Gene Information

Name : leuS (jk2075)
Accession : YP_251875.1
Strain : Corynebacterium jeikeium K411
Genome accession: NC_007164
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 2427237 - 2430167 bp
Length : 2931 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGACCAACGGCAGCACTGAAGACAATTCTTACCGCTACACTCCAGGCCTTGCGGCCAAGATCGAGGCCAAGTGGCAGAA
GCACTGGGCCGACAAAGGCACGTTTAACGCCCCGAACCCGACGGGCGACCTGGCGGAGCCGGGCGCGGAGCTGCCGGAGG
ACCGCAAGTTTATCCAGGACATGTTCCCTTACCCCTCCGGCGTGGGTCTGCACGTGGGCCACCCGCTGGGTTACATCGGT
ACGGACGTGTTTGCGCGCTTCCACCGCATGAAGGGCGCAAATGTGCTGCATACGCTGGGTTACGATGCCTTCGGCCTGCC
CGCCGAGCAGTACGCTGTGCAGACCGGCACCCACCCGCGCACCACCACTATGGCCAACATTGCCAACATGGAGCGCCAGC
TGGGCCGCCTGGGCCTGGGCCACGACAAGCGCCGCAGCTTCGCCACCACGGATACGGATTACTACCGCTGGACGCAGTGG
ATCTTCCTGCAGATTTACAACTCCTGGTTTGACCCGGAGGCCAAAAACGCCAATGGCACCCTGGGCAAGGCTCGCCCGAT
TAAGGAGCTGGAGGAAAAGCTCGCTGCCGAGCGCGCCGACTGGGCGGATCTCAGCGCCGCCGAGAAGCAGGAGATCCTGG
ATAGCTACCGCCTGGTCTACCGCTCGAACTCGACGGTGAACTGGTGCCCTGGCCTCGGCACTGTGCTGGCGAATGAGGAG
GTCACGGCGGAGGGGCGCTCGGAGCGCGGCAACTTCCCCGTCTTCCGCAAGAACCTGCAGCAGTGGATGATGCGCATCAC
CGCGTACTCCGACCGGCTTATCGACGACCTGGAGTACCTGGACTGGCCGGAGAAGGTGAAGTCCATGCAGCGCAACTGGA
TCGGCCGGTCGCGCGGCGCGGAGGTCACGTTCGACTGCCTGGGCAACGACATTGACGTGTTCACCACGCGCCCGGACACG
CTGTTCGGCGCGACGTACATGGTGCTGGCCCCGGAGCACGAGCTGGTGGATACGCTCGTTGCGCAGTCCGGTAATTCTTC
TTCGGGTAGTGACGCCTACACGGATGTCGACCCACGGTGGACCTACGGCCAGGCAAACCCGGCCGCCGCGGTGGAGGCAT
ACCGCGCGGCAATCGCCGCCAAGTCGGACTTGGAGCGCCAGGAGAACAAGGAGAAGACGGGCGTTTTCCTGGGCGTTTAT
GCTACTAACCCGGTGAACGGCGCACAGGTGCCGGTCTTCATCGCTGACTACGTGCTGACGGGCTACGGCACCGGCGCGAT
CATGGCTGTGCCCGCGCACGATTCCCGCGACTTTGAGTTCGCCACCGAGTTCGGGCTGCCGATTGTGCCGGTGCTGGCGC
CGGAGGGCGCCGAGGCTGGCGCAGGCGAGCAGGGTGGCGCCGAGCTCACCGAGGCTTTCACCGAGGACGGCCCGCACATC
AACTCCAACAACTCCGACGGCCTGGAGCTCAACGGCCTGGGCAAGGCGGAAGCTATCGACAAAGCCATCGAGTGGTTGGA
ATCCAAGGGTGTAGGCAGCGGCAAGATCCAGTACAAGCTGCGTGACTGGCTGTTCGCCCGCCAGCGCTACTGGGGCGAGC
CCTTCCCCATCGTCTATGACGAAGACGGTACGGCACACGGCCTGCCGGAAGACATGCTCCCCGTCGAGCTGCCCGAAGTG
GAGGATTACAAGCCCGTCAGCTTCGACCCGGACGATAAGGATTCCGCCCCCCAGCCCCCGCTGGCCAAGGCCAAGGACTG
GGTCGAAGTCACCCTGGACCTCGGCGACGGAGAAAAGACCTACTACCGCGACACGAACGTCATGCCGCAGTGGGCAGGTT
