Gene Information

Name : nrdE (SH2162)
Accession : YP_254077.1
Strain : Staphylococcus haemolyticus JCSC1435
Genome accession: NC_007168
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 2193049 - 2195154 bp
Length : 2106 bp
Strand : -
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
ATGAAAATTATGAACGAGAAAAAGTACAATCATATTGAACTAAATAATGAAGTTACGAAACGTAAAGACAATGGTTTCTT
TAACTTGGAGAAAGATCAAGAAGCATTAGCGGTTTATCTAGAAGAAATCCATGACAAAACAATTTATTTTGACAGTGAGA
TTGAACGTTTACACTATCTAGTAGATAATAATTTTTATTTTAATGTCTTTGACAAATATAGCGAAGAAGATTTAGTTGAA
ATCACTGAATTCGCCAAATCTATCAACTTTGAATTTGCAAGCTATATGTCTGCTAGTAAGTTTTATAAAGATTATGCGCT
AAAAACTAATGATAAATCACAATATCTAGAGGATTATAATCAACATGTCGCAATCGTTGCACTATATTTAGCGGATGGTA
ATAAGCAGCAAGCGAAACAATTTATCTTAGCAATGGTCGAACAACGTTATCAACCTGCAACACCAACTTTCTTGAATGCT
GGTCGCGCACGTCGTGGTGAATTAGTATCATGTTTCTTACTAGAGGTAGATGATAGTTTGAACTCTATCAATTTCATTGA
TTCTACTGCCAAGCAATTAAGTAAAATTGGTGGTGGTGTAGCAATAAATCTTTCTAAATTACGTGCTCGTGGTGAAGCTA
TCAAAGGTATTAAAGGTGTAGCCAAAGGTGTGCTACCAGTTGCCAAAGCATTAGAAGGCGGATTTAGCTATGCTGATCAA
CTAGGCCAACGTCCAGGTGCAGGTGCAGTATATTTGAATATCTTCCATTATGATGTAGAAGAGTTCTTAGACACTAAAAA
GGTAAATGCTGATGAAGACTTACGTTTATCAACAATTTCTACTGGTCTTATAGTGCCATCTAAATTCTTTGATTTAGCAA
AAGAAGGCAAAGATTTCTATATGTTTGCACCACATACGGTTAAACAAGAATATGGTGTAACATTAGATGATATTGATTTA
GAAAAGTACTATGACGACATGGTTGCAAACCCAAATATCGTTAAGAAGAAAAAAGACGCAAGAGAAATGTTGAATATGAT
TGCGCAAACACAATTACAATCAGGTTACCCATACTTAATGTTTAAAGATAATGCTAACAAAGTTCATGCCAATTCAAATA
TTGGTCAAATTAAAATGAGTAATTTATGTACAGAAATCTTCCAATTACAAGAGACATCAGTGATTAATGATTATGGTATT
GAAGACGAAATTAAACGCGACATATCATGTAATTTAGGTTCATTAAACATTGTAAATGTGATGGAAACAGGTAAAATTAA
AGATTCTGTTCACACAGGTATGGATGCATTAACAGTAGTTAGTGATGAAGCAAATATTCAAAATGCACCAGGCGTGAGAA
AAGCTAACAGTGAGTTACACTCTGTCGGTCTTGGCGTAATGAACTTACACGGCTATTTAGCTAAAAATAAAATAGGATAT
GAATCAGAGGAAGCTAAAGACTTTGCAAATACTTTCTTCATGATGATGAACTATTATTCAATAGAACGTTCAATGGAAAT
TGCGAAAGAACGTGGGGAAGTATACCAAGACTTTGAACAATCAGATTATGCTAGTGGTAAATACTTTGAGTTTTATACTT
CTCAAGAATTTGAACCTAAATTTGAGAAAGTGAAACGACTATTTGATCATATTGATATTCCAACTGCTAAAGATTGGAAA
GCATTACAAGAACAAGTTCAACAACATGGTTTATATCATGCATATAGACTTGCAATTGCACCTACACAAAGTATTTCATA
TGTACAAAATGCAACAAGTTCAGTTATGCCAATTGTTGATCAAATTGAACGTCGTACTTATGGTAATGCTGAAACATTTT
ATCCAATGCCATTCTTGTCTCCTGAAACAATGTGGTATTATAAATCAGCATTCAATACTGACCAAATGAAATTAATAGAT
TTAATCGCTACGATTCAAACACACGTGGACCAAGGTATTTCAACAATTTTATATGTGAATTCTGAAATTTCAACACGTGA
ATTATCAAGATTATATGTTTATGCTCACCATAAAGGGCTTAAATCGCTATATTATACTCGTAATAAATTATTGAGTGTAG
AAGAATGTACAAGCTGTGCTATCTAA

Protein sequence :
MKIMNEKKYNHIELNNEVTKRKDNGFFNLEKDQEALAVYLEEIHDKTIYFDSEIERLHYLVDNNFYFNVFDKYSEEDLVE
ITEFAKSINFEFASYMSASKFYKDYALKTNDKSQYLEDYNQHVAIVALYLADGNKQQAKQFILAMVEQRYQPATPTFLNA
GRARRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPVAKALEGGFSYADQ
LGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGLIVPSKFFDLAKEGKDFYMFAPHTVKQEYGVTLDDIDL
EKYYDDMVANPNIVKKKKDAREMLNMIAQTQLQSGYPYLMFKDNANKVHANSNIGQIKMSNLCTEIFQLQETSVINDYGI
EDEIKRDISCNLGSLNIVNVMETGKIKDSVHTGMDALTVVSDEANIQNAPGVRKANSELHSVGLGVMNLHGYLAKNKIGY
ESEEAKDFANTFFMMMNYYSIERSMEIAKERGEVYQDFEQSDYASGKYFEFYTSQEFEPKFEKVKRLFDHIDIPTAKDWK
ALQEQVQQHGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPETMWYYKSAFNTDQMKLID
LIATIQTHVDQGISTILYVNSEISTRELSRLYVYAHHKGLKSLYYTRNKLLSVEECTSCAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 2e-137 44