Gene Information

Name : hsdR (SH0062)
Accession : YP_251977.1
Strain : Staphylococcus haemolyticus JCSC1435
Genome accession: NC_007168
Putative virulence/resistance : Unknown
Product : type I restriction-modification system restriction subunit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : -
Position : 68450 - 71569 bp
Length : 3120 bp
Strand : -
Note : -

DNA sequence :
ATGAACTTTCAATTTAATGAAGATGATTTAGAACAAGTCGTATTAGAATGGTTAGAATCACTAAGCTACGACTATAAAAA
AGGTAATGAGATTAGTATGACAGGTCTAGCGCCAGAACGTAAAAGTGACAAAGATGTTGTCCTTCATGAACGTTTAGAGA
AAGCATTAAGAAAAATCAACTCAGACATCCATCCTCGTTTTATTGAAAAAGCGATACATGAACTAACTTTAGAAAAGTCG
CCCAATCTTTTAGAAAATAATCTTACCTTTCATGAAAATTTGATTAATGGTATTGAAATCGAAGACTATGATGACGAAGG
ACAATCGATAGTAGAAATTGTTAAAATCGTTGATTTTGAACATCCACAAAACAATGATTTTTTAGCAGTCAATCAATTCA
CTGTCGTTAATGGAGACTATACAAAACGTCCCGATATTGTACTCTTTATCAATGGTTTGCCTATCGTTGTCATTGAACTT
AAAAATTCAACCAATGAAACTGTAGGCGTCGAAGACGGTTATCATCAATTAGAAACGTACAAGATGCGTATTCCACAATT
ATTTACATTTAATGAAGTACTTGTTACAAGTGATGGCATTAATACTAAAGCAGGTTCACTAACTGCGAACTATGATCGTT
TTATGACTTGGCGTTCTAAAGATGGAGAAACCGAATCTTCGTCAAGTTTAGCTAGCTTAGACGTACTGATTAATGGGATG
TTAAATCCAAAAACCTTACTTGATTTAATTCGATATTTTGTATTATTCCAAGATGATGGCAAAGGACATATCAGTAAAAT
TTTAGCAGCGTATCATCAATACTATGCCGTTAATAAAGCTGTTGATAGGGCTTTATTAGCTTCATCTGGACAAGGTGATG
GTAAAGGTGGCGTCATTTGGCATACCCAAGGGTCTGGTAAAAGCTTAACGATGGTCTTTTTCTCTGGAAAATTAATTCAA
ATGCTGAATAACCCTACCTTAGTCATCGTAACAGATCGTAATGACTTAGATAACCAACTGTACAGTACGTTTGTTAAATC
AAAAGGACGTTCTGGTAAAGGTTTATTAAGACAAACGCCAAAACAAGCTGAAACACGCAAAGAATTAAAATCATTATTAT
CTGTTGAGTCGGGCGGTATTGTATTTACAACAATGCAAAAATTTGAACCTGAACAAAACGAAACGATCATGGCTGCCCTA
ACTGAACGTAAAAATGTGATTGTTATGGCAGATGAAGCACATCGTACACAATATGGCTTTAACGCAAAATACGATGATAA
AGGTGAAGGCATTAAATATGGTTATGCCAAATATTTAAGGGATGCTTTACCGAATGCAACATTCGTAGGATTTACAGGCA
CACCCGTAGCTTCAACGGATAAAAATACACAAATGGTTTTCGGAAACTATATCGATGTTTATGATATGACACAAGCCGTA
GCTGATGGAAGTACCGTTAAAATTTACTATGAAAGTCGTGTAATTCCATTAAATCTACCTCAAAGTTTAGATTTAGATGA
AGCGTATAATGACATTACTGAAGATCAAGAAGAGGATGTAAAACAGCGTTTAAAATCAAAATGGTCCCGTATTGAAGCTT
TAGCAGGCGCAAAACCTCGTGTAGAAGCCCTAGCCAAAGATATCATCCAACACTTTGAAACACGTCAACAAGCGATGAAA
GGTAAAGGAATGATTGTAACGATGAGTCGTCGAATTGCTGTTGATTTATATGATGAAATCATTCGTCTAAAACCAGAATG
GCATTCAGATGATGATGATAAAGGGGTCATCAAAGTAGTGATGACAGGTTCATCTAGTGACCCAACTTCTTTCCAAAGAC
ATATTGGTCCTAAAAAACGTCGTAGTGTATTAGAAAAACGTATGAAAGATGTGAATGATGAATTACAACTCGTGATTGTT
CGAGATATGTGGCTCACAGGGTTTGATGTTCCTTCTATGCATACCATGTATATTGATAAACCAATGAAAGGGCATAATTT
GATGCAAGCAATTGCTCGAGTTAATCGAGTGTTTAAAGATAAGCCGGGTGGATTAATTGTCGATTATGTGGGTATCGCCG
AAAGCTTAAAAGAAGCTCTTAAAGAATATACAGAATCTGATCAAGCTCAAACGGCAATAGATACAGATAAAGCGGTTGAA
TTGATGTTATTGAAGTATGATGTGATTCAAGATATGTTATATAATCTTGATTATTCTAAATTTAATTCAGAGAAAAAATC
GGAACGTTATTATACAATATCGAATACGATGGATTATGTGATTGGTTTAGGTGAAGATGAACGTCAACGTTTTATTAAAA
CGGTCACAGAGTTAGGTAAAGCCTTTGCGCTTTGTGCGACTGAACCTACAGCCCAAGAACTCAATGATGAAATTGCCTTC
TTTAAAGCGGTTAAAGCAGGACTTGTTAAATTGTTACAACCGCCAAAAGAAGGAAAAACACGTAAAACACCTGCAGAAGT
TGAAGCAGAGATTAATCAACTTGTGTCACAATCTGTTGTGACTGAAGATGTCATTGATGTTTATCAAACGCTAGGTCTTG
AACAACCCGATTTATCAATCCTATCTGATGATTTCTTAAAAGATGTCGAAGGATTGAAACAAAAAAATGTTGCGGTAGAA
TTATTAAATCGATTACTCAAAGGGCAAGTTAAATCATTAATGAAAACGAATGCGACAGTATCTAAGCGCTTCTCTGAGAT
GTTAGGAAATTCGATTAATAAATATAATAGTCGTTCCATTGAAACATCAAAAGTGATTGAAGAACTCATTCAACTTGCCA
AAGATATTAAACAAGAACAACAACGAGGAAATGAATTAGGCCTAAATTCGGATGAGATTGCGTTTTACGATGCTTTAGTT
TCACATGAAACAGCGAAAAAAGCGATGGAAGACAAAAAACTACGTGCGATTGCTCACGAGCTAACTAAAACAGTGAAAGA
AAACATGAGTGTTGATTGGTCTAAACGTGATAGCGCAAAAGCTAAAATGCGTGTAGCTGTTAGACGATTGCTTAAGAAAT
ATGGCTATCCGCCAGATTTACAAAAAATGGCTGTAGAGCAGGTCGTAGAACAAGCAGAACTTATGGCGAGTAATCAATAA

