Gene Information

Name : pyk (jk0801)
Accession : YP_250581.1
Strain : Corynebacterium jeikeium K411
Genome accession: NC_007164
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 954167 - 955585 bp
Length : 1419 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
GTGAATAGAAGAACCAAGATTGTTTGCACCCTGGGTCCCGCGGTCGCTTCGAAGGAGCAGATTCGCGGGCTCGTAGACGC
AGGAATGAACGTTGCGCGCCTCAACTTTTCCCACGGCGAGCACGCAGACCACGAGCAGAATTACAACTGGGTTCGACAGG
CCACCGATGAATCCGGCAAGGCCGTCGGTATCCTCGCCGACCTGCAAGGCCCGAAGATCCGCCTCGGACGCTTCGCAGAG
GGCGCAACCGTCTGGGCGACCGGCGAGACCGTACGCATCACCGTCGACGACGTACAGGGCACACACGACCGCGTGTCCAC
CACCTACAAGGGCTTGGCCCGCGACGCCCGCCCCGGCGACCGCCTGCTGGTCGACGACGGCAAGATCGCGCTGGTGTGCA
AGGAAGTCGACGGCAACGACGTCGTGTGCGAGGTCATCGAGGGAGGCCCGGTTTCCAACAACAAGGGTGTCTCCCTGCCG
GGCATGAACATCTCCGTGCCGGCACTGAGCGAGAAGGACACCGAAGACCTGCGCTTCGCCCTGCAGCTGGGCGTGGACTT
CATCGCCCTGTCCTTCGTGCGCAGCCCCTCCGACGTGGAACTGGTGCGCGACATCATGGACGAGGTTGGCCGCCGCGTGC
CGGTGATCGCCAAGCTGGAGAAGCCGGAGGCAGTCGACGCGCTGGAGCCGGTCATCCTAGCCTTCGATGCCATCATGGTC
GCCCGCGGTGACCTGGGCGTGGAAGTGCCGCTGGAAGACGTGCCGCTGGTGCAGAAGCGCGCCATCCAGATCGCCCGCGA
GAACGCCAAGCCGGTGATCGTGGCGACGCAGATGCTGGACTCCATGATCGAGAACTCCCGCCCGACGCGCGCCGAAGCCT
CCGACGTGGCCAACGCCGTGCTCGACGGTGCGGATGCCGTGATGCTCTCCGGCGAGACCTCCATCGGCAAGCACCCGATC
ACCACCGTGGAGACGATGGCTCGCATCGTGCGCGCCGCCGAGATTGACGGGGAAGTGCCGCCGCTGACGCACCGCCCGCG
CACCCGCCGCGGCGTGATTTCCTACGCGGCAAAGGACATCGGCGAGCGCCTGAATGCGAAGGCACTGGTGGCCTTCACCT
CCTCCGGCGATACCGCCAAGCGCGTGGCGCGCCTACGCTCCCACCTGCCGCTGCTGGTGTTCACGCCGTCGCAGGCCGTG
CGCTCGCAGCTGGCGCTGACGTGGGGCGTGGAGACGTTCCTCATCGAAGACGTGAAGTCCACCGACGAGATGATGGACAC
CGTCGACCACCACCTGCTGGCTATGCCGCAATACAAGTACGACGACATGATGGTCGTCGTCGCCGGCTCCCCGCCCGGGA
TCTCCGGCAACACCAACATGATCCAGGTGCACCTGCTGGGTCAGGAGCGGAAGAGGTAA

Protein sequence :
MNRRTKIVCTLGPAVASKEQIRGLVDAGMNVARLNFSHGEHADHEQNYNWVRQATDESGKAVGILADLQGPKIRLGRFAE
GATVWATGETVRITVDDVQGTHDRVSTTYKGLARDARPGDRLLVDDGKIALVCKEVDGNDVVCEVIEGGPVSNNKGVSLP
GMNISVPALSEKDTEDLRFALQLGVDFIALSFVRSPSDVELVRDIMDEVGRRVPVIAKLEKPEAVDALEPVILAFDAIMV
ARGDLGVEVPLEDVPLVQKRAIQIARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADAVMLSGETSIGKHPI
TTVETMARIVRAAEIDGEVPPLTHRPRTRRGVISYAAKDIGERLNAKALVAFTSSGDTAKRVARLRSHLPLLVFTPSQAV
RSQLALTWGVETFLIEDVKSTDEMMDTVDHHLLAMPQYKYDDMMVVVAGSPPGISGNTNMIQVHLLGQERKR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 7e-75 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-75 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-75 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-74 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_250581.1 pyruvate kinase VFG0479 Protein 3e-75 43