA
SAEGKNAGEFYTPSSIVKLLVEMIEPYKGRIYDPCCGSGGMFVQSERFVEKHQGRLDDIAIYGQESNPTTWKLAKMNLAI
RGIDNDLGERNADTFHNDLHKGLKADYILANPPFNASDWGQERLLDDYRWQFGVPPKGNANYAWIEHMISKLAPNGTAGF
VLANGSMSTSGKDELEIRKNLIEQDLVECIVTLPGQLFYSTQIPVCLWFISNNKGQNGKKERKNEILFIDAREIGHMVSR
TLKEFSDEDIQKVAQTYHSWRGTNDKYYEDIAGFCKVVNLEEVKNNEYILTPGRYVGLADVEEDEEPFEQKMKRITSELS
EQFAKSKELEDQIRKSLEGLGYGV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 0.0 100
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 0.0 99
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 0.0 96
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 2e-127 50