Gene Information

Name : smpB (SH2104)
Accession : YP_254019.1
Strain : Staphylococcus haemolyticus JCSC1435
Genome accession: NC_007168
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 2134543 - 2135013 bp
Length : 471 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGCTAAGAAGAAAACGAAATCACCCGGTACACTAGCTGAAAACCGTAAAGCCAGACATGATTATAATATTGAAGATAC
AATTGAAGCGGGTATTGCTTTAAAGGGAACAGAGATTAAATCTATTCGTCGAGGTAGTGCCAATTTGAAAGATAGCTATG
CTCAAGTTAAACGTGGCGAGATGTTCATTAATAATATGCACATTGCACCTTATGAGGAAGGTAACCGTTTCAATCATGAC
CCTTTACGTTCTAGAAAGTTATTACTTCATAAGAAGGAAATTATTAAACTTGGGGAACGTACGAGAGAAATTGGCTATTC
ACTTATTCCATTAAAACTTTATTTAAAACATGGTCAATGTAAAGTCTTATTAGGCGTAGCACGTGGTAAGAAAATACATG
ATAAACGTCAAGCTTTAAAAGATAAAGCAATGAAACGTGATGTTGATCGTGCAATCAAAGACCGTTATTAA

Protein sequence :
MAKKKTKSPGTLAENRKARHDYNIEDTIEAGIALKGTEIKSIRRGSANLKDSYAQVKRGEMFINNMHIAPYEEGNRFNHD
PLRSRKLLLHKKEIIKLGERTREIGYSLIPLKLYLKHGQCKVLLGVARGKKIHDKRQALKDKAMKRDVDRAIKDRY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 1e-50 87
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 6e-22 46
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 1e-21 45