Protein sequence :
MNFQFNEDDLEQVVLEWLESLSYDYKKGNEISMTGLAPERKSDKDVVLHERLEKALRKINSDIHPRFIEKAIHELTLEKS
PNLLENNLTFHENLINGIEIEDYDDEGQSIVEIVKIVDFEHPQNNDFLAVNQFTVVNGDYTKRPDIVLFINGLPIVVIEL
KNSTNETVGVEDGYHQLETYKMRIPQLFTFNEVLVTSDGINTKAGSLTANYDRFMTWRSKDGETESSSSLASLDVLINGM
LNPKTLLDLIRYFVLFQDDGKGHISKILAAYHQYYAVNKAVDRALLASSGQGDGKGGVIWHTQGSGKSLTMVFFSGKLIQ
MLNNPTLVIVTDRNDLDNQLYSTFVKSKGRSGKGLLRQTPKQAETRKELKSLLSVESGGIVFTTMQKFEPEQNETIMAAL
TERKNVIVMADEAHRTQYGFNAKYDDKGEGIKYGYAKYLRDALPNATFVGFTGTPVASTDKNTQMVFGNYIDVYDMTQAV
ADGSTVKIYYESRVIPLNLPQSLDLDEAYNDITEDQEEDVKQRLKSKWSRIEALAGAKPRVEALAKDIIQHFETRQQAMK
GKGMIVTMSRRIAVDLYDEIIRLKPEWHSDDDDKGVIKVVMTGSSSDPTSFQRHIGPKKRRSVLEKRMKDVNDELQLVIV
RDMWLTGFDVPSMHTMYIDKPMKGHNLMQAIARVNRVFKDKPGGLIVDYVGIAESLKEALKEYTESDQAQTAIDTDKAVE
LMLLKYDVIQDMLYNLDYSKFNSEKKSERYYTISNTMDYVIGLGEDERQRFIKTVTELGKAFALCATEPTAQELNDEIAF
FKAVKAGLVKLLQPPKEGKTRKTPAEVEAEINQLVSQSVVTEDVIDVYQTLGLEQPDLSILSDDFLKDVEGLKQKNVAVE
LLNRLLKGQVKSLMKTNATVSKRFSEMLGNSINKYNSRSIETSKVIEELIQLAKDIKQEQQRGNELGLNSDEIAFYDALV
SHETAKKAMEDKKLRAIAHELTKTVKENMSVDWSKRDSAKAKMRVAVRRLLKKYGYPPDLQKMAVEQVVEQAELMASNQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 100
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 98
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 98
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 46