Gene Information

Name : thyA (jk0441)
Accession : YP_250216.1
Strain : Corynebacterium jeikeium K411
Genome accession: NC_007164
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 528170 - 528991 bp
Length : 822 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
GTGGCACCCCAGCAGCAGCCGAGTTCCATCCCCACCCCATACGAGGATCTTCTGCGGGAGATCCTCGAGACCGGCACCCC
CAAGGGCGATCGCACCGGCACGGGTACCACCAGCCTGTTTGGCCGCCAGATCCGCTACGACCTCTCCGCAGGTTTCCCGC
TGATCACTACCAAGTCGGTACATGTGAAGTCCGTGGTGGGTGAACTGCTGTGGTTCCTCCGCGGAGATTCCAACGTGCGC
TGGCTACAGGAGAACGGTATTCGCATCTGGAACGAGTGGGCTGACGAGAACGGTGATCTAGGCCCGGTATACGGCGTGCA
GTGGCGCAGCTGGCCGACTCCAAACGGCCAGCACATCGACCAGATCGCCGGCGCGTTGGAAACTCTGCAAACTAACCCGG
ATTCGCGTCGCAATATCGTCAGCGCCTGGAACGTCTCGGAGCTGGACAACATGGCCCTTCCACCATGCCACCTGCTGTTC
CAGCTGTACGTGGCCAACGGCAAGCTGAGTTGCCAGCTGTACCAGCGCAGCGCGGACATGTTCCTGGGCGTGCCGTTCAA
CATCGCCAGCTACTCGCTGCTGACCCACATGTTCGCCCAGCAGGCGGGCCTGGAGGTCGGCGAGTTCATCTGGACCGGCG
GTGATTGCCACATCTACGACAATCACGTGGAGCAGGTTAAGCTGCAGCTTTCCCGCGATGCCCGCCCGTATCCGCAGCTG
AAGCTGAACAAGGCTGCGGACATGTTTTCTTACGACTTTTCCGATATCGAGTTCACCGGCTACGACCCGCATCCGGTGAT
TAAGGCAAAGGTGGCCGTGTAA

Protein sequence :
MAPQQQPSSIPTPYEDLLREILETGTPKGDRTGTGTTSLFGRQIRYDLSAGFPLITTKSVHVKSVVGELLWFLRGDSNVR
WLQENGIRIWNEWADENGDLGPVYGVQWRSWPTPNGQHIDQIAGALETLQTNPDSRRNIVSAWNVSELDNMALPPCHLLF
QLYVANGKLSCQLYQRSADMFLGVPFNIASYSLLTHMFAQQAGLEVGEFIWTGGDCHIYDNHVEQVKLQLSRDARPYPQL
KLNKAADMFSYDFSDIEFTGYDPHPVIKAKVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 2e-113 84