Gene Information

Name : merA (jk1442)
Accession : YP_251233.1
Strain : Corynebacterium jeikeium K411
Genome accession: NC_007164
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.16.1.1
Position : 1699014 - 1700435 bp
Length : 1422 bp
Strand : +
Note : -

DNA sequence :
ATGCCTACGAAGTACGATCTCGCCATCATCGGATCGGGAGGCGGCGCGTTCGCCGCTGCGATCCGCGCCAGCACGCTCGG
GAAGTCGGTGGTGATGATCGAGCGCGGGACGCTCGGCGGCACCTGCGTGAACACGGGCTGCGTCCCGTCGAAGGCGCTCA
TTGCCGCGGCCGGCGCGCGGCACGTCGCGGTCGACGCCGCAACCCGGTTCCCCGGGATCGCGACGACGGCGGATCCCGTC
GACATGCCCGCGCTGATCGCTGGGAAGCAAGCGTTGGTGGAGTCGCTGCGCGGCGAGAAGTACGCCGACGTCGCCGACTC
CTACGGCTGGCAGGTCCTCCGCGGCGACGCCTCGTTCGTGGGCACCCCTGATGCGCCGGTTCTCGATGTTGCCGGATCCG
ACGGAAGCGTCGAGACCATCGAGGCCCACCACTACCTGGTCGCGACTGGTTCTCGCCCGTGGGCACCGCCGATCGACGGC
CTGGAGGAGACCGGATACCTGACCTCGACCACGGCGATGGAGCTGACGGAGGTCCCCGAGTCGCTGCTGGTGCTCGGCGG
CGGCTACGTCGCCCTGGAGCAGGCGCAGCTGTTCGCCCGCCTCGGCTCGCAGGTCACGCTGCTCGTGCGGTCCCGGCTCG
CCTCGAAGGAGGAGCCGGAGGTGTCGAAGGCGCTCCAGGAGGTGTTCGCCGACGAGGGCATCCGCGTCGTCAGCCGCGCA
GTGCCCACCCGGGTCTCCCGCGGCACGGGAGGCGAGGCCGTCGTGACCGCCGCCTTGTCCGGCGGCTCGCAGGAGTTCCG
CGCCGACCAGGTCCTGGTCGCCCTCGGACGCCGTCCCGTCACCGATGGCCTGAACCTCGATGCGGTCGGGGTGAATACCG
GAGACTCCGGCGAGGTGGTCGTCTCCGACCGGCTGCAGTCCTCGAACCCGCGGGTCTGGGCCGCGGGCGACGTGACCGGG
CACCCCGAGTTCGTCTACGTCGCCGCCCACCACGGCACCCTCGTCGCCGAGAACGCGTTCGCCGACGCCGACCGGTCCGT
CGACTACGCCCGCCTGCCGCGGGTGACGTTCACCGGGACCGCGATCGGCGCGGTCGGGATGACCGAGAAGGACGTCCTCG
CCGCGGGGATCCGCTGCGACTGCCGCGTCCTGCCCCTGCACCACGTGCCCCGCGCCTTGGTGAACCGCGACACCCGCGGG
TTCATCAAGATCGTCGTGAACGCCGAGACGAAAGAGATCCTCGGCCTGACCGCCGTCGCCAAGGACGCCGGGGAGCTCGC
CGCCGCAGGCGTCCACGTGCTCGGCAGGACCGTCGCCGAGGTCGCCAACGCCTGGGCCCCCTACCTGACCATGGCCGAGG
GCATCCGGATCGCCGCGAAGGCCTTCACCACCGACCCGTCGCTGCTGTCGTGCTGCGCATGA

Protein sequence :
MPTKYDLAIIGSGGGAFAAAIRASTLGKSVVMIERGTLGGTCVNTGCVPSKALIAAAGARHVAVDAATRFPGIATTADPV
DMPALIAGKQALVESLRGEKYADVADSYGWQVLRGDASFVGTPDAPVLDVAGSDGSVETIEAHHYLVATGSRPWAPPIDG
LEETGYLTSTTAMELTEVPESLLVLGGGYVALEQAQLFARLGSQVTLLVRSRLASKEEPEVSKALQEVFADEGIRVVSRA
VPTRVSRGTGGEAVVTAALSGGSQEFRADQVLVALGRRPVTDGLNLDAVGVNTGDSGEVVVSDRLQSSNPRVWAAGDVTG
HPEFVYVAAHHGTLVAENAFADADRSVDYARLPRVTFTGTAIGAVGMTEKDVLAAGIRCDCRVLPLHHVPRALVNRDTRG
FIKIVVNAETKEILGLTAVAKDAGELAAAGVHVLGRTVAEVANAWAPYLTMAEGIRIAAKAFTTDPSLLSCCA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 2e-85 44
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 2e-85 44
merA ABQ57371.1 MerA Not tested SGI1 Protein 5e-68 44
merA AGK07021.1 MerA Not tested SGI1 Protein 5e-68 44
merA AGK07079.1 MerA Not tested SGI1 Protein 5e-68 44
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 7e-69 44
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 2e-66 43
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 4e-65 43
merA AFG30120.1 MerA Not tested PAGI-2 Protein 4e-65 43
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 5e-65 43
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 4e-66 43
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 2e-65 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merA YP_251233.1 mercuric reductase BAC0651 Protein 1e-85 44
merA YP_251233.1 mercuric reductase BAC0652 Protein 1e-67 44
merA YP_251233.1 mercuric reductase BAC0224 Protein 3e-83 44
merA YP_251233.1 mercuric reductase BAC0653 Protein 6e-65 41