Gene Information

Name : thyA (SH1479)
Accession : YP_253394.1
Strain : Staphylococcus haemolyticus JCSC1435
Genome accession: NC_007168
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 1520268 - 1521224 bp
Length : 957 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGTTAAATTCCTTTGATTCAGCTTATCATGCTTTATGCGAAGAAATATTAGAAATTGGTAATCAACGGGATGATCGTAC
TCATACCGGTACTTTTTCTAAATTTGGTCATCAGTTACGATTTGATTTATCTAAGGGTTTCCCATTACTTACAACAAAAA
AAGTATCTTTCAAACTTATCGCTACAGAATTATTATGGTTTATTAAAGGCGATACAAATATACAATACTTACTAAAATAT
AATAATAATATTTGGAATGAGTGGGCCTTCGAGAAATATGTGCAATCTAATGATTATCATGGTCCTGATATGACTAATTT
TGGTCATAGAGCACTACAAGATGATGAATTTAATGAACTGTATAAAGAAGAAATGTCTAAATTCAAACAACACATTTTAA
ATGATGACTCATTTGCAAAAAAATACGGAGATTTAGGTAATGTATATGGTAAACAATGGAGAGATTGGGTAGATAAAGAA
GGTAACCACTTTGATCAACTTAAAACCGTTATTGAACAAATTAAAAATAGTCCAAATTCTCGCCGACATATTGTCTCAGC
ATGGAATCCAACAGAAATAGATAGCATGGCTTTGCCACCATGCCATACTATGTTCCAATTTTATGTTCAAGATGGCAGAT
TAAGTTGTCAATTGTATCAACGAAGTGCAGATATTTTCTTAGGTGTACCATTTAATATTGCTAGCTATGCATTATTAACA
CATTTAATAGCAAAAGAGTGTAATCTTGAAGTTGGAGAATTTGTGCATACTTTTGGTGACGCACATATTTACTCTAATCA
TATTGAAGCAATAAAAACACAATTGTCTAGAAACAGTTTTGATCCGCCAACTTTAAAAATTAATTCAAATGCATCTATTT
TCGATATCAATTACGAAGATTTAGAATTAATTGGATATAACTCACACCCAGCAATTAAGGCACCAATTGCAGTATAA

Protein sequence :
MLNSFDSAYHALCEEILEIGNQRDDRTHTGTFSKFGHQLRFDLSKGFPLLTTKKVSFKLIATELLWFIKGDTNIQYLLKY
NNNIWNEWAFEKYVQSNDYHGPDMTNFGHRALQDDEFNELYKEEMSKFKQHILNDDSFAKKYGDLGNVYGKQWRDWVDKE
GNHFDQLKTVIEQIKNSPNSRRHIVSAWNPTEIDSMALPPCHTMFQFYVQDGRLSCQLYQRSADIFLGVPFNIASYALLT
HLIAKECNLEVGEFVHTFGDAHIYSNHIEAIKTQLSRNSFDPPTLKINSNASIFDINYEDLELIGYNSHPAIKAPIAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 8e-136 86