Gene Information

Name : guaA (SH2582)
Accession : YP_254497.1
Strain : Staphylococcus haemolyticus JCSC1435
Genome accession: NC_007168
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2593514 - 2595055 bp
Length : 1542 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGAAATGGCTCAAGAGCAAGAGTTGATTCTTGTCTTAGACTTTGGTAGTCAGTACAATCAATTGATTACGCGTCGTAT
TCGTGAAATGGGTGTATACAGTGAATTACATGATCACGAAATTTCGGTTGATGAAATTAAACGTATGAATCCTAAAGGTA
TTATTCTTTCAGGTGGTCCGAATTCAGTATATGAGGAAGGTTCATTCACTATCGACCCTGAAATTTATAATTTAGGCATT
CCTGTACTAGGTATTTGTTATGGTATGCAGTTGACGACTAAACTTTTAGGCGGAAAAGTTGAGCGCGCTAATGAACGTGA
GTATGGTAAAGCAATTATTAACGCAAAATCAGATGAGTTATTCTTTGGATTACCAGCTGAACAAACTGTATGGATGAGTC
ATTCTGATAAAGTAATTGAAATTCCAGACGGATTTGAAGTGATTGCAGATAGTCCAAGTACAAATTATGCGGCAATTGAA
GATAAGAAACGTCGTATTTACGGTGTCCAATTCCATCCTGAAGTACGTCATACAGAATATGGTAATGATTTATTAAGAAA
CTTCGTACGCCGTGTGTGTGAATGCACAGGCGAATGGACAATGGAAAACTTTATCGATATAGAAGTTGAAAAAATCCGTA
AACGCGTTGGAGATCGCAAAGTATTATGTGCGATGAGCGGGGGCGTAGACTCATCAGTTGTAGCTGTCTTATTACATAAA
GCGATTGGCGATCAATTGACATGTATCTTTGTTGACCATGGTTTGCTTCGTAAAGGCGAAGGTGACATGGTTATGGAACA
ATTCGGTGAAGGTTTCGACATGAATATTATCCGTGTGAATGCACAGGAACGTTTCATGGATAAATTAAAAGGTGTATCTG
ATCCAGAACAAAAACGTAAAATTATTGGTAATGAATTTGTATATGTGTTTGATGATGAAGCGGCAAAATTAACTGACGTT
GATTTCTTAGCACAAGGTACACTTTATACTGACGTCATCGAATCAGGTACTAAAACTGCACAAACTATCAAATCTCACCA
TAACGTAGGTGGATTACCTGAAGATATGGAATTTGAACTTATTGAGCCGATTAACACGTTATTTAAAGATGAAGTGCGTG
CATTAGGTATAGAATTAGGCATTCCTGAACATTTAGTATGGAGACAGCCTTTCCCAGGTCCAGGTTTAGGAATCCGTGTA
TTAGGTGAAATTACTGAAGATAAATTAGAAATCGTACGAGAATCAGATGCGATTTTACGTGAAGTTGTGCGTGAGGAAGG
TCTTGAAAGAGACATTTGGCAATACTTCACAGTACTTCCTGGCATTCAATCTGTAGGTGTTATGGGAGACTATCGTACGT
ATGATCATACTGTAGGTATTCGTGCAGTTACATCTATTGACGGTATGACAAGTGACTTCGCCCGCATTGATTGGGAAGTC
CTACAAAAAATCTCAAGCCGTATCGTAAATGAAGTAGATCACGTTAACCGCGTAGTCTATGACATCACTTCTAAGCCACC
AAGCACTATAGAGTGGGAATAG

Protein sequence :
MEMAQEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISVDEIKRMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGI
PVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFFGLPAEQTVWMSHSDKVIEIPDGFEVIADSPSTNYAAIE
DKKRRIYGVQFHPEVRHTEYGNDLLRNFVRRVCECTGEWTMENFIDIEVEKIRKRVGDRKVLCAMSGGVDSSVVAVLLHK
AIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFDMNIIRVNAQERFMDKLKGVSDPEQKRKIIGNEFVYVFDDEAAKLTDV
DFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRALGIELGIPEHLVWRQPFPGPGLGIRV
LGEITEDKLEIVRESDAILREVVREEGLERDIWQYFTVLPGIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEV
LQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 0.0 95
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 0.0 95
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 0.0 95
guaA NP_938969.1 GMP synthase Not tested Not named Protein 9e-128 50