Gene Information

Name : thiC (jk0855)
Accession : YP_250635.1
Strain : Corynebacterium jeikeium K411
Genome accession: NC_007164
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 1016743 - 1018668 bp
Length : 1926 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGACGGATACGTCTACCCAAAACACCGCCACCCCTACCGACGAGTACGGCGCGGAGATCCACCCGAAGCACAGCTTCTC
CCCCATCGAGAAGACCGTGGAATCCTTCGGCAAGACTTTCACACTGGAGGTGCCGGAGACGGAGATCCAGCTGGACGACT
CCCCGACCGGCCCGAACGAGCCGGTGCGCATCTACCGCACTCGTGGCCCGTGGGCCGAGCCGACCAAGGGGCTGGAGGGC
CTGCGCAGCGAGTGGATCGAAGCCCGCGACGACGTGGAGGCTTACGAAGGCCGCCGCCGCAACCTGCTGGACGACGGCAA
CCGCGCTGTCAAGCGCGGCGAGGCCAGCGAGGAGTGGAAGGGTTCCACCCGCCCGACTCTGCGCGCCAAGGAAGGCAAGC
GCGTCACCCAGATGCACTATGCCCGCCAGGGCATCATCACCCCGGAGATGGAGTACGTAGCACTGCGCGAGCACTGCGAC
GTGGAGAAGGTTCGCGAGCAGGTAGCCTCCGGCAAGGCCATCATCCCGAACAACATCAACCACCCGGAGTCCGAGCCGAT
GATCATCGGCAACGCCTTCACCACGAAGATCAACGCCAACATCGGTAACTCCGCCGTCACTTCCTCCATCCGCGAAGAGG
TGGACAAGCTGCGCTGGGCTACCCGCTGGGGCGCGGACACCGTGATGGATCTGTCCACCGGTAACGACATTCACACCACC
CGCGAGTGGATCCTGCGCAACTCCCCGGTGCCAATCGGCACTGTGCCGATCTACCAGGCTCTGGAGAAGGTCGATGGTGT
GGCCGAGGACCTGACCTGGGAGATCTTCCGCGATACCGTTATTGAGCAGTGCGAGCAGGGTGTGGATTACATGACCATCC
ACGCCGGCGTGCGCCTGCCTTTCGTGCCGCTGACCACCAAGCGCGTCACCGGCATCGTCTCCCGCGGCGGCTCCATCATG
GCCGGCTGGTGCCTGGCGCACCACAAGGAATCCTTCCTGTACGAGAACTTCGACGAGCTGTGCGAGATCTTCGCCAAGTA
CGACGTCGCGTTCTCCCTGGGCGACGGCCTGCGCCCGGGCTCCATCGCGGACGCCAACGACGCAGCCCAGTTCGCAGAGC
TGAAGACCATCGGCGAGCTGACCCACCGCGCCTGGGAGTACGACGTGCAGGTCATGGTGGAAGGTCCCGGCCACGTGCCG
CTGAACATGGTGCAGGTCAACAACGAAAAGGAGCAGGAATGGTGCGGCGGCGCGCCGTTCTACACGCTGGGGCCGCTGGT
CACGGACATCGCTCCGGGCTACGACCACATCACCTCCGCCATTGGTGCGGCAAATATCGCCATGGGTGGCACCGCAATGC
TGTGCTACGTCACCCCAAAGGAGCACCTTGGCCTGCCGAACAAGGACGACGTGAAGACCGGCGTGATCACCTACAAGGTC
TCCGCCCACGCCGCCGATGTTGCCAAGGGCCACCCGGGTGCCCACGAGTGGGACGACGCCATGAGTAAGGCTCGCTTCGA
GTTCCGCTGGCACGACCAGTTCGCCCTCTCCCTGGACCCGGACACGGCGCAGGCGTACCACGACGAAACACTGCCCGCGG
AGCCGGCGAAGACAGCGCACTTCTGCTCCATGTGCGGCCCGAAGTTCTGCTCCATGCGCATCAGTCAGGACATCCGTGAT
GCCTTCGGCGACGAGATCGACGAGGCGCTGGCCACCGACCAGAAGCAGTCGCTGGTCAAGGACCTGGGCCTGCCGGGCTT
CGGCCGCCAGAGCGTAGACGGCATCGACAGCCTAAGCGCCGCGGGCGAGGAGGAGATGGCGGAGGAGTTCCGCCGCGCGG
GCTCCCAGCTGTACTTGAACCGCGACGAGGCGAAGGAAGTCGCCGAGGATCTGCAGAAGGAGGCGGCAGCGCACGGTGAG
CGCTAG

Protein sequence :
MTDTSTQNTATPTDEYGAEIHPKHSFSPIEKTVESFGKTFTLEVPETEIQLDDSPTGPNEPVRIYRTRGPWAEPTKGLEG
LRSEWIEARDDVEAYEGRRRNLLDDGNRAVKRGEASEEWKGSTRPTLRAKEGKRVTQMHYARQGIITPEMEYVALREHCD
VEKVREQVASGKAIIPNNINHPESEPMIIGNAFTTKINANIGNSAVTSSIREEVDKLRWATRWGADTVMDLSTGNDIHTT
REWILRNSPVPIGTVPIYQALEKVDGVAEDLTWEIFRDTVIEQCEQGVDYMTIHAGVRLPFVPLTTKRVTGIVSRGGSIM
AGWCLAHHKESFLYENFDELCEIFAKYDVAFSLGDGLRPGSIADANDAAQFAELKTIGELTHRAWEYDVQVMVEGPGHVP
LNMVQVNNEKEQEWCGGAPFYTLGPLVTDIAPGYDHITSAIGAANIAMGGTAMLCYVTPKEHLGLPNKDDVKTGVITYKV
SAHAADVAKGHPGAHEWDDAMSKARFEFRWHDQFALSLDPDTAQAYHDETLPAEPAKTAHFCSMCGPKFCSMRISQDIRD
AFGDEIDEALATDQKQSLVKDLGLPGFGRQSVDGIDSLSAAGEEEMAEEFRRAGSQLYLNRDEAKEVAEDLQKEAAAHGE
R

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 2e-171 64
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 2e-171 64
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 5e-160 62