CCTCCTGGTACCAGCTGCGCTATATCGACCCGAACAATGACAATGCCCTGGTAGACATTGAAAACGAGCGCTACTGGGTC
GGCCCGCGCGAAGGCCGCCCCTCCGGCGGCGTGGACCTGTACGTCGGCGGCGTGGAGCATGCAGTGCTGCACCTGCTATA
CGCCCGCTTCTGGCACAAGGTGCTGTTCGACCTCGGCGTAGTCTCTAGCTTCGAGCCCTACTACCGCCTCTACAACCAGG
GCTACATCCAGGCCTACGCCTACACGGATTCCCGCGGCGTGTACGTTCCCGCGGAGGAGGTCACCGAACGCGACGGTAAG
TTCTTCTGGGTTCGCAAGGCGGATGATGCTGAGGGCGTCACAAAGGAAGAAGAAGTATTCCAGGAATACGGCAAGATGGG
TAAGTCCCTCAAGAACGCGGTCTCGCCCGACGAGATCTGCGACGACTACGGTGCGGATACCCTGCGCGTTTACGAGATGG
CGATGGGTCCGCTCGACACGTCGCGGCCGTGGGCTACGAAGGACGTGGTCGGCGCGCAGCGATTCCTGCAGCGCGCGTGG
CGCCTCGCCGTCGACGAGAACACGGGTAAGGGTTCTGTGAGCGATGACGCCCTCACGGATGAAGACCTAAAAGCCCTGCA
CAGGACCATCGCGGGGGTTCACGAAAACTATGCAGAGCTGCGCGACAACACGGCTGTAGCGAAGCTGATTGAGTACGTGA
ACTACCTGACGAAAACCTACTCCGCCGGGCAGGCTCCGCGGGCAGCCGTGGAACCGCTGGTGCAGATGCTGTCGCCGGTG
GCGCCGCACATCGCCGAGGAGATGTGGGAGATCCTGGGCCACTCCGAGGGTATTACTTATGAGTCCTTCCCCGAGTGGGA
TGAAAAGTGGCTGGTGGATGACACTATTGAGTTGCCAGTGCAGGTGATGGGCAAGCTGCGCGGTCGCATTAACGTGGCGG
CGGATGCTTCGCGGGAGGACATTGAGGCTGCTGCGCTGGAGGAGCCGAATGTCGCTTCGCACATTGAGGGCAAGACGGTG
GCGAAGATCATCGTGGTGCCGGGCAAGATGGTGAATATCGTCGCGAAGTAG

Protein sequence :
MTNGSTEDNSYRYTPGLAAKIEAKWQKHWADKGTFNAPNPTGDLAEPGAELPEDRKFIQDMFPYPSGVGLHVGHPLGYIG
TDVFARFHRMKGANVLHTLGYDAFGLPAEQYAVQTGTHPRTTTMANIANMERQLGRLGLGHDKRRSFATTDTDYYRWTQW
IFLQIYNSWFDPEAKNANGTLGKARPIKELEEKLAAERADWADLSAAEKQEILDSYRLVYRSNSTVNWCPGLGTVLANEE
VTAEGRSERGNFPVFRKNLQQWMMRITAYSDRLIDDLEYLDWPEKVKSMQRNWIGRSRGAEVTFDCLGNDIDVFTTRPDT
LFGATYMVLAPEHELVDTLVAQSGNSSSGSDAYTDVDPRWTYGQANPAAAVEAYRAAIAAKSDLERQENKEKTGVFLGVY
ATNPVNGAQVPVFIADYVLTGYGTGAIMAVPAHDSRDFEFATEFGLPIVPVLAPEGAEAGAGEQGGAELTEAFTEDGPHI
NSNNSDGLELNGLGKAEAIDKAIEWLESKGVGSGKIQYKLRDWLFARQRYWGEPFPIVYDEDGTAHGLPEDMLPVELPEV
EDYKPVSFDPDDKDSAPQPPLAKAKDWVEVTLDLGDGEKTYYRDTNVMPQWAGSSWYQLRYIDPNNDNALVDIENERYWV
GPREGRPSGGVDLYVGGVEHAVLHLLYARFWHKVLFDLGVVSSFEPYYRLYNQGYIQAYAYTDSRGVYVPAEEVTERDGK
FFWVRKADDAEGVTKEEEVFQEYGKMGKSLKNAVSPDEICDDYGADTLRVYEMAMGPLDTSRPWATKDVVGAQRFLQRAW
RLAVDENTGKGSVSDDALTDEDLKALHRTIAGVHENYAELRDNTAVAKLIEYVNYLTKTYSAGQAPRAAVEPLVQMLSPV
APHIAEEMWEILGHSEGITYESFPEWDEKWLVDDTIELPVQVMGKLRGRINVAADASREDIEAAALEEPNVASHIEGKTV
AKIIVVPGKMVNIVAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 4e-152 47