Gene Information

Name : guaA (jk1720)
Accession : YP_251515.1
Strain : Corynebacterium jeikeium K411
Genome accession: NC_007164
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2007506 - 2009095 bp
Length : 1590 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGACTCAACAAGACCCAGCTGCCGCCGCTCCACGGCCCGTACTTGTCGTGGATTTCGGCGCGCAATACGCACAGCTCAT
TGCCCGCCGGGTGCGCGAGGTGAACCTGTACTCCGAGGTCATCCCGCACACCATGCCCGCCGACGAGGTCGCCGCGAAGA
ACCCCGCGGCCCTGATCCTTTCCGGTGGCCCTTCTTCTGTTTATGCAGATGACGCCCCCTCGCTTCACCCCGAACTGTTG
GAGCTAGGGGTGCCGGTATTCGGCATCTGCTACGGCTTCCAAGCAATGACCCAGGCCATGGGTGGAACCGTGGCGAAGAC
CGGCCTGCGCGAGTACGGCCGTACCGAGCTGCAGATCCAGTCGGAGGCTGGCGTGCTGCACGAGGGCATGGGGGAGAGCC
AGCAGGTGTGGATGAGCCACGGCGACTCCGTCTCTGAGGCGCCGGAGGGCTTCACCGTGACCGCCCGCACCGAGGGTGCG
CCGGTGGCCGCCTTTGAGTGCCCGGAGAAGCGCATGGCGGGCGTGCAGTACCACCCCGAGGTTCTGCACTCCCCGAAGGG
CCAGGAGGTGCTGCGCCGCTTCCTGCTGGAAACCGCCGGGTTGGAGCCGACCTGGACCGCGGGCAACATTGCCGAGCAGC
TGATTGAGCAGGTGCGCGAGCAGATCGGCGACGAAGGGCGCGCTATCTGCGGCCTGTCCGGTGGCGTGGATTCCGCCGTG
GCCGCCGCGCTGGTGCAACGTGCGATTGGTGACCGACTGACCTGTGTGTTCGTCGATCATGGCCTGCTGCGCGCCGGCGA
GCGCGAGCAGGTGGAGAAGGACTTCGTTGCCGCCACTGGTGCGAAGCTGGTGACGGTGGACGAGCGCGAGGCGTTCCTGC
AGAAGCTGGCCGGCGTGACTGAGCCGGAGGCTAAGCGCAAGGCCATCGGCGCGGAGTTCATCCGCTCCTTCGAGCGCGCC
GTTGCGGGCGTGCTGGCTGATGCCCCGGAGGGATCCAGCGTGGACTTCCTGGTGCAGGGCACGCTGTACCCGGATGTCGT
GGAATCCGGTGGCGGCACCGGCACCGCGAACATTAAGAGCCACCACAACGTCGGCGGCCTGCCGGACGATGTGGAGTTCG
AACTGGTGGAGCCGCTGCGCCTGTTGTTCAAGGACGAGGTTCGCGCGGTTGGTCGCGAGCTGGGCCTGCCGGAGGAAATC
GTGGCACGCCAGCCATTCCCGGGGCCGGGTCTGGGCATCCGCATCATCGGTGAAGTGACGGAGGATCGCCTGGAGACTCT
GCGTGCTGCTGACGCTATTGCCCGCGCCGAGCTCACCGCCGCGGGCTTGGACGATGTGATCTGGCAGTGCCCGGTGGTTC
TGCTGGCGGACGTGCGCTCCGTGGGTGTGCAGGGCGATGGCCGTACCTACGGCCACCCGATCGTGCTGCGCCCGGTATCC
AGTGAGGACGCGATGACGGCCGACTGGACCCGCATTCCTTTCGACGTGTTGGAGAAGATCTCCACGCGCATCACCAACGA
GGTGGAGGAAGTGAACCGCGTGGTGCTGGACGTCACCAGCAAGCCGCCGGGAACCATCGAGTGGGAATAA

Protein sequence :
MTQQDPAAAAPRPVLVVDFGAQYAQLIARRVREVNLYSEVIPHTMPADEVAAKNPAALILSGGPSSVYADDAPSLHPELL
ELGVPVFGICYGFQAMTQAMGGTVAKTGLREYGRTELQIQSEAGVLHEGMGESQQVWMSHGDSVSEAPEGFTVTARTEGA
PVAAFECPEKRMAGVQYHPEVLHSPKGQEVLRRFLLETAGLEPTWTAGNIAEQLIEQVREQIGDEGRAICGLSGGVDSAV
AAALVQRAIGDRLTCVFVDHGLLRAGEREQVEKDFVAATGAKLVTVDEREAFLQKLAGVTEPEAKRKAIGAEFIRSFERA
VAGVLADAPEGSSVDFLVQGTLYPDVVESGGGTGTANIKSHHNVGGLPDDVEFELVEPLRLLFKDEVRAVGRELGLPEEI
VARQPFPGPGLGIRIIGEVTEDRLETLRAADAIARAELTAAGLDDVIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVS
SEDAMTADWTRIPFDVLEKISTRITNEVEEVNRVVLDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 0.0 86
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-128 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-128 51
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-128 51