Gene Information

Name : smpB (jk0458)
Accession : YP_250233.1
Strain : Corynebacterium jeikeium K411
Genome accession: NC_007164
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 554828 - 555382 bp
Length : 555 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGCAGCAAAAAAGAGCACTCCCACCGATTCGGGGAAATCGAAGGGGAAGAAGAACAAGGCCCAGAAGGGCGCAGGTCA
GAAGGGGGCTGGCCAGATCGTCGTTGCCACCAACCGTAAGGCGCGCCACGATTACCACATCATCGATACCTACGAGTGCG
GTGTGGTTCTGGTGGGCACGGAAGTTAAGTCTTTGCGTGAGGGCAAGGCTTCTCTTGTTGACGCCTACGCCACCATCGAC
GAAGGTGAAGTCTGGCTGCGCGGCCTTCACATCCCGGAGTACTCCATGGGGCACTGGACGAACCACAGTCCCCGCCGTAC
CCGCAAGCTGCTGCTGCACCGCCGGGAGATCGACTCGCTTATGGGCAAGGTTCGCGACGGAAACAACACTTTGGTTCCCT
TGCAGCTGTACTTCGTTGCCGGCAAGTTGAAGGTCGAGCTGGCGCTGGCGCGTGGTAAGCAGGAATACGACAAGCGCCAG
GACATCAAGCGCCGTACGGAAGAGCGAGAGATCACGCGCGAGATGGGCCGGCGGATTAAGGGGATCCAGGGCTAG

Protein sequence :
MAAKKSTPTDSGKSKGKKNKAQKGAGQKGAGQIVVATNRKARHDYHIIDTYECGVVLVGTEVKSLREGKASLVDAYATID
EGEVWLRGLHIPEYSMGHWTNHSPRRTRKLLLHRREIDSLMGKVRDGNNTLVPLQLYFVAGKLKVELALARGKQEYDKRQ
DIKRRTEEREITREMGRRIKGIQG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 8e-52 88
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 2e-28 54
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 2e-20 43