Gene Information

Name : nrdE (jk0478)
Accession : YP_250253.1
Strain : Corynebacterium jeikeium K411
Genome accession: NC_007164
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 581056 - 583218 bp
Length : 2163 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
ATGACTGGCACCGAGCTTGGCAAGACCGTCCAGGAGCCCGTTGACCAGCGGGAGCAGCTGGATTATCACGCTCTGAACGC
GATGTTGAACCTGTACAACGATGCAGGGGAGATCCAGTTCGACAAGGATCGCGAGGCTGCAAACCAGTACTTCCTGCAGC
ATGTCAACCAGAACACCGTTTACTTCCACGATCTGGAAGAAAAGGTTAAGTACCTGGTGGACAACGAGTACTACGACCCC
GAGGTGCTGGATCAGTACGAGTTCAGCTTTGTGAAGTCCCTGTTTAAGCAGGCCTACGCGAAGAAGTTCCGCTTCCAGTC
GTTCCTGGGTGCGTACAAGTACTACACCTCCTACACACTGAAGACCTTCGACGGTCGCCGTTACCTGGAGCGTTTCGAGG
ACCGCGTGTGCATGGTTGCATTGGGGCTGGCGGCGGGGGATACCGAGTTGGCGTCCAACCTGGTCGACGAGATCATGGAC
GGCCGCTTCCAGCCTGCAACGCCAACCTTCCTCAACATCGGCAAGAAGCAGCGCGGTGAGCCGGTTTCGTGCTTCCTGCT
GCGCATCGAGGACAACATGGAGTCCATCGGCCGTTCCATCAACTCCGCGCTGCAGCTGTCCAAGCGCGGCGGCGGTGTGG
CTCTGCTGCTGTCGAACGTGCGTGAAGCCGGCGCGCCGATTAAGCACATCGAGAACCAGTCCTCCGGCGTGATCCCCGTG
ATGAAGCTGCTGGAAGATGCCTTCAGCTACGCCAACCAGCTGGGCGCCCGCCAGGGTGCCGGTGCGGTCTACCTGAGCGC
GCACCACCCGGACATCCTGCGCTTCCTGGATACCAAGCGTGAGAACGCGGACGAAAAGATTCGCATTAAGACCCTCTCGC
TGGGCGTGGTGATCCCGGACATTACCTTCGAGCTAGCCAAGCGCAACGACGACATGTACCTGTTCAGCCCGTACGACGTC
GAGCGCGTGTACGGCAAGCCGTTCGCCGACGTCTCCATCACCGAACACTACGAGGAGATGGTGGAGGATCCGCGAATCCG
CAAGTCCAAGATCAACGCGCGTGCGTTCTTCCAGACCCTGGCGGAGATCCAGTTCGAGTCCGGATACCCGTACATCATGT
TCGAGGACACGGTTAATAAGGCCAACCCGATCGAGGGCCGCATTACCCACTCGAACCTATGCTCCGAGATTCTGCAGGTC
TCCACCCCGTCGGAGTTCAATGCTGACCTGTCGTACAAGCAGATCGGCGACGATATTTCTTGCAACCTGGGCTCGATGAA
TATTGCGAAGGCGATGGATTCGGAGGACTTCTCCAAGACCATCGAGACCGCCATCCGTGGCCTGACCGCCGTGGCGGACC
AGACCTCCATTGACTCCGTGCCTTCGGTGCGCCAGGGTAACGACAACTCCCACGCCATCGGCCTGGGCCAGATGAACCTG
CACGGATTCCTGGGGCGTGAGCACATCCACTACGGTTCCGAAGAGGCGCTGGACTTCACCAACGCCTACTTTGCGACCGT
GATGTATGAGGCGTTGAAGGCTTCCAACAAGATCGCCCAGGAGCGCGGGGAGAAGTTCCACAACTTCGAAAACTCCCAGT
ACGCCACCGGAGAGTTCTTCGACCGCTACGATCCGGCCGAGTTCGCCCCCAAGACGGAGCGTATCCGCCAAATCATCGGC
AACTCCAGCATCCAGGTGCCAACCGCGCAGGACTGGCAACAGCTGAAGGACGATGTGCAGGCTCACGGTCTATACAACCG
CAACCTGCAGGCTATTCCGCCGACGGGTTCCATCTCCTACATCAACAACTCCACGTCCTCGATTCACCCGATCGCCTCCA
AGATCGAAATTCGTAAGGAGGGCAAGATCGGTCGTGTGTACTACCCGGCTCCGTACATGACGAACGACAACCTGGAGTAC
TACGAGGACGCGTACGAGATCGGCTACGAAAAGATCATCGACACTTACGCAGTCGCGACGAAGTACGTGGATCAGGGCCT
ATCGCTGACCCTGTTCTTCAAGGACACCGCCACCACGCGCGACATCAACCGTGCGCAGATCTATGCGTGGCGCAAGGGGA
TCAAGACGATCTACTACATCCGCCTCCGCCAGACGGCCTTGACCGGCACCGAGGTTGAGGGCTGCGTGAGCTGCATGCTC
TAA

Protein sequence :
MTGTELGKTVQEPVDQREQLDYHALNAMLNLYNDAGEIQFDKDREAANQYFLQHVNQNTVYFHDLEEKVKYLVDNEYYDP
EVLDQYEFSFVKSLFKQAYAKKFRFQSFLGAYKYYTSYTLKTFDGRRYLERFEDRVCMVALGLAAGDTELASNLVDEIMD
GRFQPATPTFLNIGKKQRGEPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLSNVREAGAPIKHIENQSSGVIPV
MKLLEDAFSYANQLGARQGAGAVYLSAHHPDILRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKRNDDMYLFSPYDV
ERVYGKPFADVSITEHYEEMVEDPRIRKSKINARAFFQTLAEIQFESGYPYIMFEDTVNKANPIEGRITHSNLCSEILQV
STPSEFNADLSYKQIGDDISCNLGSMNIAKAMDSEDFSKTIETAIRGLTAVADQTSIDSVPSVRQGNDNSHAIGLGQMNL
HGFLGREHIHYGSEEALDFTNAYFATVMYEALKASNKIAQERGEKFHNFENSQYATGEFFDRYDPAEFAPKTERIRQIIG
NSSIQVPTAQDWQQLKDDVQAHGLYNRNLQAIPPTGSISYINNSTSSIHPIASKIEIRKEGKIGRVYYPAPYMTNDNLEY
YEDAYEIGYEKIIDTYAVATKYVDQGLSLTLFFKDTATTRDINRAQIYAWRKGIKTIYYIRLRQTALTGTEVEGCVSCML

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 0.0 86